Family Assignments

Domains Proteins SCOP Link Families
135 135 SCOP 88854 Protein kinases, catalytic subunit
83 70 SCOP 81269 Extended AAA-ATPase domain
74 73 SCOP 52592 G proteins
70 53 SCOP 81268 Tandem AAA-ATPase domain
57 43 SCOP 52686 ABC transporter ATPase domain-like
47 47 SCOP 51751 Tyrosine-dependent oxidoreductases
36 36 SCOP 47114 Nucleosome core histones
33 33 SCOP 50892 Cyclophilin (peptidylprolyl isomerase)
33 33 SCOP 52375 Class I aminoacyl-tRNA synthetases (RS), catalytic domain
32 32 SCOP 51431 Aldo-keto reductases (NADP)
32 19 SCOP 53068 Actin/HSP70
32 32 SCOP 55682 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
30 30 SCOP 52641 Motor proteins
30 30 SCOP 56251 Proteasome subunits
28 28 SCOP 53417 GABA-aminotransferase-like
27 16 SCOP 63412 MPP-like
26 26 SCOP 53687 Tryptophan synthase beta subunit-like PLP-dependent enzymes
22 22 SCOP 54496 UBC-related
20 20 SCOP 52652 Nitrogenase iron protein-like
20 20 SCOP 56656 Inositol monophosphatase/fructose-1,6-bisphosphatase-like
20 20 SCOP 56802 Acetyl-CoA synthetase-like
19 19 SCOP 53721 ALDH-like
17 17 SCOP 54002 Papain-like
17 17 SCOP 54535 FKBP immunophilin/proline isomerase
16 10 SCOP 54237 Ubiquitin-related
16 13 SCOP 56067 BC ATP-binding domain-like
15 15 SCOP 48265 Cytochrome P450
15 15 SCOP 50979 WD40-repeat
15 15 SCOP 52318 Class I glutamine amidotransferases (GAT)
15 15 SCOP 52541 Nucleotide and nucleoside kinases
15 10 SCOP 53902 Thiolase-related
14 14 SCOP 51800 Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
14 14 SCOP 53384 AAT-like
14 14 SCOP 56310 Protein serine/threonine phosphatase
13 13 SCOP 53255 Cofactor-dependent phosphoglycerate mutase
13 13 SCOP 82568 Ubiquitin carboxyl-terminal hydrolase, UCH
11 11 SCOP 48372 Armadillo repeat
11 11 SCOP 51396 FMN-linked oxidoreductases
11 8 SCOP 52441 BC N-terminal domain-like
11 11 SCOP 53499 Serine carboxypeptidase-like
11 11 SCOP 55348 GAPDH-like
11 11 SCOP 74771 Clathrin adaptor core protein
11 11 SCOP 81605 PP2C-like
10 10 SCOP 51487 beta-glycanases
10 10 SCOP 51570 Class I aldolase
10 10 SCOP 52097 Clp protease, ClpP subunit
10 10 SCOP 52403 N-type ATP pyrophosphatases
10 10 SCOP 52744 Subtilases
10 5 SCOP 56015 Nitrite and sulphite reductase 4Fe-4S domain-like
10 10 SCOP 56205 Hect, E3 ligase catalytic domain
10 10 SCOP 56236 Class II glutamine amidotransferases
10 10 SCOP 101995 PA3696/SPS0176-like
9 9 SCOP 48174 Cryptochrome/photolyase FAD-binding domain
9 9 SCOP 50678 ValRS/IleRS/LeuRS editing domain
9 9 SCOP 51352 Triosephosphate isomerase (TIM)
9 9 SCOP 51622 Pyruvate kinase
9 9 SCOP 52103 Crotonase-like
9 9 SCOP 53402 Cystathionine synthase-like
9 9 SCOP 55505 Neurolysin-like
9 9 SCOP 63381 Ferredoxin reductase FAD-binding domain-like
8 8 SCOP 53272 Phosphoribosyltransferases (PRTases)
8 8 SCOP 53749 Phosphoglycerate kinase
8 8 SCOP 54929 Canonical RBD
8 8 SCOP 55069 Peptide methionine sulfoxide reductase
8 3 SCOP 55974 S-adenosylmethionine synthetase
8 8 SCOP 63984 Sir2 family of transcriptional regulators
8 8 SCOP 81838 BEACH domain
8 8 SCOP 103507 Mitochondrial carrier
8 8 SCOP 110309 Serine acetyltransferase
7 7 SCOP 48426 Sec7 domain
7 7 SCOP 52491 Tubulin, GTPase domain
7 7 SCOP 55074 Adenylyl and guanylyl cyclase catalytic domain
7 7 SCOP 55879 DNA gyrase/MutL, N-terminal domain
7 7 SCOP 55921 Creatinase/aminopeptidase
7 7 SCOP 69557 Spermidine synthase
7 7 SCOP 75305 Amidase signature (AS) enzymes
7 7 SCOP 81656 Meta-cation ATPase, catalytic domain P
7 4 SCOP 82424 Choline/Carnitine O-acyltransferase
7 7 SCOP 111353 Ammonium transporter
6 6 SCOP 48558 L-aspartase/fumarase
6 6 SCOP 49448 Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor
6 6 SCOP 50023 Rieske iron-sulfur protein (ISP)
6 6 SCOP 50495 Prokaryotic proteases
6 6 SCOP 51557 Adenosine/AMP deaminase
6 6 SCOP 51591 Class II FBP aldolase
6 6 SCOP 51736 Alcohol dehydrogenase-like, C-terminal domain
6 6 SCOP 51830 Formate/glycerate dehydrogenases, NAD-domain
6 6 SCOP 52100 Tail specific protease, catalytic domain
6 6 SCOP 56525 Oxidoreductase molybdopterin-binding domain
6 6 SCOP 56673 DNA polymerase I
6 4 SCOP 74753 Catalase-peroxidase KatG
6 6 SCOP 75459 Pseudouridine synthase RsuA/RluD
6 6 SCOP 89125 Nop domain
6 3 SCOP 89572 Biotin dependent carboxylase carboxyltransferase domain
6 6 SCOP 89734 L-sulfolactate dehydrogenase-like
6 6 SCOP 100921 Heat shock protein 70kD (HSP70), peptide-binding domain
6 6 SCOP 140991 FtsH protease domain-like
6 6 SCOP 142721 PyrH-like
5 5 SCOP 47253 Ribonucleotide reductase-like
5 5 SCOP 47502 Calmodulin-like
5 5 SCOP 48226 Class I alpha-1;2-mannosidase, catalytic domain
5 5 SCOP 50277 Myf domain
5 5 SCOP 50448 Elongation factors
5 5 SCOP 51372 D-ribulose-5-phosphate 3-epimerase
5 5 SCOP 51605 Enolase
5 5 SCOP 51696 Mammalian PLC
5 5 SCOP 51727 Uroporphyrinogen decarboxylase, UROD
5 5 SCOP 51868 6-phosphogluconate dehydrogenase-like, N-terminal domain
5 5 SCOP 51883 Aminoacid dehydrogenase-like, C-terminal domain
5 5 SCOP 52670 RecA protein-like (ATPase-domain)
5 5 SCOP 53099 Ribonuclease H
5 5 SCOP 53118 DnaQ-like 3'-5' exonuclease
5 5 SCOP 53701 Phosphoglucose isomerase, PGI
5 5 SCOP 54212 Translational machinery components
5 5 SCOP 54224 DNA gyrase/MutL, second domain
5 3 SCOP 54229 Ribonuclease PH domain 1-like
5 5 SCOP 55308 Tubulin, C-terminal domain
5 5 SCOP 55425 FAD/NAD-linked reductases, dimerisation (C-terminal) domain
5 5 SCOP 55875 Heat shock protein 90, HSP90, N-terminal domain
5 5 SCOP 56720 Type II DNA topoisomerase
5 5 SCOP 56816 Sec1/munc18-like (SM) proteins
5 5 SCOP 64485 RNA-polymerase beta
5 5 SCOP 64490 RNA-polymerase beta-prime
5 5 SCOP 75521 Clathrin coat assembly domain
5 5 SCOP 88766 Branched-chain alpha-keto acid dehydrogenase PP module
5 5 SCOP 118216 Proton glutamate symport protein
5 5 SCOP 159112 RNB domain-like
4 2 SCOP 48243 Terpene synthases
4 4 SCOP 48385 HEAT repeat
4 4 SCOP 48453 Tetratricopeptide repeat (TPR)
4 4 SCOP 48577 Isoprenyl diphosphate synthases
4 4 SCOP 50136 Alcohol dehydrogenase-like, N-terminal domain
4 4 SCOP 50461 Ribosomal protein L3
4 4 SCOP 50476 PNP-oxidase like
4 4 SCOP 51231 Biotinyl/lipoyl-carrier proteins and domains
4 4 SCOP 51247 BC C-terminal domain-like
4 4 SCOP 52022 Carbamoyl phosphate synthetase, small subunit N-terminal domain
4 4 SCOP 52030 GroEL-like chaperone, apical domain
4 4 SCOP 52211 Succinyl-CoA synthetase domains
4 4 SCOP 52219 Flavodoxin-related
4 4 SCOP 52344 Reductases
4 4 SCOP 52419 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
4 4 SCOP 52773 Histone deacetylase, HDAC
4 4 SCOP 52778 CAT-like
4 4 SCOP 52901 Glutathione peroxidase-like
4 2 SCOP 53089 Glycerol kinase
4 4 SCOP 53201 Leucine aminopeptidase, C-terminal domain
4 4 SCOP 53224 Aminoacid dehydrogenases
4 4 SCOP 53351 Arginine methyltransferase
4 4 SCOP 53653 Arylsulfatase
4 4 SCOP 53672 Aspartate/ornithine carbamoyltransferase
4 2 SCOP 53739 Phosphoglucomutase, first 3 domains
4 4 SCOP 53791 Tetrapyrrole methylase
4 4 SCOP 53851 Phosphate binding protein-like
4 4 SCOP 54198 HIT (HINT, histidine triad) family of protein kinase-interacting proteins
4 4 SCOP 54827 Enolase N-terminal domain-like
4 4 SCOP 55323 ERF1/Dom34 C-terminal domain-like
4 4 SCOP 55419 Translation initiation factor eIF4e
4 2 SCOP 55748 N-myristoyl transferase, NMT
4 2 SCOP 55983 DNA polymerase processivity factor
4 4 SCOP 56171 Phoshoinositide 3-kinase (PI3K), catalytic domain
4 4 SCOP 56426 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain
4 4 SCOP 56646 Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains
4 4 SCOP 56753 D-aminoacid aminotransferase-like PLP-dependent enzymes
4 4 SCOP 64006 Undecaprenyl diphosphate synthase
4 4 SCOP 69746 Pseudouridine synthase II TruB
4 4 SCOP 75621 Release factor
4 4 SCOP 82458 Trunk domain of Sec23/24
4 4 SCOP 82583 G domain-linked domain
4 4 SCOP 88714 alpha-mannosidase
4 4 SCOP 88741 Branched-chain alpha-keto acid dehydrogenase Pyr module
4 4 SCOP 100888 Lesion bypass DNA polymerase (Y-family), catalytic domain
4 2 SCOP 101588 Allantoicase repeat
4 4 SCOP 102755 Hsp90 middle domain
4 4 SCOP 111155 Porphyromonas-type peptidylarginine deiminase
4 4 SCOP 143916 RNase Z-like
3 3 SCOP 46549 Fumarate reductase/Succinate dehydogenase iron-sulfur protein, C-terminal domain
3 3 SCOP 46627 monodomain cytochrome c
3 3 SCOP 47204 Medium chain acyl-CoA dehydrogenase-like, C-terminal domain
3 3 SCOP 47955 Cyclin
3 3 SCOP 48246 Protein prenyltransferases
3 3 SCOP 48614 Eukaryotic type heme oxygenase
3 3 SCOP 50307 DNA ligase/mRNA capping enzyme postcatalytic domain
3 3 SCOP 50325 Inorganic pyrophosphatase
3 3 SCOP 50466 EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
3 3 SCOP 50646 Pepsin-like
3 3 SCOP 51381 Tryptophan biosynthesis enzymes
3 3 SCOP 51420 Alanine racemase-like, N-terminal domain
3 3 SCOP 51550 beta-N-acetylhexosaminidase catalytic domain
3 3 SCOP 51629 Pyruvate phosphate dikinase, C-terminal domain
3 3 SCOP 51632 Phosphoenolpyruvate carboxylase
3 3 SCOP 51691 NadC C-terminal domain-like
3 3 SCOP 51848 LDH N-terminal domain-like
3 3 SCOP 52002 R1 subunit of ribonucleotide reductase, C-terminal domain
3 3 SCOP 52142 Uracil-DNA glycosylase
3 3 SCOP 52167 Ribosomal protein L4
3 3 SCOP 52243 Cobalamin (vitamin B12)-binding domain
3 3 SCOP 52484 Transhydrogenase domain III (dIII)
3 3 SCOP 52926 Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain
3 3 SCOP 52944 ATP synthase (F1-ATPase), gamma subunit
3 3 SCOP 53204 Bacterial dinuclear zinc exopeptidases
3 3 SCOP 53329 Formyltransferase
3 3 SCOP 53461 UDP-glucose pyrophosphorylase
3 3 SCOP 53496 Prolyl oligopeptidase, C-terminal domain
3 3 SCOP 53614 Ribokinase-like
3 3 SCOP 53629 Folylpolyglutamate synthetase
3 3 SCOP 53660 Dimeric isocitrate & isopropylmalate dehydrogenases
3 3 SCOP 53733 Aconitase iron-sulfur domain
3 3 SCOP 54232 GHMP Kinase, N-terminal domain
3 3 SCOP 54920 Nucleoside diphosphate kinase, NDK
3 2 SCOP 54981 EF-G/eEF-2 domains III and V
3 3 SCOP 55187 Threonyl-tRNA synthetase (ThrRS), second 'additional' domain
3 3 SCOP 55195 Ribosome recycling factor, RRF
3 2 SCOP 55327 PurM N-terminal domain-like
3 3 SCOP 55363 Homoserine dehydrogenase-like
3 3 SCOP 55368 Dihydrodipicolinate reductase-like
3 3 SCOP 55730 N-acetyl transferase, NAT
3 2 SCOP 56043 PurM C-terminal domain-like
3 3 SCOP 56081 Succinyl-CoA synthetase, beta-chain, N-terminal domain
3 3 SCOP 56307 5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain
3 3 SCOP 56318 Nitrilase
3 3 SCOP 56323 ADC synthase
3 3 SCOP 56328 Lactate & malate dehydrogenases, C-terminal domain
3 3 SCOP 56530 FAH
3 3 SCOP 56713 Prokaryotic type I DNA topoisomerase
3 3 SCOP 56895 Aquaporin-like
3 3 SCOP 57799 Casein kinase II beta subunit
3 3 SCOP 63801 ATP sulfurylase N-terminal domain
3 3 SCOP 63979 ATP sulfurylase catalytic domain
3 3 SCOP 64264 Prokaryotic ribosomal protein L17
3 3 SCOP 69337 Alpha subunit of glutamate synthase, C-terminal domain
3 3 SCOP 69573 Molybdenum cofactor biosynthesis protein MoeB
3 3 SCOP 75633 Cullin homology domain
3 3 SCOP 81630 Poly(A) polymerase, PAP, middle domain
3 3 SCOP 81664 Calcium ATPase, transmembrane domain M
3 3 SCOP 82052 Obg GTP-binding protein N-terminal domain
3 3 SCOP 88704 Phosphoenolpyruvate mutase/Isocitrate lyase-like
3 3 SCOP 88735 TK-like Pyr module
3 3 SCOP 88760 TK-like PP module
3 3 SCOP 89494 HMGL-like
3 3 SCOP 89590 NADPH-dependent FMN reductase
3 3 SCOP 102575 NOL1/NOP2/sun
3 2 SCOP 110384 Cobalamin-independent methionine synthase
3 3 SCOP 110509 NLI interacting factor-like phosphatase
3 2 SCOP 117002 Exportin HEAT-like repeat
3 3 SCOP 118076 TRAPP components
3 3 SCOP 118197 YaeB-like
3 3 SCOP 141840 Class-II DAHP synthetase
3 3 SCOP 142191 5' nucleotidase-like
3 3 SCOP 143906 Gamma-glutamyltranspeptidase-like
2 2 SCOP 46610 Fe,Mn superoxide dismutase (SOD), N-terminal domain
2 2 SCOP 46925 RNA polymerase subunit RPB10
2 2 SCOP 46978 Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain
2 2 SCOP 47324 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
2 2 SCOP 47447 Signal peptide-binding domain
2 2 SCOP 47662 t-snare proteins
2 2 SCOP 47918 C-terminal domain of alpha and beta subunits of F1 ATP synthase
2 1 SCOP 47924 Ypt/Rab-GAP domain of gyp1p
2 2 SCOP 47974 Ribosomal protein S7
2 2 SCOP 48114 CCP-like
2 2 SCOP 48154 Mismatch glycosylase
2 2 SCOP 48180 Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain
2 2 SCOP 48187 HCDH C-domain-like
2 2 SCOP 48390 Clathrin heavy chain proximal leg segment
2 2 SCOP 48393 Clathrin heavy-chain linker domain
2 2 SCOP 48440 Protein prenylyltransferase
2 2 SCOP 48446 14-3-3 protein
2 2 SCOP 48548 PDEase
2 2 SCOP 48580 Squalene synthase
2 2 SCOP 48593 GroEL chaperone, ATPase domain
2 2 SCOP 48604 Allosteric chorismate mutase
2 2 SCOP 49330 Cu,Zn superoxide dismutase-like
2 2 SCOP 49999 Amine oxidase catalytic domain
2 2 SCOP 50114 C-terminal domain of ribosomal protein L2
2 2 SCOP 50183 Sm motif of small nuclear ribonucleoproteins, SNRNP
2 2 SCOP 50282 Cold shock DNA-binding domain-like
2 2 SCOP 50990 Clathrin heavy-chain terminal domain
2 2 SCOP 51168 Galactoside acetyltransferase-like
2 2 SCOP 51413 Inosine monophosphate dehydrogenase (IMPDH)
2 2 SCOP 51427 "Hypothetical" protein ybl036c
2 2 SCOP 51446 Amylase, catalytic domain
2 2 SCOP 51521 Family 1 of glycosyl hydrolase
2 2 SCOP 51553 NagZ-like
2 2 SCOP 51594 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase)
2 2 SCOP 51665 Xylose isomerase
2 2 SCOP 51704 Methylmalonyl-CoA mutase, N-terminal (CoA-binding) domain
2 2 SCOP 51714 tRNA-guanine transglycosylase
2 2 SCOP 51731 Methylenetetrahydrofolate reductase
2 2 SCOP 51931 GDI-like N domain
2 2 SCOP 51934 Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain
2 2 SCOP 51943 FAD/NAD-linked reductases, N-terminal and central domains
2 2 SCOP 52026 PA domain
2 2 SCOP 52034 Group II chaperonin (CCT, TRIC), apical domain
2 2 SCOP 52081 Ribosomal proteins L15p and L18e
2 2 SCOP 52152 FabD-like
2 2 SCOP 52256 N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
2 2 SCOP 52314 Ribosomal protein S2
2 2 SCOP 52432 ETFP subunits
2 2 SCOP 52468 Deoxyhypusine synthase, DHS
2 2 SCOP 52508 Homo-oligomeric flavin-containing Cys decarboxylases, HFCD
2 2 SCOP 52584 Phosphoribulokinase/pantothenate kinase
2 2 SCOP 52589 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain
2 2 SCOP 52769 Arginase-like amidino hydrolases
2 2 SCOP 52895 spliceosomal protein U5-15Kd
2 2 SCOP 52955 Anticodon-binding domain of Class II aaRS
2 2 SCOP 52973 ITPase (Ham1)
2 2 SCOP 53143 ERF1/Dom34 middle domain-like
2 2 SCOP 53183 Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)
2 2 SCOP 53219 MogA-like
2 2 SCOP 53240 Malic enzyme N-domain
2 2 SCOP 53267 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain
2 2 SCOP 53296 Phosphoribosylpyrophosphate synthetase-like
2 2 SCOP 53342 Fibrillarin homologue
2 2 SCOP 53542 Thioesterases
2 2 SCOP 53547 Carboxylesterase/thioesterase 1
2 2 SCOP 53698 double-SIS domain
2 2 SCOP 53796 PEP carboxykinase C-terminal domain
2 2 SCOP 54594 Glyoxalase I (lactoylglutathione lyase)
2 2 SCOP 54632 CBS-domain pair
2 2 SCOP 54687 Ribosomal protein L10e
2 2 SCOP 54714 Elongation factor Ts (EF-Ts), dimerisation domain
2 2 SCOP 54720 Fe,Mn superoxide dismutase (SOD), C-terminal domain
2 2 SCOP 54811 GMP synthetase C-terminal dimerisation domain
2 2 SCOP 55160 eIF1-like
2 2 SCOP 55209 Enolpyruvate transferase, EPT
2 2 SCOP 55283 Ribosomal protein L5
2 2 SCOP 55294 RPB6
2 2 SCOP 55376 Glucose 6-phosphate dehydrogenase-like
2 2 SCOP 55482 N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1
2 2 SCOP 55499 Leishmanolysin
2 2 SCOP 55502 Neutral endopeptidase (neprilysin)
2 2 SCOP 55621 GTP cyclohydrolase I
2 2 SCOP 55625 6-pyruvoyl tetrahydropterin synthase
2 2 SCOP 55638 Cell cycle regulatory proteins
2 2 SCOP 55754 Gelsolin-like
2 2 SCOP 55762 Cofilin-like
2 2 SCOP 55910 Ribosome anti-association factor eIF6 (aIF6)
2 2 SCOP 55932 Glutamine synthetase catalytic domain
2 2 SCOP 55935 Guanido kinase catalytic domain
2 1 SCOP 55946 TATA-box binding protein (TBP), C-terminal domain
2 2 SCOP 56020 The spindle assembly checkpoint protein mad2
2 2 SCOP 56048 Ribosomal protein S8
2 2 SCOP 56085 Pyruvate phosphate dikinase, N-terminal domain
2 2 SCOP 56092 ATP-dependent DNA ligase catalytic domain
2 2 SCOP 56105 SAICAR synthase
2 2 SCOP 56108 Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta
2 2 SCOP 56210 Nitrile hydratase alpha chain
2 2 SCOP 56220 DNase I-like
2 2 SCOP 56277 S-adenosylmethionine decarboxylase
2 2 SCOP 56361 Eukaryotic DNA topoisomerase I, catalytic core
2 2 SCOP 56421 Peptide deformylase
2 2 SCOP 56508 Methionine synthase SAM-binding domain
2 2 SCOP 56535 Aromatic aminoacid monoxygenases, catalytic and oligomerization domains
2 2 SCOP 56543 Substrate-binding domain of HMG-CoA reductase
2 2 SCOP 56727 DNA topoisomerase IV, alpha subunit
2 2 SCOP 56809 Ribosomal protein L1
2 2 SCOP 57663 Ferredoxin thioredoxin reductase (FTR), catalytic beta chain
2 2 SCOP 57851 RING finger domain, C3HC4
2 2 SCOP 63571 PABC (PABP) domain
2 2 SCOP 63611 Pumilio repeat
2 2 SCOP 63738 Leukotriene A4 hydrolase N-terminal domain
2 2 SCOP 63917 Dihydroorotase
2 2 SCOP 63971 Inosicase
2 2 SCOP 63976 Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC)
2 2 SCOP 64136 N-acetylglucosaminyltransferase I
2 2 SCOP 64183 Manganese-dependent inorganic pyrophosphatase (family II)
2 2 SCOP 64198 AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC
2 2 SCOP 64281 Mevalonate 5-diphosphate decarboxylase
2 2 SCOP 64338 Leukotriene A4 hydrolase catalytic domain
2 2 SCOP 64372 3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB
2 2 SCOP 64398 Hsp33 domain
2 2 SCOP 64422 Inositol polyphosphate 5-phosphatase (IPP5)
2 2 SCOP 64511 Phosphoserine phosphatase
2 2 SCOP 68924 PEP carboxykinase N-terminal domain
2 2 SCOP 69210 APC10-like
2 2 SCOP 69341 C-terminal domain of adenylylcyclase associated protein
2 2 SCOP 69427 UDP-galactopyranose mutase, N-terminal domain
2 2 SCOP 69594 Glycerol-3-phosphate (1)-acyltransferase
2 2 SCOP 69602 L-histidinol dehydrogenase HisD
2 2 SCOP 69865 Argininosuccinate synthetase, C-terminal domain
2 2 SCOP 74714 acyl-CoA oxidase C-terminal domains
2 2 SCOP 74756 3-Methyladenine DNA glycosylase I (Tag)
2 2 SCOP 74789 Cullin repeat
2 2 SCOP 74911 Aldose 1-epimerase (mutarotase)
2 2 SCOP 75082 Uronate isomerase-like
2 2 SCOP 75176 D-ribose-5-phosphate isomerase (RpiA), catalytic domain
2 2 SCOP 81652 Calcium ATPase, transduction domain A
2 2 SCOP 81659 Metal cation-transporting ATPase, ATP-binding domain N
2 2 SCOP 81812 Helical domain of Sec23/24
2 2 SCOP 82110 MIR domain
2 2 SCOP 82115 ATP-dependent riboflavin kinase-like
2 2 SCOP 82191 Acireductone dioxygenase
2 2 SCOP 82515 PfkB-like kinase
2 2 SCOP 82540 Trehalose-6-phosphate synthase, OtsA
2 2 SCOP 82545 GckA/TtuD-like
2 2 SCOP 82755 C-terminal, gelsolin-like domain of Sec23/24
2 2 SCOP 82767 Sedlin (SEDL)
2 2 SCOP 88656 alpha-mannosidase, C-terminal domain
2 2 SCOP 88698 PUA domain
2 2 SCOP 88786 C5 cytosine-specific DNA methylase, DCM
2 2 SCOP 89416 gamma-Butyrobetaine hydroxylase
2 2 SCOP 89503 Ketopantoate hydroxymethyltransferase PanB
2 2 SCOP 89763 Ubiquitin activating enzymes (UBA)
2 2 SCOP 89818 Mago nashi protein
2 2 SCOP 90084 Glutaminase
2 2 SCOP 100908 MIF4G domain-like
2 2 SCOP 101153 Mob1/phocein
2 2 SCOP 101340 HD domain
2 2 SCOP 101354 Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
2 2 SCOP 101448 Formin homology 2 domain (FH2 domain)
2 2 SCOP 101536 Coatomer appendage domain
2 2 SCOP 101547 ASF1-like
2 2 SCOP 101888 Apyrase
2 2 SCOP 101984 Pirin-like
2 2 SCOP 102079 Putative alpha-L-fucosidase, catalytic domain
2 2 SCOP 102115 Biotin synthase
2 2 SCOP 102317 NagD-like
2 2 SCOP 102463 Peptidyl-tRNA hydrolase II
2 2 SCOP 102745 mRNA decapping enzyme DcpS C-terminal domain
2 2 SCOP 102769 ATP-dependent protease Lon (La), catalytic domain
2 2 SCOP 102887 Coproporphyrinogen III oxidase
2 2 SCOP 102928 NifU/IscU domain
2 2 SCOP 102945 RelA/SpoT domain
2 2 SCOP 103026 Aminomethyltransferase folate-binding domain
2 2 SCOP 103264 Chorismate synthase, AroC
2 2 SCOP 109613 DAK1
2 2 SCOP 110020 ERO1-like
2 2 SCOP 110112 Ctag/Cox11
2 2 SCOP 110582 Indigoidine synthase A-like
2 2 SCOP 110832 Nip7p homolog, N-terminal domain
2 2 SCOP 111219 ArgJ-like
2 2 SCOP 111233 YfcE-like
2 2 SCOP 117019 ATP-dependent DNA ligase DNA-binding domain
2 2 SCOP 117372 YicI catalytic domain-like
2 2 SCOP 117685 AD-003 protein-like
2 2 SCOP 117714 Hypothetical esterase YJL068C
2 2 SCOP 118204 Vacuolar ATP synthase subunit C
2 2 SCOP 140819 B56-like
2 2 SCOP 140870 GUN4-like
2 2 SCOP 140985 PTPA-like
2 2 SCOP 141436 SSRP1-like
2 2 SCOP 141965 PA1517-like
2 2 SCOP 142186 Enolase-phosphatase E1
2 2 SCOP 142644 RPA4359-like
2 1 SCOP 142678 Glycine dehydrogenase subunits (GDC-P)
2 2 SCOP 142878 Eukaryotic EndoU ribonuclease
2 2 SCOP 143812 GatB/GatE catalytic domain-like
2 2 SCOP 143976 lvD/EDD N-terminal domain-like
2 2 SCOP 144031 Nq06-like
2 2 SCOP 158703 Sec63 N-terminal domain
2 2 SCOP 158737 CPF0428-like
2 2 SCOP 158893 Sec63 C-terminal domain-like
2 2 SCOP 159513 EMG1/NEP1-like
2 2 SCOP 159623 Fumble-like
2 2 SCOP 159638 Prp8 beta-finger domain-like
2 2 SCOP 159697 TRM1-like
2 2 SCOP 159756 O-acetyltransferase
2 2 SCOP 159858 Autophagin-like
2 2 SCOP 160018 PFL3262-like
2 2 SCOP 160921 PSTPO5379-like
1 1 SCOP 46676 Cytochrome bc1 domain
1 1 SCOP 47134 TBP-associated factors, TAFs
1 1 SCOP 47213 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
1 1 SCOP 47577 Calponin-homology domain, CH-domain
1 1 SCOP 47645 Methionine synthase domain
1 1 SCOP 47808 5' to 3' exonuclease, C-terminal subdomain
1 1 SCOP 48184 Acetohydroxy acid isomeroreductase (ketol-acid reductoisomerase, KARI)
1 1 SCOP 48197 Glycerol-3-phosphate dehydrogenase
1 1 SCOP 48257 Citrate synthase
1 1 SCOP 49550 Multidomain cupredoxins
1 1 SCOP 50194 Ribosomal protein L14
1 1 SCOP 50263 Single strand DNA-binding domain, SSB
1 1 SCOP 50616 N-terminal domain of alpha and beta subunits of F1 ATP synthase
1 1 SCOP 50708 Cdc48 N-terminal domain-like
1 1 SCOP 50719 Gln-tRNA synthetase (GlnRS), C-terminal (anticodon-binding) domain
1 1 SCOP 50764 Ran-binding domain
1 1 SCOP 51191 Type I phosphomannose isomerase
1 1 SCOP 51198 Penicillin synthase-like
1 1 SCOP 51279 Urease, beta-subunit
1 1 SCOP 51284 dUTPase-like
1 1 SCOP 51339 alpha-Subunit of urease
1 1 SCOP 51367 Histidine biosynthesis enzymes
1 1 SCOP 51560 alpha-subunit of urease, catalytic domain
1 1 SCOP 51718 Dihydropteroate synthetase
1 1 SCOP 51900 CoA-binding domain
1 1 SCOP 52017 LeuD-like
1 1 SCOP 52122 Lumazine synthase
1 1 SCOP 52162 Ribosomal protein L13
1 1 SCOP 52300 S-adenosylhomocystein hydrolase
1 1 SCOP 52325 DJ-1/PfpI
1 1 SCOP 52426 Cryptochrome/photolyase, N-terminal domain
1 1 SCOP 52471 C-terminal domain of the electron transfer flavoprotein alpha subunit
1 1 SCOP 52575 PAPS sulfotransferase
1 1 SCOP 52734 Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT)
1 1 SCOP 52800 Dual specificity phosphatase-like
1 1 SCOP 52976 Maf-like
1 1 SCOP 53045 5' to 3' exonuclease catalytic domain
1 1 SCOP 53168 Purine and uridine phosphorylases
1 1 SCOP 53509 Proline iminopeptidase-like
1 1 SCOP 53620 Thiamin biosynthesis kinases
1 1 SCOP 53634 Carbamate kinase
1 1 SCOP 53775 Glutaminase/Asparaginase
1 1 SCOP 53785 Phosphofructokinase
1 1 SCOP 53801 Ferrochelatase
1 1 SCOP 53914 Chalcone synthase-like
1 1 SCOP 54044 Transglutaminase core
1 1 SCOP 54050 Ubiquitin carboxyl-terminal hydrolase UCH-L
1 1 SCOP 54054 Adenain-like
1 1 SCOP 54112 Urease, gamma-subunit
1 1 SCOP 54193 L15e
1 1 SCOP 54253 GABARAP-like
1 1 SCOP 54507 Diaminopimelate epimerase
1 1 SCOP 54519 Transcriptional factor tubby, C-terminal domain
1 1 SCOP 54586 Cdc48 domain 2-like
1 1 SCOP 54602 Extradiol dioxygenases
1 1 SCOP 54649 DLC
1 1 SCOP 54696 BTB/POZ domain
1 1 SCOP 54748 Ribosomal L11/L12e N-terminal domain
1 1 SCOP 54792 Eukaryotic type KH-domain (KH-domain type I)
1 1 SCOP 54815 Prokaryotic type KH domain (KH-domain type II)
1 1 SCOP 55032 Bacterial exopeptidase dimerisation domain
1 1 SCOP 55041 Molybdenum cofactor biosynthesis protein C, MoaC
1 1 SCOP 55206 RNA 3'-terminal phosphate cyclase, RPTC
1 1 SCOP 55249 PCD-like
1 1 SCOP 55288 RPB5
1 1 SCOP 55299 YjgF/L-PSP
1 1 SCOP 55316 L30e/L7ae ribosomal proteins
1 1 SCOP 55832 Thymidylate synthase/dCMP hydroxymethylase
1 1 SCOP 55958 Phosphoglucomutase, C-terminal domain
1 1 SCOP 56004 Molybdenum cofactor-binding domain
1 1 SCOP 56088 Eukaryotic glutathione synthetase ATP-binding domain
1 1 SCOP 56187 CO dehydrogenase flavoprotein N-terminal domain-like
1 1 SCOP 56691 T7 RNA polymerase
1 1 SCOP 56742 Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment
1 1 SCOP 63783 Riboflavin synthase
1 1 SCOP 63888 P-domain of calnexin/calreticulin
1 1 SCOP 64154 YjeF N-terminal domain-like
1 1 SCOP 68901 Cytidylytransferase
1 1 SCOP 69001 FAD-dependent thiol oxidase
1 1 SCOP 69236 Calnexin/calreticulin
1 1 SCOP 69565 Pyridoxal-dependent decarboxylase
1 1 SCOP 69766 IpsF-like
1 1 SCOP 69815 Tyrosyl-DNA phosphodiesterase TDP1
1 1 SCOP 74779 Aconitase B, N-terminal domain
1 1 SCOP 74983 Small protein B (SmpB)
1 1 SCOP 75297 N-acetyl-l-glutamate kinase
1 1 SCOP 75600 acyl-CoA oxidase N-terminal domains
1 1 SCOP 81380 Skp1 dimerisation domain-like
1 1 SCOP 81441 Cytochrome c oxidase subunit I-like
1 1 SCOP 81589 Poly(A) polymerase, PAP, N-terminal domain
1 1 SCOP 81768 Pre-protein crosslinking domain of SecA
1 1 SCOP 82283 Homocysteine S-methyltransferase
1 1 SCOP 82388 Predicted hydrolases Cof
1 1 SCOP 82526 Monomeric isocitrate dehydrogenase
1 1 SCOP 88724 Pyruvate oxidase and decarboxylase Pyr module
1 1 SCOP 88749 Pyruvate oxidase and decarboxylase PP module
1 1 SCOP 88784 rRNA adenine dimethylase-like
1 1 SCOP 88947 Sigma2 domain of RNA polymerase sigma factors
1 1 SCOP 89716 XPF/Rad1/Mus81 nuclease
1 1 SCOP 90040 Choline kinase
1 1 SCOP 101392 Hsp90 co-chaperone CDC37
1 1 SCOP 101407 Mo25 protein
1 1 SCOP 101474 DhaL-like
1 1 SCOP 101905 GyrA/ParC C-terminal domain-like
1 1 SCOP 102422 Myotubularin-like phosphatases
1 1 SCOP 102492 CAF1-like ribonuclease
1 1 SCOP 102646 CoaB-like
1 1 SCOP 102959 PG130-like
1 1 SCOP 103011 Galactokinase
1 1 SCOP 103492 Preprotein translocase SecY subunit
1 1 SCOP 110388 MoCo biosynthesis proteins
1 1 SCOP 110436 Ornithine cyclodeaminase-like
1 1 SCOP 110513 IF2B-like
1 1 SCOP 110902 FabZ-like
1 1 SCOP 110994 eIF-2-alpha, C-terminal domain
1 1 SCOP 111338 QueA-like
1 1 SCOP 117917 NifU C-terminal domain-like
1 1 SCOP 140769 MioX-like
1 1 SCOP 141755 PdxS-like
1 1 SCOP 142020 Nqo1 FMN-binding domain-like
1 1 SCOP 142405 NQO2-like
1 1 SCOP 142526 AstE/AspA-like
1 1 SCOP 142867 Phytochelatin synthase
1 1 SCOP 143114 NAP-like
1 1 SCOP 143642 LplA-like
1 1 SCOP 143927 beta-CASP RNA-metabolising hydrolases
1 1 SCOP 143959 Sulfatase-modifying factor-like
1 1 SCOP 158695 UraD-like
1 1 SCOP 159408 Zn-dependent arginine carboxypeptidase-like
1 1 SCOP 159704 SepSecS-like
1 1 SCOP 160880 ADPRibase-Mn-like
1 1 SCOP 161071 SNF-like
1 1 SCOP 161115 PsbO-like

The following families have one or more weak hits: