Alpha and beta proteins (a+b) Class

Fold Superfamilies Families
Microbial ribonucleases 1 3
Lysozyme-like 1 11
Cysteine proteinases 1 22
His-Me finger endonucleases 1 6
RNase A-like 1 1
Prion-like 1 1
LysM domain 1 1
Urease, gamma-subunit 1 1
IL8-like 2 2
DNA-binding domain 1 4
Penicillin-binding protein 2x (pbp-2x), c-terminal domain 1 1
Ribosomal proteins S24e, L23 and L15e 1 3
HIT-like 2 5
Ribosomal protein S5 domain 2-like 1 12
beta-Grasp (ubiquitin-like) 14 27
FAD-linked reductases, C-terminal domain 1 7
Cystatin-like 7 45
ssDNA-binding transcriptional regulator domain 1 4
MHC antigen-recognition domain 1 1
UBC-like 1 4
Diaminopimelate epimerase-like 1 4
GFP-like 1 2
Tubby C-terminal domain-like 1 2
Pili subunits 1 7
Mitochondrial glycoprotein MAM33-like 1 1
FKBP-like 3 5
Ribosomal protein S16 1 1
Ribosomal protein S19 1 1
Ribosomal protein L31e 1 1
Allophycocyanin linker chain (domain) 1 1
Cdc48 domain 2-like 1 1
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 1 10
SecB-like 1 2
DNA-binding domain of Mlu1-box binding protein MBP1 1 1
Heme-binding protein A (HasA) 1 1
Chalcone isomerase 1 1
CBS-domain pair 1 1
Thioesterase/thiol ester dehydrase-isomerase 1 8
DLC 1 1
CI-2 family of serine protease inhibitors 1 1
alpha/beta-Hammerhead 5 7
POZ domain 1 2
EF-Ts domain-like 2 2
Fe,Mn superoxide dismutase (SOD), C-terminal domain 1 1
ClpS-like 1 2
Ribosomal L11/L12e N-terminal domain 1 1
Anti-LPS factor/recA domain 2 2
Signal recognition particle alu RNA binding heterodimer, SRP9/14 1 1
dsRBD-like 5 9
Eukaryotic type KH-domain (KH-domain type I) 1 1
Alpha-lytic protease prodomain-like 10 11
Ribosomal protein S3 C-terminal domain 1 1
Enolase N-terminal domain-like 1 1
Ribosomal protein L22 1 1
GroEL-intermediate domain like 1 2
DNA damage-inducible protein DinI 1 1
Ferredoxin-like 59 127
Ribosomal protein L30p/L7e 1 1
Probable bacterial effector-binding domain 1 4
LigT-like 1 4
Pepsin inhibitor-3 1 1
CYTH-like phosphatases 1 2
eIF1-like 2 2
Hedgehog/DD-peptidase 1 5
Alpha-L RNA-binding motif 1 5
RRF/tRNA synthetase additional domain-like 4 5
IF3-like 8 10
Yeast killer toxins 1 2
Cell division protein MinE topological specificity domain 1 1
Cyanase C-terminal domain 1 1
RuBisCO, small subunit 1 1
DCoH-like 5 7
MutS N-terminal domain-like 2 2
GYF/BRK domain-like 2 2
RL5-like 1 2
RPB5-like RNA polymerase subunit 1 1
Bacillus chorismate mutase-like 9 12
Tautomerase/MIF 1 6
FwdE/GAPDH domain-like 4 9
N domain of copper amine oxidase-like 5 6
Aha1/BPI domain-like 2 2
Subtilisin inhibitor 1 1
RNA bacteriophage capsid protein 1 1
eIF4e-like 1 2
CO dehydrogenase flavoprotein C-domain-like 2 2
SRF-like 1 1
Origin of replication-binding domain, RBD-like 1 5
FMN-dependent nitroreductase-like 1 2
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 1 1
Zincin-like 2 20
SH2-like 1 1
HPr-like 2 2
Homing endonuclease-like 2 3
T-fold 2 6
Cell cycle regulatory proteins 1 1
BLIP-like 2 2
Ribosomal protein L9 C-domain 1 1
MbtH/L9 domain-like 2 3
Ribonuclease PH domain 2-like 1 1
Regulatory factor Nef 1 1
CytB endotoxin-like 1 1
Class II aaRS and biotin synthetases 1 4
Subdomain of clathrin and coatomer appendage domain 1 2
SCP-like 1 4
Mog1p/PsbP-like 1 4
Acyl-CoA N-acyltransferases (Nat) 1 10
Gelsolin-like 3 4
Profilin-like 10 24
PR-1-like 1 1
Phoshotransferase/anion transport protein 1 2
Nudix 1 7
5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain 1 1
YrdC/RibB 1 2
YbaK/ProRS associated domain 1 1
Thymidylate synthase/dCMP hydroxymethylase 1 1
N-acetylmuramoyl-L-alanine amidase-like 1 1
Cytochrome b5-like heme/steroid binding domain 1 2
DNA topoisomerase I domain 1 1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 1 4
Sporulation response regulatory protein Spo0B 1 1
Ribonuclease Rh-like 1 1
Ornithine decarboxylase C-terminal domain 1 1
Pentein, beta/alpha-propeller 1 7
Creatinase/aminopeptidase 1 1
Glutamine synthetase/guanido kinase 1 5
TBP-like 11 22
S-adenosylmethionine synthetase 1 1
DNA clamp 1 2
Molybdenum cofactor-binding domain 1 1
Nitrite and sulphite reductase 4Fe-4S domain-like 1 1
The spindle assembly checkpoint protein mad2 1 1
Phospholipase D/nuclease 1 5
Monooxygenase (hydroxylase) regulatory protein 1 1
PurM C-terminal domain-like 1 1
Ribosomal protein S8 1 1
Ribosomal protein L6 1 1
ATP-grasp 2 13
SAICAR synthase-like 1 3
Protein kinase-like (PK-like) 1 7
FAD-binding/transporter-associated domain-like 1 4
Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 1 1
Methenyltetrahydromethanopterin cyclohydrolase 1 1
Hect, E3 ligase catalytic domain 1 1
Nitrile hydratase alpha chain 1 1
4'-phosphopantetheinyl transferase 1 2
DNase I-like 1 3
Aldehyde ferredoxin oxidoreductase, N-terminal domain 1 1
Ntn hydrolase-like 2 8
DmpA/ArgJ-like 1 2
Pyruvoyl-dependent histidine and arginine decarboxylases 1 2
S-adenosylmethionine decarboxylase 1 2
Metallo-hydrolase/oxidoreductase 1 14
Metallo-dependent phosphatases 1 12
Carbon-nitrogen hydrolase 1 2
ADC synthase 1 1
LDH C-terminal domain-like 1 2
DNA breaking-rejoining enzymes 1 2
SMAD MH1 domain 1 1
Ribosome inactivating proteins (RIP) 1 2
ADP-ribosylation 1 7
Peptide deformylase 1 1
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 1 1
C-type lectin-like 1 8
SRCR-like 2 3
Fibrinogen C-terminal domain-like 1 1
gp120 core 1 1
Methionine synthase activation domain-like 1 2
Nitric oxide (NO) synthase oxygenase domain 1 1
Penicillin binding protein dimerisation domain 1 1
Oxidoreductase molybdopterin-binding domain 1 1
FAH 1 1
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains 1 1
Substrate-binding domain of HMG-CoA reductase 1 1
Conserved core of transcriptional regulatory protein vp16 1 1
Insert subdomain of RNA polymerase alpha subunit 1 1
Baseplate structural protein gp11 1 1
Major capsid protein gp5 1 1
Non-globular alpha+beta subunits of globular proteins 1 3
Prim-pol domain 1 3
LuxS/MPP-like metallohydrolase 1 2
SAND domain-like 1 2
gpW/XkdW-like 2 2
Photosystem I subunit PsaD 1 1
Prokaryotic ribosomal protein L17 1 1
PX domain 1 1
Chorismate lyase-like 1 3
YlxR-like 1 1
Hsp33 domain 1 1
CNF1/YfiH-like putative cysteine hydrolases 1 3
YopH tyrosine phosphatase N-terminal domain 1 1
Outer capsid protein sigma 3 1 1
DNA-binding domain of intron-encoded endonucleases 1 1
Protein-L-isoaspartyl O-methyltransferase, C-terminal domain 1 1
Secretion chaperone-like 5 7
MotA C-terminal domain-like 1 1
Integrin beta tail domain 1 1
SRP19 1 1
Transcription factor NusA, N-terminal domain 1 1
DsrC, the gamma subunit of dissimilatory sulfite reductase 1 1
Ribosome binding protein Y (YfiA homologue) 1 1
GTP cyclohydrolase I feedback regulatory protein, GFRP 1 1
YggU-like 1 1
Thymidylate synthase-complementing protein Thy1 1 1
MTH1598-like 1 1
LCCL domain 1 1
Argininosuccinate synthetase, C-terminal domain 1 1
beta-hairpin-alpha-hairpin repeat 2 2
TolA/TonB C-terminal domain 1 2
VSV matrix protein 1 1
Hypothetical protein MTH1880 1 1
Smc hinge domain 1 1
Rotavirus NSP2 fragment, N-terminal domain 1 1
Nucleotidyltransferase 1 14
PP2C-like 1 1
Metal cation-transporting ATPase, ATP-binding domain N 1 1
Nuclease A inhibitor (NuiA) 1 1
YbaB-like 1 1
Polo-box domain 1 2
SufE/NifU 1 3
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 1 1
GIY-YIG endonuclease 1 1
OsmC-like 1 2
Replication modulator SeqA, C-terminal DNA-binding domain 1 1
MesJ substrate recognition domain-like 1 1
Dodecin subunit-like 6 6
Receptor-binding domain of short tail fibre protein gp12 1 1
Mago nashi protein 1 1
Inhibitor of vertebrate lysozyme, Ivy 1 1
Proguanylin 1 1
FYSH domain 1 2
DNA-binding protein Tfx 1 1
Hypothetical protein YjiA, C-terminal domain 1 1
Hypothetical protein TM0875 1 1
GCM domain 1 1
Pseudouridine synthase 1 4
Lesion bypass DNA polymerase (Y-family), little finger domain 1 1
Hypothetical protein Yml108w 1 1
Ribosome binding domain-like 2 2
Obg GTP-binding protein C-terminal domain 1 1
Colicin D/E5 nuclease domain 1 2
Cell division protein ZapA-like 1 1
NSFL1 (p97 ATPase) cofactor p47, SEP domain 1 1
mRNA decapping enzyme DcpS N-terminal domain 1 1
Chromosomal protein MC1 1 1
Coproporphyrinogen III oxidase 1 1
Hypothetical protein Ta1206 1 1
Folate-binding domain 1 2
Hypothetical protein YwqG 1 1
CheC-like 1 1
Hypothetical protein YoaG 1 1
Nucleocapsid protein dimerization domain 1 2
Tombusvirus P19 core protein, VP19 1 1
Ta1353-like 1 1
Hypothetical protein TM0160 1 1
Chorismate synthase, AroC 1 1
Hypothetical protein HI1480 1 1
Suppressor of Fused, N-terminal domain 1 1
Hypothetical protein PH1602 1 1
NinB 1 1
PurS-like 1 2
Hypothetical protein MTH677 1 1
Hypothetical protein SAV1430 1 1
ParB/Sulfiredoxin 1 4
Gamma-glutamyl cyclotransferase-like 1 1
2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 1 1
HSP90 C-terminal domain 1 1
Dystroglycan, domain 2 1 1
YjbQ-like 1 1
Hypothetical protein PF0899 1 1
Hut operon positive regulatory protein HutP 1 1
Hypothetical protein yfbM 1 1
Bacillus phage protein 1 1
Ligand-binding domain in the NO signalling and Golgi transport 1 3
YggX-like 1 1
Sulfolobus fructose-1,6-bisphosphatase-like 1 1
Hemolytic lectin CEL-III, C-terminal domain 1 1
SSo0622-like 1 1
Putative modulator of DNA gyrase, PmbA/TldD 1 1
TrkA C-terminal domain-like 1 1
DNA methylase specificity domain 1 2
GTF2I-like repeat 1 1
WWE domain 1 1
AF0104/ALDC/Ptd012-like 1 3
YehU-like 1 1
DNA mismatch repair protein MutL 1 1
Phosphoprotein M1, C-terminal domain 1 1
EndoU-like 1 2
TFB5-like 1 1
YktB/PF0168-like 1 2
WGR domain-like 1 1
RelE-like 1 2
Ns1 effector domain-like 1 1
Kinetochore globular domain-like 1 2
L35p-like 1 1
Coronavirus NSP8-like 1 1
BB1717-like 1 1
TTHA1013/TTHA0281-like 1 2
NAP-like 1 1
YefM-like 1 1
Nqo5-like 1 1
THUMP domain 1 3
AMMECR1-like 1 1
VC0467-like 1 1
ImmE5-like 1 1
TM1622-like 1 1
Antiparallel beta/alpha barrel (PT-barrel) 1 1
PUG domain-like 1 1
TRCF domain-like 1 1
MK0786-like 1 1
YkuJ-like 1 1
SARS receptor-binding domain-like 1 1
TTHA1528-like 1 1
YojJ-like 1 1
STIV B116-like 1 1
PHP14-like 1 2
Phage tail protein-like 1 2
DUSP-like 1 1
L28p-like 1 2
XisI-like 1 1
DeoB insert domain-like 1 1
CorA soluble domain-like 1 1
PF0523-like 1 1
ERH-like 1 1
NE0471 N-terminal domain-like 1 1
RGC domain-like 1 1
UbiD C-terminal domain-like 1 1
IlvD/EDD N-terminal domain-like 1 1
L,D-transpeptidase pre-catalytic domain-like 1 1
YbiA-like 1 1
AF2331-like 1 1
Oxysterol-binding protein-like 1 1
ORC1-binding domain 1 1
CofE-like 1 1
Peptidoglycan deacetylase N-terminal noncatalytic region 1 1
PH1570-like 1 1
MM3350-like 1 1
GINS/PriA/YqbF domain 1 4
NRDP1 C-terminal domain-like 1 1
SARS Nsp1-like 1 1
Acetoacetate decarboxylase-like 1 1
YegP-like 1 1
CPE0013-like 1 1
YcgL-like 1 1
NMB0488-like 1 1
FlaG-like 1 1
AMPKBI-like 1 1
Shew3726-like 1 1
RplX-like 1 1
SP0830-like 1 1
NosL/MerB-like 1 2
YdfO-like 1 1
BH3703-like 1 1
PG1857-like 1 1
PB2 C-terminal domain-like 1 1
BLRF2-like 1 1
NMB0513-like 1 1
PA1123-like 1 1
Ava3019-like 1 1
SpoVG-like 1 1
EscU C-terminal domain-like 1 1
YonK-like 1 1
SMI1/KNR4-like 1 1
BTG domain-like 1 1
YehR-like 1 1
YqaI-like 1 1
gpW/gp25-like 1 1
TTHC002-like 1 1
NE1680-like 1 1
Lp2179-like 1 1
Rv2827c C-terminal domain-like 1 1
Phosphoprotein oligomerization domain-like 1 1
Taf5 N-terminal domain-like 1 1
Jann2411-like 1 1
ATP12-like 1 1
PSTPO5379-like 1 1
PG1388-like 1 1