Family Assignments

Domains Proteins SCOP Link Families
12 10 SCOP 81269 Extended AAA-ATPase domain
11 11 SCOP 52686 ABC transporter ATPase domain-like
10 5 SCOP 81268 Tandem AAA-ATPase domain
9 9 SCOP 55682 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
8 8 SCOP 52375 Class I aminoacyl-tRNA synthetases (RS), catalytic domain
7 7 SCOP 52592 G proteins
5 5 SCOP 52670 RecA protein-like (ATPase-domain)
5 5 SCOP 53417 GABA-aminotransferase-like
5 4 SCOP 56067 BC ATP-binding domain-like
4 4 SCOP 52318 Class I glutamine amidotransferases (GAT)
4 3 SCOP 52441 BC N-terminal domain-like
4 4 SCOP 52652 Nitrogenase iron protein-like
4 2 SCOP 53902 Thiolase-related
3 3 SCOP 48558 L-aspartase/fumarase
3 3 SCOP 50282 Cold shock DNA-binding domain-like
3 3 SCOP 50678 ValRS/IleRS/LeuRS editing domain
3 3 SCOP 51751 Tyrosine-dependent oxidoreductases
3 3 SCOP 52403 N-type ATP pyrophosphatases
3 3 SCOP 52541 Nucleotide and nucleoside kinases
3 3 SCOP 53118 DnaQ-like 3'-5' exonuclease
3 1 SCOP 53739 Phosphoglucomutase, first 3 domains
3 2 SCOP 53914 Chalcone synthase-like
3 2 SCOP 54229 Ribonuclease PH domain 1-like
3 3 SCOP 55425 FAD/NAD-linked reductases, dimerisation (C-terminal) domain
3 3 SCOP 55879 DNA gyrase/MutL, N-terminal domain
2 2 SCOP 47918 C-terminal domain of alpha and beta subunits of F1 ATP synthase
2 2 SCOP 48577 Isoprenyl diphosphate synthases
2 2 SCOP 50448 Elongation factors
2 2 SCOP 50466 EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
2 2 SCOP 51396 FMN-linked oxidoreductases
2 2 SCOP 51570 Class I aldolase
2 2 SCOP 51800 Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
2 2 SCOP 51883 Aminoacid dehydrogenase-like, C-terminal domain
2 2 SCOP 52211 Succinyl-CoA synthetase domains
2 2 SCOP 52432 ETFP subunits
2 2 SCOP 52778 CAT-like
2 1 SCOP 53068 Actin/HSP70
2 2 SCOP 53099 Ribonuclease H
2 2 SCOP 53138 Ribosomal protein L18 and S11
2 2 SCOP 53329 Formyltransferase
2 2 SCOP 53402 Cystathionine synthase-like
2 2 SCOP 53672 Aspartate/ornithine carbamoyltransferase
2 2 SCOP 53851 Phosphate binding protein-like
2 2 SCOP 54212 Translational machinery components
2 2 SCOP 54815 Prokaryotic type KH domain (KH-domain type II)
2 2 SCOP 55209 Enolpyruvate transferase, EPT
2 2 SCOP 55327 PurM N-terminal domain-like
2 2 SCOP 55348 GAPDH-like
2 2 SCOP 55921 Creatinase/aminopeptidase
2 2 SCOP 55932 Glutamine synthetase catalytic domain
2 1 SCOP 55974 S-adenosylmethionine synthetase
2 2 SCOP 56043 PurM C-terminal domain-like
2 2 SCOP 56236 Class II glutamine amidotransferases
2 2 SCOP 56602 beta-Lactamase/D-ala carboxypeptidase
2 2 SCOP 56720 Type II DNA topoisomerase
2 2 SCOP 75621 Release factor
2 2 SCOP 89572 Biotin dependent carboxylase carboxyltransferase domain
2 2 SCOP 89800 Deoxycytidylate deaminase-like
2 2 SCOP 118216 Proton glutamate symport protein
2 2 SCOP 142721 PyrH-like
1 1 SCOP 46549 Fumarate reductase/Succinate dehydogenase iron-sulfur protein, C-terminal domain
1 1 SCOP 46566 Chaperone J-domain
1 1 SCOP 46947 Ribosomal protein S13
1 1 SCOP 47253 Ribonucleotide reductase-like
1 1 SCOP 47324 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
1 1 SCOP 47790 C-terminal domain of RNA polymerase alpha subunit
1 1 SCOP 47974 Ribosomal protein S7
1 1 SCOP 48030 FliG
1 1 SCOP 48109 Carbamoyl phosphate synthetase, large subunit connection domain
1 1 SCOP 48151 Endonuclease III
1 1 SCOP 48174 Cryptochrome/photolyase FAD-binding domain
1 1 SCOP 48180 Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain
1 1 SCOP 48257 Citrate synthase
1 1 SCOP 48335 DNA repair protein MutS, domain III
1 1 SCOP 48593 GroEL chaperone, ATPase domain
1 1 SCOP 49541 Periplasmic domain of cytochrome c oxidase subunit II
1 1 SCOP 50114 C-terminal domain of ribosomal protein L2
1 1 SCOP 50194 Ribosomal protein L14
1 1 SCOP 50263 Single strand DNA-binding domain, SSB
1 1 SCOP 50325 Inorganic pyrophosphatase
1 1 SCOP 50461 Ribosomal protein L3
1 1 SCOP 50476 PNP-oxidase like
1 1 SCOP 50495 Prokaryotic proteases
1 1 SCOP 51165 Tetrahydrodipicolinate-N-succinlytransferase, THDP-succinlytransferase, DapD
1 1 SCOP 51171 GlmU C-terminal domain-like
1 1 SCOP 51247 BC C-terminal domain-like
1 1 SCOP 51284 dUTPase-like
1 1 SCOP 51312 Type 1 signal peptidase
1 1 SCOP 51352 Triosephosphate isomerase (TIM)
1 1 SCOP 51372 D-ribulose-5-phosphate 3-epimerase
1 1 SCOP 51375 Decarboxylase
1 1 SCOP 51413 Inosine monophosphate dehydrogenase (IMPDH)
1 1 SCOP 51420 Alanine racemase-like, N-terminal domain
1 1 SCOP 51594 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase)
1 1 SCOP 51605 Enolase
1 1 SCOP 51622 Pyruvate kinase
1 1 SCOP 51714 tRNA-guanine transglycosylase
1 1 SCOP 51718 Dihydropteroate synthetase
1 1 SCOP 51727 Uroporphyrinogen decarboxylase, UROD
1 1 SCOP 51848 LDH N-terminal domain-like
1 1 SCOP 51868 6-phosphogluconate dehydrogenase-like, N-terminal domain
1 1 SCOP 51900 CoA-binding domain
1 1 SCOP 51913 FAD-linked reductases, N-terminal domain
1 1 SCOP 51934 Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain
1 1 SCOP 51943 FAD/NAD-linked reductases, N-terminal and central domains
1 1 SCOP 51985 MurCD N-terminal domain
1 1 SCOP 52002 R1 subunit of ribonucleotide reductase, C-terminal domain
1 1 SCOP 52017 LeuD-like
1 1 SCOP 52022 Carbamoyl phosphate synthetase, small subunit N-terminal domain
1 1 SCOP 52030 GroEL-like chaperone, apical domain
1 1 SCOP 52081 Ribosomal proteins L15p and L18e
1 1 SCOP 52097 Clp protease, ClpP subunit
1 1 SCOP 52142 Uracil-DNA glycosylase
1 1 SCOP 52152 FabD-like
1 1 SCOP 52162 Ribosomal protein L13
1 1 SCOP 52167 Ribosomal protein L4
1 1 SCOP 52173 CheY-related
1 1 SCOP 52256 N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
1 1 SCOP 52314 Ribosomal protein S2
1 1 SCOP 52344 Reductases
1 1 SCOP 52397 Adenylyltransferase
1 1 SCOP 52426 Cryptochrome/photolyase, N-terminal domain
1 1 SCOP 52471 C-terminal domain of the electron transfer flavoprotein alpha subunit
1 1 SCOP 52491 Tubulin, GTPase domain
1 1 SCOP 52584 Phosphoribulokinase/pantothenate kinase
1 1 SCOP 52901 Glutathione peroxidase-like
1 1 SCOP 52926 Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain
1 1 SCOP 52944 ATP synthase (F1-ATPase), gamma subunit
1 1 SCOP 53045 5' to 3' exonuclease catalytic domain
1 1 SCOP 53057 beta-carbonic anhydrase, cab
1 1 SCOP 53134 RuvC resolvase
1 1 SCOP 53179 Peptidyl-tRNA hydrolase-like
1 1 SCOP 53201 Leucine aminopeptidase, C-terminal domain
1 1 SCOP 53204 Bacterial dinuclear zinc exopeptidases
1 1 SCOP 53240 Malic enzyme N-domain
1 1 SCOP 53255 Cofactor-dependent phosphoglycerate mutase
1 1 SCOP 53272 Phosphoribosyltransferases (PRTases)
1 1 SCOP 53296 Phosphoribosylpyrophosphate synthetase-like
1 1 SCOP 53384 AAT-like
1 1 SCOP 53461 UDP-glucose pyrophosphorylase
1 1 SCOP 53624 MurCDEF
1 1 SCOP 53629 Folylpolyglutamate synthetase
1 1 SCOP 53660 Dimeric isocitrate & isopropylmalate dehydrogenases
1 1 SCOP 53687 Tryptophan synthase beta subunit-like PLP-dependent enzymes
1 1 SCOP 53698 double-SIS domain
1 1 SCOP 53733 Aconitase iron-sulfur domain
1 1 SCOP 53749 Phosphoglycerate kinase
1 1 SCOP 53760 Peptidoglycan biosynthesis glycosyltransferase MurG
1 1 SCOP 53796 PEP carboxykinase C-terminal domain
1 1 SCOP 53801 Ferrochelatase
1 1 SCOP 53811 TroA-like
1 1 SCOP 54224 DNA gyrase/MutL, second domain
1 1 SCOP 54232 GHMP Kinase, N-terminal domain
1 1 SCOP 54632 CBS-domain pair
1 1 SCOP 54641 beta-Hydroxydecanol thiol ester dehydrase
1 1 SCOP 54720 Fe,Mn superoxide dismutase (SOD), C-terminal domain
1 1 SCOP 54811 GMP synthetase C-terminal dimerisation domain
1 1 SCOP 54822 Ribosomal protein S3 C-terminal domain
1 1 SCOP 54827 Enolase N-terminal domain-like
1 1 SCOP 54920 Nucleoside diphosphate kinase, NDK
1 1 SCOP 54981 EF-G/eEF-2 domains III and V
1 1 SCOP 55000 Ribosomal protein S10
1 1 SCOP 55032 Bacterial exopeptidase dimerisation domain
1 1 SCOP 55084 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
1 1 SCOP 55121 Pseudouridine synthase I TruA
1 1 SCOP 55178 Ribosomal protein S4
1 1 SCOP 55187 Threonyl-tRNA synthetase (ThrRS), second 'additional' domain
1 1 SCOP 55195 Ribosome recycling factor, RRF
1 1 SCOP 55272 DNA repair protein MutS, domain I
1 1 SCOP 55283 Ribosomal protein L5
1 1 SCOP 55308 Tubulin, C-terminal domain
1 1 SCOP 55376 Glucose 6-phosphate dehydrogenase-like
1 1 SCOP 55621 GTP cyclohydrolase I
1 1 SCOP 55832 Thymidylate synthase/dCMP hydroxymethylase
1 1 SCOP 55958 Phosphoglucomutase, C-terminal domain
1 1 SCOP 56038 B3/B4 domain of PheRS, PheT
1 1 SCOP 56048 Ribosomal protein S8
1 1 SCOP 56054 Ribosomal protein L6
1 1 SCOP 56060 ATP-binding domain of peptide synthetases
1 1 SCOP 56081 Succinyl-CoA synthetase, beta-chain, N-terminal domain
1 1 SCOP 56096 Adenylation domain of NAD+-dependent DNA ligase
1 1 SCOP 56105 SAICAR synthase
1 1 SCOP 56184 Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase (MurB), N-terminal domain
1 1 SCOP 56195 Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain
1 1 SCOP 56220 DNase I-like
1 1 SCOP 56251 Proteasome subunits
1 1 SCOP 56288 Glyoxalase II (hydroxyacylglutathione hydrolase)
1 1 SCOP 56323 ADC synthase
1 1 SCOP 56328 Lactate & malate dehydrogenases, C-terminal domain
1 1 SCOP 56350 Lambda integrase-like, catalytic core
1 1 SCOP 56421 Peptide deformylase
1 1 SCOP 56426 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain
1 1 SCOP 56543 Substrate-binding domain of HMG-CoA reductase
1 1 SCOP 56554 Insert subdomain of RNA polymerase alpha subunit
1 1 SCOP 56656 Inositol monophosphatase/fructose-1,6-bisphosphatase-like
1 1 SCOP 56673 DNA polymerase I
1 1 SCOP 56713 Prokaryotic type I DNA topoisomerase
1 1 SCOP 56732 DNA primase DnaG catalytic core
1 1 SCOP 56809 Ribosomal protein L1
1 1 SCOP 57939 DnaJ/Hsp40 cysteine-rich domain
1 1 SCOP 63381 Ferredoxin reductase FAD-binding domain-like
1 1 SCOP 63412 MPP-like
1 1 SCOP 63893 Pyridoxine 5'-phosphate synthase
1 1 SCOP 63917 Dihydroorotase
1 1 SCOP 63971 Inosicase
1 1 SCOP 64006 Undecaprenyl diphosphate synthase
1 1 SCOP 64168 SurE-like
1 1 SCOP 64198 AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC
1 1 SCOP 64264 Prokaryotic ribosomal protein L17
1 1 SCOP 64372 3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB
1 1 SCOP 64411 APH phosphotransferases
1 1 SCOP 64485 RNA-polymerase beta
1 1 SCOP 64490 RNA-polymerase beta-prime
1 1 SCOP 68924 PEP carboxykinase N-terminal domain
1 1 SCOP 69865 Argininosuccinate synthetase, C-terminal domain
1 1 SCOP 74732 Ribosomal protein L20
1 1 SCOP 74756 3-Methyladenine DNA glycosylase I (Tag)
1 1 SCOP 74983 Small protein B (SmpB)
1 1 SCOP 75073 Hydantoinase (dihydropyrimidinase), catalytic domain
1 1 SCOP 75297 N-acetyl-l-glutamate kinase
1 1 SCOP 75305 Amidase signature (AS) enzymes
1 1 SCOP 75323 Exonuclease RecJ
1 1 SCOP 75459 Pseudouridine synthase RsuA/RluD
1 1 SCOP 75626 YebC-like
1 1 SCOP 81441 Cytochrome c oxidase subunit I-like
1 1 SCOP 81451 Cytochrome c oxidase subunit III-like
1 1 SCOP 81768 Pre-protein crosslinking domain of SecA
1 1 SCOP 81800 Putative methyltransferase TM0872, insert domain
1 1 SCOP 81887 Helical scaffold and wing domains of SecA
1 1 SCOP 81924 Double Clp-N motif
1 1 SCOP 82052 Obg GTP-binding protein N-terminal domain
1 1 SCOP 82267 TatD Mg-dependent DNase-like
1 1 SCOP 82583 G domain-linked domain
1 1 SCOP 82641 Adaptor protein ClpS (YljA)
1 1 SCOP 88683 Eukaryotic ODC-like
1 1 SCOP 88735 TK-like Pyr module
1 1 SCOP 88741 Branched-chain alpha-keto acid dehydrogenase Pyr module
1 1 SCOP 88760 TK-like PP module
1 1 SCOP 88766 Branched-chain alpha-keto acid dehydrogenase PP module
1 1 SCOP 88784 rRNA adenine dimethylase-like
1 1 SCOP 88786 C5 cytosine-specific DNA methylase, DCM
1 1 SCOP 88947 Sigma2 domain of RNA polymerase sigma factors
1 1 SCOP 89629 tRNA(m1G37)-methyltransferase TrmD
1 1 SCOP 90084 Glutaminase
1 1 SCOP 100921 Heat shock protein 70kD (HSP70), peptide-binding domain
1 1 SCOP 101354 Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
1 1 SCOP 101905 GyrA/ParC C-terminal domain-like
1 1 SCOP 101961 Stabilizer of iron transporter SufD
1 1 SCOP 102115 Biotin synthase
1 1 SCOP 102646 CoaB-like
1 1 SCOP 102656 PdxA-like
1 1 SCOP 102660 PlsX-like
1 1 SCOP 102663 Phosphotransacetylase
1 1 SCOP 102769 ATP-dependent protease Lon (La), catalytic domain
1 1 SCOP 102887 Coproporphyrinogen III oxidase
1 1 SCOP 103264 Chorismate synthase, AroC
1 1 SCOP 109756 PhoU-like
1 1 SCOP 110627 Glucokinase
1 1 SCOP 110902 FabZ-like
1 1 SCOP 110907 Monomeric nicotinate phosphoribosyltransferase N-terminal domain-like
1 1 SCOP 110910 Monomeric nicotinate phosphoribosyltransferase C-terminal domain
1 1 SCOP 111219 ArgJ-like
1 1 SCOP 111305 Recombination protein RecR
1 1 SCOP 111338 QueA-like
1 1 SCOP 117888 Ribosomal protein L16p
1 1 SCOP 140991 FtsH protease domain-like
1 1 SCOP 141245 Ribosomal protein L19
1 1 SCOP 141703 Atu2648/PH1033-like
1 1 SCOP 141723 LON domain-like
1 1 SCOP 142020 Nqo1 FMN-binding domain-like
1 1 SCOP 142644 RPA4359-like
1 1 SCOP 142988 Electron transfer flavoprotein-ubiquinone oxidoreductase-like
1 1 SCOP 143642 LplA-like
1 1 SCOP 143812 GatB/GatE catalytic domain-like
1 1 SCOP 144028 Nqo4-like
1 1 SCOP 144031 Nq06-like
1 1 SCOP 144053 Thermophilic metalloprotease (M29)
1 1 SCOP 158838 AGR C 984p-like
1 1 SCOP 159075 AGR C 3712p-like
1 1 SCOP 159742 Atu1826-like
1 1 SCOP 159832 PBP transglycosylase domain-like
1 1 SCOP 161099 MetI-like

The following families have one or more weak hits: