Family Assignments

Domains Proteins SCOP Link Families
11 7 SCOP 81268 Tandem AAA-ATPase domain
10 10 SCOP 52375 Class I aminoacyl-tRNA synthetases (RS), catalytic domain
10 10 SCOP 55682 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
9 9 SCOP 50282 Cold shock DNA-binding domain-like
9 9 SCOP 52592 G proteins
6 6 SCOP 81269 Extended AAA-ATPase domain
5 5 SCOP 52652 Nitrogenase iron protein-like
4 4 SCOP 52318 Class I glutamine amidotransferases (GAT)
4 4 SCOP 52541 Nucleotide and nucleoside kinases
4 4 SCOP 52670 RecA protein-like (ATPase-domain)
4 2 SCOP 53068 Actin/HSP70
3 3 SCOP 47324 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
3 3 SCOP 47730 Prokaryotic DNA-bending protein
3 2 SCOP 51381 Tryptophan biosynthesis enzymes
3 3 SCOP 51800 Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
3 3 SCOP 52686 ABC transporter ATPase domain-like
3 3 SCOP 53118 DnaQ-like 3'-5' exonuclease
3 3 SCOP 53245 MurCDEF C-terminal domain
3 3 SCOP 53272 Phosphoribosyltransferases (PRTases)
3 3 SCOP 53417 GABA-aminotransferase-like
3 3 SCOP 53624 MurCDEF
3 3 SCOP 53687 Tryptophan synthase beta subunit-like PLP-dependent enzymes
3 3 SCOP 54212 Translational machinery components
2 2 SCOP 48558 L-aspartase/fumarase
2 1 SCOP 48593 GroEL chaperone, ATPase domain
2 2 SCOP 50250 Anticodon-binding domain
2 2 SCOP 50448 Elongation factors
2 2 SCOP 51284 dUTPase-like
2 2 SCOP 51570 Class I aldolase
2 2 SCOP 51751 Tyrosine-dependent oxidoreductases
2 2 SCOP 51883 Aminoacid dehydrogenase-like, C-terminal domain
2 2 SCOP 51943 FAD/NAD-linked reductases, N-terminal and central domains
2 2 SCOP 52397 Adenylyltransferase
2 2 SCOP 52403 N-type ATP pyrophosphatases
2 2 SCOP 52410 PAPS reductase-like
2 1 SCOP 52441 BC N-terminal domain-like
2 2 SCOP 52778 CAT-like
2 2 SCOP 52923 Transketolase C-terminal domain-like
2 1 SCOP 53080 Acetokinase-like
2 2 SCOP 53138 Ribosomal protein L18 and S11
2 2 SCOP 53168 Purine and uridine phosphorylases
2 2 SCOP 53851 Phosphate binding protein-like
2 1 SCOP 53902 Thiolase-related
2 1 SCOP 54229 Ribonuclease PH domain 1-like
2 1 SCOP 54507 Diaminopimelate epimerase
2 2 SCOP 55209 Enolpyruvate transferase, EPT
2 2 SCOP 55348 GAPDH-like
2 2 SCOP 55368 Dihydrodipicolinate reductase-like
2 1 SCOP 56015 Nitrite and sulphite reductase 4Fe-4S domain-like
2 1 SCOP 56054 Ribosomal protein L6
2 2 SCOP 56060 ATP-binding domain of peptide synthetases
2 1 SCOP 56067 BC ATP-binding domain-like
2 1 SCOP 63783 Riboflavin synthase
2 2 SCOP 75459 Pseudouridine synthase RsuA/RluD
2 2 SCOP 75621 Release factor
2 2 SCOP 88735 TK-like Pyr module
2 2 SCOP 88760 TK-like PP module
2 2 SCOP 89800 Deoxycytidylate deaminase-like
2 2 SCOP 100921 Heat shock protein 70kD (HSP70), peptide-binding domain
2 1 SCOP 110384 Cobalamin-independent methionine synthase
2 2 SCOP 142721 PyrH-like
2 2 SCOP 159112 RNB domain-like
1 1 SCOP 46558 GreA transcript cleavage protein, N-terminal domain
1 1 SCOP 46566 Chaperone J-domain
1 1 SCOP 46610 Fe,Mn superoxide dismutase (SOD), N-terminal domain
1 1 SCOP 46912 Ribosomal protein S18
1 1 SCOP 46947 Ribosomal protein S13
1 1 SCOP 46993 Ribosomal protein S20
1 1 SCOP 47064 Ribosomal protein S15
1 1 SCOP 47253 Ribonucleotide reductase-like
1 1 SCOP 47447 Signal peptide-binding domain
1 1 SCOP 47790 C-terminal domain of RNA polymerase alpha subunit
1 1 SCOP 47832 Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
1 1 SCOP 47918 C-terminal domain of alpha and beta subunits of F1 ATP synthase
1 1 SCOP 47974 Ribosomal protein S7
1 1 SCOP 48014 Antitermination factor NusB
1 1 SCOP 48025 N-terminal domain of DnaB helicase
1 1 SCOP 48030 FliG
1 1 SCOP 48109 Carbamoyl phosphate synthetase, large subunit connection domain
1 1 SCOP 48151 Endonuclease III
1 1 SCOP 48154 Mismatch glycosylase
1 1 SCOP 48169 R1 subunit of ribonucleotide reductase, N-terminal domain
1 1 SCOP 48174 Cryptochrome/photolyase FAD-binding domain
1 1 SCOP 48180 Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain
1 1 SCOP 49541 Periplasmic domain of cytochrome c oxidase subunit II
1 1 SCOP 50105 Ribosomal proteins L24p and L21e
1 1 SCOP 50114 C-terminal domain of ribosomal protein L2
1 1 SCOP 50130 GroES
1 1 SCOP 50194 Ribosomal protein L14
1 1 SCOP 50263 Single strand DNA-binding domain, SSB
1 1 SCOP 50325 Inorganic pyrophosphatase
1 1 SCOP 50438 NADPH-cytochrome p450 reductase FAD-binding domain-like
1 1 SCOP 50461 Ribosomal protein L3
1 1 SCOP 50466 EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
1 1 SCOP 50495 Prokaryotic proteases
1 1 SCOP 50678 ValRS/IleRS/LeuRS editing domain
1 1 SCOP 50716 Ribosomal protein L25-like
1 1 SCOP 50719 Gln-tRNA synthetase (GlnRS), C-terminal (anticodon-binding) domain
1 1 SCOP 51165 Tetrahydrodipicolinate-N-succinlytransferase, THDP-succinlytransferase, DapD
1 1 SCOP 51171 GlmU C-terminal domain-like
1 1 SCOP 51262 Glucose permease-like
1 1 SCOP 51312 Type 1 signal peptidase
1 1 SCOP 51345 Epsilon subunit of F1F0-ATP synthase N-terminal domain
1 1 SCOP 51352 Triosephosphate isomerase (TIM)
1 1 SCOP 51367 Histidine biosynthesis enzymes
1 1 SCOP 51372 D-ribulose-5-phosphate 3-epimerase
1 1 SCOP 51375 Decarboxylase
1 1 SCOP 51413 Inosine monophosphate dehydrogenase (IMPDH)
1 1 SCOP 51420 Alanine racemase-like, N-terminal domain
1 1 SCOP 51591 Class II FBP aldolase
1 1 SCOP 51599 Class I DAHP synthetase
1 1 SCOP 51605 Enolase
1 1 SCOP 51622 Pyruvate kinase
1 1 SCOP 51659 Endonuclease IV
1 1 SCOP 51714 tRNA-guanine transglycosylase
1 1 SCOP 51731 Methylenetetrahydrofolate reductase
1 1 SCOP 51868 6-phosphogluconate dehydrogenase-like, N-terminal domain
1 1 SCOP 52002 R1 subunit of ribonucleotide reductase, C-terminal domain
1 1 SCOP 52013 N-terminal domain of enzyme I of the PEP:sugar phosphotransferase system
1 1 SCOP 52022 Carbamoyl phosphate synthetase, small subunit N-terminal domain
1 1 SCOP 52030 GroEL-like chaperone, apical domain
1 1 SCOP 52081 Ribosomal proteins L15p and L18e
1 1 SCOP 52097 Clp protease, ClpP subunit
1 1 SCOP 52122 Lumazine synthase
1 1 SCOP 52142 Uracil-DNA glycosylase
1 1 SCOP 52162 Ribosomal protein L13
1 1 SCOP 52167 Ribosomal protein L4
1 1 SCOP 52219 Flavodoxin-related
1 1 SCOP 52231 Cytochrome p450 reductase N-terminal domain-like
1 1 SCOP 52305 Type II 3-dehydroquinate dehydratase
1 1 SCOP 52314 Ribosomal protein S2
1 1 SCOP 52336 Carbamoyl phosphate synthetase, large subunit allosteric, C-terminal domain
1 1 SCOP 52344 Reductases
1 1 SCOP 52365 NADPH-cytochrome p450 reductase-like
1 1 SCOP 52419 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
1 1 SCOP 52426 Cryptochrome/photolyase, N-terminal domain
1 1 SCOP 52452 D-Alanine ligase N-terminal domain
1 1 SCOP 52457 Prokaryotic glutathione synthetase, N-terminal domain
1 1 SCOP 52475 Pyruvate oxidase and decarboxylase, middle domain
1 1 SCOP 52491 Tubulin, GTPase domain
1 1 SCOP 52566 Shikimate kinase (AroK)
1 1 SCOP 52901 Glutathione peroxidase-like
1 1 SCOP 52944 ATP synthase (F1-ATPase), gamma subunit
1 1 SCOP 52950 Leucine aminopeptidase (Aminopeptidase A), N-terminal domain
1 1 SCOP 52955 Anticodon-binding domain of Class II aaRS
1 1 SCOP 53045 5' to 3' exonuclease catalytic domain
1 1 SCOP 53099 Ribonuclease H
1 1 SCOP 53179 Peptidyl-tRNA hydrolase-like
1 1 SCOP 53201 Leucine aminopeptidase, C-terminal domain
1 1 SCOP 53204 Bacterial dinuclear zinc exopeptidases
1 1 SCOP 53235 Tetrahydrofolate dehydrogenase/cyclohydrolase
1 1 SCOP 53255 Cofactor-dependent phosphoglycerate mutase
1 1 SCOP 53296 Phosphoribosylpyrophosphate synthetase-like
1 1 SCOP 53329 Formyltransferase
1 1 SCOP 53339 RNA methyltransferase FtsJ
1 1 SCOP 53384 AAT-like
1 1 SCOP 53402 Cystathionine synthase-like
1 1 SCOP 53461 UDP-glucose pyrophosphorylase
1 1 SCOP 53598 Dihydrofolate reductases
1 1 SCOP 53629 Folylpolyglutamate synthetase
1 1 SCOP 53660 Dimeric isocitrate & isopropylmalate dehydrogenases
1 1 SCOP 53672 Aspartate/ornithine carbamoyltransferase
1 1 SCOP 53698 double-SIS domain
1 1 SCOP 53701 Phosphoglucose isomerase, PGI
1 1 SCOP 53733 Aconitase iron-sulfur domain
1 1 SCOP 53749 Phosphoglycerate kinase
1 1 SCOP 53760 Peptidoglycan biosynthesis glycosyltransferase MurG
1 1 SCOP 53785 Phosphofructokinase
1 1 SCOP 53791 Tetrapyrrole methylase
1 1 SCOP 54190 L23p
1 1 SCOP 54224 DNA gyrase/MutL, second domain
1 1 SCOP 54232 GHMP Kinase, N-terminal domain
1 1 SCOP 54293 2Fe-2S ferredoxin-related
1 1 SCOP 54535 FKBP immunophilin/proline isomerase
1 1 SCOP 54549 GreA transcript cleavage factor, C-terminal domain
1 1 SCOP 54566 Ribosomal protein S16
1 1 SCOP 54571 Ribosomal protein S19
1 1 SCOP 54612 Bacterial protein-export protein SecB
1 1 SCOP 54638 4HBT-like
1 1 SCOP 54714 Elongation factor Ts (EF-Ts), dimerisation domain
1 1 SCOP 54720 Fe,Mn superoxide dismutase (SOD), C-terminal domain
1 1 SCOP 54737 Ribosomal protein L7/12, C-terminal domain
1 1 SCOP 54748 Ribosomal L11/L12e N-terminal domain
1 1 SCOP 54778 Ribosomal S5 protein, N-terminal domain
1 1 SCOP 54783 Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
1 1 SCOP 54815 Prokaryotic type KH domain (KH-domain type II)
1 1 SCOP 54822 Ribosomal protein S3 C-terminal domain
1 1 SCOP 54827 Enolase N-terminal domain-like
1 1 SCOP 54844 Ribosomal protein L22
1 1 SCOP 54981 EF-G/eEF-2 domains III and V
1 1 SCOP 54996 Ribosomal protein S6
1 1 SCOP 55000 Ribosomal protein S10
1 1 SCOP 55032 Bacterial exopeptidase dimerisation domain
1 1 SCOP 55121 Pseudouridine synthase I TruA
1 1 SCOP 55178 Ribosomal protein S4
1 1 SCOP 55187 Threonyl-tRNA synthetase (ThrRS), second 'additional' domain
1 1 SCOP 55195 Ribosome recycling factor, RRF
1 1 SCOP 55201 Translation initiation factor IF3, C-terminal domain
1 1 SCOP 55258 RNA polymerase alpha subunit dimerisation domain
1 1 SCOP 55283 Ribosomal protein L5
1 1 SCOP 55299 YjgF/L-PSP
1 1 SCOP 55308 Tubulin, C-terminal domain
1 1 SCOP 55363 Homoserine dehydrogenase-like
1 1 SCOP 55376 Glucose 6-phosphate dehydrogenase-like
1 1 SCOP 55425 FAD/NAD-linked reductases, dimerisation (C-terminal) domain
1 1 SCOP 55595 HPr-like
1 1 SCOP 55605 Glucose permease domain IIB
1 1 SCOP 55667 Ribonuclease PH domain 2-like
1 1 SCOP 55805 IIA domain of mannitol-specific and ntr phosphotransferase EII
1 1 SCOP 55822 YrdC-like
1 1 SCOP 55832 Thymidylate synthase/dCMP hydroxymethylase
1 1 SCOP 55875 Heat shock protein 90, HSP90, N-terminal domain
1 1 SCOP 55879 DNA gyrase/MutL, N-terminal domain
1 1 SCOP 55921 Creatinase/aminopeptidase
1 1 SCOP 55980 DNA polymerase III, beta subunit
1 1 SCOP 56048 Ribosomal protein S8
1 1 SCOP 56096 Adenylation domain of NAD+-dependent DNA ligase
1 1 SCOP 56184 Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase (MurB), N-terminal domain
1 1 SCOP 56195 Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain
1 1 SCOP 56236 Class II glutamine amidotransferases
1 1 SCOP 56251 Proteasome subunits
1 1 SCOP 56288 Glyoxalase II (hydroxyacylglutathione hydrolase)
1 1 SCOP 56323 ADC synthase
1 1 SCOP 56421 Peptide deformylase
1 1 SCOP 56554 Insert subdomain of RNA polymerase alpha subunit
1 1 SCOP 56713 Prokaryotic type I DNA topoisomerase
1 1 SCOP 56720 Type II DNA topoisomerase
1 1 SCOP 56732 DNA primase DnaG catalytic core
1 1 SCOP 56797 Dehydroquinate synthase, DHQS
1 1 SCOP 56809 Ribosomal protein L1
1 1 SCOP 56895 Aquaporin-like
1 1 SCOP 56936 Porin
1 1 SCOP 57752 Ribosomal protein S14
1 1 SCOP 57939 DnaJ/Hsp40 cysteine-rich domain
1 1 SCOP 63971 Inosicase
1 1 SCOP 64006 Undecaprenyl diphosphate synthase
1 1 SCOP 64198 AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC
1 1 SCOP 64264 Prokaryotic ribosomal protein L17
1 1 SCOP 64372 3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB
1 1 SCOP 64485 RNA-polymerase beta
1 1 SCOP 64490 RNA-polymerase beta-prime
1 1 SCOP 68901 Cytidylytransferase
1 1 SCOP 69599 mono-SIS domain
1 1 SCOP 69602 L-histidinol dehydrogenase HisD
1 1 SCOP 69746 Pseudouridine synthase II TruB
1 1 SCOP 69766 IpsF-like
1 1 SCOP 69865 Argininosuccinate synthetase, C-terminal domain
1 1 SCOP 74732 Ribosomal protein L20
1 1 SCOP 75170 DsrEF-like
1 1 SCOP 75176 D-ribose-5-phosphate isomerase (RpiA), catalytic domain
1 1 SCOP 75446 D-ribose-5-phosphate isomerase (RpiA), lid domain
1 1 SCOP 75616 Siroheme synthase middle domains-like
1 1 SCOP 81332 F1F0 ATP synthase subunit C
1 1 SCOP 81335 F1F0 ATP synthase subunit A
1 1 SCOP 81441 Cytochrome c oxidase subunit I-like
1 1 SCOP 81451 Cytochrome c oxidase subunit III-like
1 1 SCOP 81463 Cytochrome c oxidase subunit II-like, transmembrane region
1 1 SCOP 81695 Chromosomal replication initiation factor DnaA C-terminal domain IV
1 1 SCOP 81768 Pre-protein crosslinking domain of SecA
1 1 SCOP 81887 Helical scaffold and wing domains of SecA
1 1 SCOP 82052 Obg GTP-binding protein N-terminal domain
1 1 SCOP 82267 TatD Mg-dependent DNase-like
1 1 SCOP 82336 Shikimate dehydrogenase-like
1 1 SCOP 82359 PP-loop ATPase
1 1 SCOP 82509 Biotin biosynthesis protein BioH
1 1 SCOP 82583 G domain-linked domain
1 1 SCOP 82608 YbaB-like
1 1 SCOP 82690 Mechanosensitive channel protein MscS (YggB), C-terminal domain
1 1 SCOP 82862 Mechanosensitive channel protein MscS (YggB), transmembrane region
1 1 SCOP 88665 Sigma4 domain
1 1 SCOP 88683 Eukaryotic ODC-like
1 1 SCOP 88724 Pyruvate oxidase and decarboxylase Pyr module
1 1 SCOP 88749 Pyruvate oxidase and decarboxylase PP module
1 1 SCOP 88784 rRNA adenine dimethylase-like
1 1 SCOP 88851 ATP phosphoribosyltransferase (ATP-PRTase, HisG), regulatory C-terminal domain
1 1 SCOP 88947 Sigma2 domain of RNA polymerase sigma factors
1 1 SCOP 89629 tRNA(m1G37)-methyltransferase TrmD
1 1 SCOP 89632 YggJ C-terminal domain-like
1 1 SCOP 89743 N5-glutamine methyltransferase, HemK
1 1 SCOP 100935 Heat shock protein 70kD (HSP70), C-terminal subdomain
1 1 SCOP 100953 DsbA-like
1 1 SCOP 101354 Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
1 1 SCOP 101905 GyrA/ParC C-terminal domain-like
1 1 SCOP 102115 Biotin synthase
1 1 SCOP 102118 Oxygen-independent coproporphyrinogen III oxidase HemN
1 1 SCOP 102485 Putative Holliday junction resolvase RuvX
1 1 SCOP 102663 Phosphotransacetylase
1 1 SCOP 102706 NIF3 (NGG1p interacting factor 3)-like
1 1 SCOP 102726 Endonuclease I
1 1 SCOP 102755 Hsp90 middle domain
1 1 SCOP 102769 ATP-dependent protease Lon (La), catalytic domain
1 1 SCOP 102928 NifU/IscU domain
1 1 SCOP 103026 Aminomethyltransferase folate-binding domain
1 1 SCOP 103132 Predicted metal-dependent hydrolase
1 1 SCOP 103264 Chorismate synthase, AroC
1 1 SCOP 109636 DnaK suppressor protein DksA, alpha-hairpin domain
1 1 SCOP 110309 Serine acetyltransferase
1 1 SCOP 110325 Ribosomal L27 protein
1 1 SCOP 110902 FabZ-like
1 1 SCOP 110910 Monomeric nicotinate phosphoribosyltransferase C-terminal domain
1 1 SCOP 110943 HSP90 C-terminal domain
1 1 SCOP 111149 YggX-like
1 1 SCOP 111284 Putative modulator of DNA gyrase, PmbA/TldD
1 1 SCOP 111332 NAD kinase-like
1 1 SCOP 117024 DNA primase DnaG, C-terminal domain
1 1 SCOP 117131 CsrA-like
1 1 SCOP 117144 Flagellar hook protein flgE
1 1 SCOP 117619 Exodeoxyribonuclease V beta chain (RecB), C-terminal domain
1 1 SCOP 117622 Exodeoxyribonuclease V beta chain (RecC), C-terminal domain
1 1 SCOP 117888 Ribosomal protein L16p
1 1 SCOP 117992 YbeD-like
1 1 SCOP 118090 Glutamate-cysteine ligase
1 1 SCOP 140991 FtsH protease domain-like
1 1 SCOP 141092 Ribosomal protein L21p
1 1 SCOP 141245 Ribosomal protein L19
1 1 SCOP 141723 LON domain-like
1 1 SCOP 142020 Nqo1 FMN-binding domain-like
1 1 SCOP 142177 Histidinol phosphatase-like
1 1 SCOP 142611 YhhF-like
1 1 SCOP 142696 RibA-like
1 1 SCOP 142735 DeoB catalytic domain-like
1 1 SCOP 143518 TRCF domain
1 1 SCOP 143801 Ribosomal protein L28
1 1 SCOP 143804 Ribosomal protein L31p
1 1 SCOP 143976 lvD/EDD N-terminal domain-like
1 1 SCOP 144028 Nqo4-like
1 1 SCOP 144031 Nq06-like
1 1 SCOP 159195 MLTA-like
1 1 SCOP 159686 YhiQ-like
1 1 SCOP 159832 PBP transglycosylase domain-like

The following families have one or more weak hits: