Family Assignments

Domains Proteins SCOP Link Families
33 31 SCOP 52686 ABC transporter ATPase domain-like
13 13 SCOP 51446 Amylase, catalytic domain
11 7 SCOP 81268 Tandem AAA-ATPase domain
10 8 SCOP 81269 Extended AAA-ATPase domain
9 9 SCOP 53851 Phosphate binding protein-like
8 8 SCOP 52375 Class I aminoacyl-tRNA synthetases (RS), catalytic domain
8 8 SCOP 52592 G proteins
7 7 SCOP 53384 AAT-like
7 7 SCOP 53402 Cystathionine synthase-like
7 7 SCOP 55682 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
6 6 SCOP 51431 Aldo-keto reductases (NADP)
6 6 SCOP 51487 beta-glycanases
6 6 SCOP 53272 Phosphoribosyltransferases (PRTases)
6 5 SCOP 56067 BC ATP-binding domain-like
5 5 SCOP 51396 FMN-linked oxidoreductases
5 5 SCOP 51751 Tyrosine-dependent oxidoreductases
5 5 SCOP 52318 Class I glutamine amidotransferases (GAT)
5 4 SCOP 52441 BC N-terminal domain-like
5 5 SCOP 52652 Nitrogenase iron protein-like
4 4 SCOP 52670 RecA protein-like (ATPase-domain)
4 4 SCOP 53687 Tryptophan synthase beta subunit-like PLP-dependent enzymes
4 4 SCOP 53823 L-arabinose binding protein-like
4 4 SCOP 161099 MetI-like
3 3 SCOP 51830 Formate/glycerate dehydrogenases, NAD-domain
3 3 SCOP 51868 6-phosphogluconate dehydrogenase-like, N-terminal domain
3 3 SCOP 52541 Nucleotide and nucleoside kinases
3 3 SCOP 53591 Nucleoside hydrolase
3 2 SCOP 54229 Ribonuclease PH domain 1-like
3 3 SCOP 55348 GAPDH-like
3 3 SCOP 55368 Dihydrodipicolinate reductase-like
3 1 SCOP 55974 S-adenosylmethionine synthetase
3 3 SCOP 56236 Class II glutamine amidotransferases
3 3 SCOP 56802 Acetyl-CoA synthetase-like
3 3 SCOP 88854 Protein kinases, catalytic subunit
2 2 SCOP 47918 C-terminal domain of alpha and beta subunits of F1 ATP synthase
2 2 SCOP 48558 L-aspartase/fumarase
2 2 SCOP 49803 beta-Galactosidase/glucuronidase, N-terminal domain
2 2 SCOP 50282 Cold shock DNA-binding domain-like
2 2 SCOP 50448 Elongation factors
2 2 SCOP 51168 Galactoside acetyltransferase-like
2 2 SCOP 51284 dUTPase-like
2 2 SCOP 51367 Histidine biosynthesis enzymes
2 2 SCOP 51381 Tryptophan biosynthesis enzymes
2 2 SCOP 51413 Inosine monophosphate dehydrogenase (IMPDH)
2 2 SCOP 51420 Alanine racemase-like, N-terminal domain
2 2 SCOP 51599 Class I DAHP synthetase
2 2 SCOP 51800 Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
2 2 SCOP 52097 Clp protease, ClpP subunit
2 2 SCOP 52173 CheY-related
2 2 SCOP 52211 Succinyl-CoA synthetase domains
2 2 SCOP 52397 Adenylyltransferase
2 2 SCOP 52403 N-type ATP pyrophosphatases
2 2 SCOP 52475 Pyruvate oxidase and decarboxylase, middle domain
2 1 SCOP 53068 Actin/HSP70
2 1 SCOP 53080 Acetokinase-like
2 2 SCOP 53138 Ribosomal protein L18 and S11
2 2 SCOP 53296 Phosphoribosylpyrophosphate synthetase-like
2 2 SCOP 53461 UDP-glucose pyrophosphorylase
2 2 SCOP 53464 glucose-1-phosphate thymidylyltransferase
2 2 SCOP 53620 Thiamin biosynthesis kinases
2 2 SCOP 53660 Dimeric isocitrate & isopropylmalate dehydrogenases
2 2 SCOP 53672 Aspartate/ornithine carbamoyltransferase
2 2 SCOP 53733 Aconitase iron-sulfur domain
2 2 SCOP 54002 Papain-like
2 2 SCOP 54212 Translational machinery components
2 2 SCOP 54815 Prokaryotic type KH domain (KH-domain type II)
2 2 SCOP 55209 Enolpyruvate transferase, EPT
2 1 SCOP 55667 Ribonuclease PH domain 2-like
2 2 SCOP 55879 DNA gyrase/MutL, N-terminal domain
2 2 SCOP 55921 Creatinase/aminopeptidase
2 2 SCOP 55932 Glutamine synthetase catalytic domain
2 2 SCOP 56350 Lambda integrase-like, catalytic core
2 2 SCOP 56421 Peptide deformylase
2 2 SCOP 56720 Type II DNA topoisomerase
2 2 SCOP 69892 Iron-containing alcohol dehydrogenase
2 2 SCOP 75006 alpha-L-arabinanase-like
2 2 SCOP 75218 SpoU-like RNA 2'-O ribose methyltransferase
2 2 SCOP 75621 Release factor
2 2 SCOP 88724 Pyruvate oxidase and decarboxylase Pyr module
2 2 SCOP 88749 Pyruvate oxidase and decarboxylase PP module
2 2 SCOP 89559 NodB-like polysaccharide deacetylase
2 1 SCOP 89572 Biotin dependent carboxylase carboxyltransferase domain
2 2 SCOP 90124 ABC transporter transmembrane region
2 2 SCOP 102945 RelA/SpoT domain
2 1 SCOP 110384 Cobalamin-independent methionine synthase
2 2 SCOP 142721 PyrH-like
2 1 SCOP 143860 Polyphosphate kinase C-terminal domain
2 2 SCOP 159832 PBP transglycosylase domain-like
1 1 SCOP 46947 Ribosomal protein S13
1 1 SCOP 47064 Ribosomal protein S15
1 1 SCOP 47241 Ferritin
1 1 SCOP 47253 Ribonucleotide reductase-like
1 1 SCOP 47324 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
1 1 SCOP 47447 Signal peptide-binding domain
1 1 SCOP 47974 Ribosomal protein S7
1 1 SCOP 48169 R1 subunit of ribonucleotide reductase, N-terminal domain
1 1 SCOP 48180 Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain
1 1 SCOP 48184 Acetohydroxy acid isomeroreductase (ketol-acid reductoisomerase, KARI)
1 1 SCOP 48191 UDP-glucose/GDP-mannose dehydrogenase dimerisation domain
1 1 SCOP 48222 N-acylglucosamine (NAG) epimerase
1 1 SCOP 48257 Citrate synthase
1 1 SCOP 48593 GroEL chaperone, ATPase domain
1 1 SCOP 50114 C-terminal domain of ribosomal protein L2
1 1 SCOP 50130 GroES
1 1 SCOP 50194 Ribosomal protein L14
1 1 SCOP 50263 Single strand DNA-binding domain, SSB
1 1 SCOP 50325 Inorganic pyrophosphatase
1 1 SCOP 50461 Ribosomal protein L3
1 1 SCOP 50466 EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
1 1 SCOP 50495 Prokaryotic proteases
1 1 SCOP 50678 ValRS/IleRS/LeuRS editing domain
1 1 SCOP 50892 Cyclophilin (peptidylprolyl isomerase)
1 1 SCOP 51012 alpha-Amylases, C-terminal beta-sheet domain
1 1 SCOP 51171 GlmU C-terminal domain-like
1 1 SCOP 51183 dTDP-sugar isomerase
1 1 SCOP 51352 Triosephosphate isomerase (TIM)
1 1 SCOP 51372 D-ribulose-5-phosphate 3-epimerase
1 1 SCOP 51392 Thiamin phosphate synthase
1 1 SCOP 51521 Family 1 of glycosyl hydrolase
1 1 SCOP 51553 NagZ-like
1 1 SCOP 51570 Class I aldolase
1 1 SCOP 51591 Class II FBP aldolase
1 1 SCOP 51605 Enolase
1 1 SCOP 51622 Pyruvate kinase
1 1 SCOP 51632 Phosphoenolpyruvate carboxylase
1 1 SCOP 51665 Xylose isomerase
1 1 SCOP 51714 tRNA-guanine transglycosylase
1 1 SCOP 51731 Methylenetetrahydrofolate reductase
1 1 SCOP 51848 LDH N-terminal domain-like
1 1 SCOP 51883 Aminoacid dehydrogenase-like, C-terminal domain
1 1 SCOP 51934 Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain
1 1 SCOP 51999 PFL-like
1 1 SCOP 52002 R1 subunit of ribonucleotide reductase, C-terminal domain
1 1 SCOP 52005 Class III anaerobic ribonucleotide reductase NRDD subunit
1 1 SCOP 52017 LeuD-like
1 1 SCOP 52022 Carbamoyl phosphate synthetase, small subunit N-terminal domain
1 1 SCOP 52030 GroEL-like chaperone, apical domain
1 1 SCOP 52081 Ribosomal proteins L15p and L18e
1 1 SCOP 52142 Uracil-DNA glycosylase
1 1 SCOP 52162 Ribosomal protein L13
1 1 SCOP 52167 Ribosomal protein L4
1 1 SCOP 52256 N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
1 1 SCOP 52284 Formate/glycerate dehydrogenases, substrate-binding domain
1 1 SCOP 52305 Type II 3-dehydroquinate dehydratase
1 1 SCOP 52314 Ribosomal protein S2
1 1 SCOP 52419 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
1 1 SCOP 52484 Transhydrogenase domain III (dIII)
1 1 SCOP 52491 Tubulin, GTPase domain
1 1 SCOP 52901 Glutathione peroxidase-like
1 1 SCOP 52923 Transketolase C-terminal domain-like
1 1 SCOP 52944 ATP synthase (F1-ATPase), gamma subunit
1 1 SCOP 52973 ITPase (Ham1)
1 1 SCOP 53023 Very short patch repair (VSR) endonuclease
1 1 SCOP 53045 5' to 3' exonuclease catalytic domain
1 1 SCOP 53099 Ribonuclease H
1 1 SCOP 53118 DnaQ-like 3'-5' exonuclease
1 1 SCOP 53168 Purine and uridine phosphorylases
1 1 SCOP 53179 Peptidyl-tRNA hydrolase-like
1 1 SCOP 53183 Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)
1 1 SCOP 53204 Bacterial dinuclear zinc exopeptidases
1 1 SCOP 53224 Aminoacid dehydrogenases
1 1 SCOP 53255 Cofactor-dependent phosphoglycerate mutase
1 1 SCOP 53329 Formyltransferase
1 1 SCOP 53417 GABA-aminotransferase-like
1 1 SCOP 53598 Dihydrofolate reductases
1 1 SCOP 53614 Ribokinase-like
1 1 SCOP 53624 MurCDEF
1 1 SCOP 53629 Folylpolyglutamate synthetase
1 1 SCOP 53640 AraD-like aldolase/epimerase
1 1 SCOP 53698 double-SIS domain
1 1 SCOP 53701 Phosphoglucose isomerase, PGI
1 1 SCOP 53721 ALDH-like
1 1 SCOP 53749 Phosphoglycerate kinase
1 1 SCOP 53760 Peptidoglycan biosynthesis glycosyltransferase MurG
1 1 SCOP 53766 Oligosaccharide phosphorylase
1 1 SCOP 54224 DNA gyrase/MutL, second domain
1 1 SCOP 54232 GHMP Kinase, N-terminal domain
1 1 SCOP 54369 Glutamine synthetase, N-terminal domain
1 1 SCOP 54571 Ribosomal protein S19
1 1 SCOP 54811 GMP synthetase C-terminal dimerisation domain
1 1 SCOP 54822 Ribosomal protein S3 C-terminal domain
1 1 SCOP 54827 Enolase N-terminal domain-like
1 1 SCOP 54914 Prokaryotic signal transducing protein
1 1 SCOP 54981 EF-G/eEF-2 domains III and V
1 1 SCOP 55000 Ribosomal protein S10
1 1 SCOP 55069 Peptide methionine sulfoxide reductase
1 1 SCOP 55178 Ribosomal protein S4
1 1 SCOP 55187 Threonyl-tRNA synthetase (ThrRS), second 'additional' domain
1 1 SCOP 55195 Ribosome recycling factor, RRF
1 1 SCOP 55283 Ribosomal protein L5
1 1 SCOP 55299 YjgF/L-PSP
1 1 SCOP 55308 Tubulin, C-terminal domain
1 1 SCOP 55327 PurM N-terminal domain-like
1 1 SCOP 55376 Glucose 6-phosphate dehydrogenase-like
1 1 SCOP 55470 NADH oxidase/flavin reductase
1 1 SCOP 55502 Neutral endopeptidase (neprilysin)
1 1 SCOP 55730 N-acetyl transferase, NAT
1 1 SCOP 55827 YbaK/ProRS associated domain
1 1 SCOP 55832 Thymidylate synthase/dCMP hydroxymethylase
1 1 SCOP 56038 B3/B4 domain of PheRS, PheT
1 1 SCOP 56043 PurM C-terminal domain-like
1 1 SCOP 56048 Ribosomal protein S8
1 1 SCOP 56054 Ribosomal protein L6
1 1 SCOP 56096 Adenylation domain of NAD+-dependent DNA ligase
1 1 SCOP 56105 SAICAR synthase
1 1 SCOP 56248 Penicillin V acylase
1 1 SCOP 56323 ADC synthase
1 1 SCOP 56328 Lactate & malate dehydrogenases, C-terminal domain
1 1 SCOP 56426 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain
1 1 SCOP 56530 FAH
1 1 SCOP 56554 Insert subdomain of RNA polymerase alpha subunit
1 1 SCOP 56673 DNA polymerase I
1 1 SCOP 56713 Prokaryotic type I DNA topoisomerase
1 1 SCOP 56732 DNA primase DnaG catalytic core
1 1 SCOP 56753 D-aminoacid aminotransferase-like PLP-dependent enzymes
1 1 SCOP 56797 Dehydroquinate synthase, DHQS
1 1 SCOP 56809 Ribosomal protein L1
1 1 SCOP 56895 Aquaporin-like
1 1 SCOP 63588 Glycosyltransferase family 36 C-terminal domain
1 1 SCOP 63971 Inosicase
1 1 SCOP 63984 Sir2 family of transcriptional regulators
1 1 SCOP 64006 Undecaprenyl diphosphate synthase
1 1 SCOP 64117 tRNA(1-methyladenosine) methyltransferase-like
1 1 SCOP 64198 AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC
1 1 SCOP 64264 Prokaryotic ribosomal protein L17
1 1 SCOP 64294 Autoinducer-2 production protein LuxS
1 1 SCOP 64485 RNA-polymerase beta
1 1 SCOP 64490 RNA-polymerase beta-prime
1 1 SCOP 64511 Phosphoserine phosphatase
1 1 SCOP 69337 Alpha subunit of glutamate synthase, C-terminal domain
1 1 SCOP 69427 UDP-galactopyranose mutase, N-terminal domain
1 1 SCOP 69501 DTD-like
1 1 SCOP 69560 Mycolic acid cyclopropane synthase
1 1 SCOP 69602 L-histidinol dehydrogenase HisD
1 1 SCOP 69746 Pseudouridine synthase II TruB
1 1 SCOP 69766 IpsF-like
1 1 SCOP 69865 Argininosuccinate synthetase, C-terminal domain
1 1 SCOP 74732 Ribosomal protein L20
1 1 SCOP 74983 Small protein B (SmpB)
1 1 SCOP 75041 SelR domain
1 1 SCOP 75073 Hydantoinase (dihydropyrimidinase), catalytic domain
1 1 SCOP 75297 N-acetyl-l-glutamate kinase
1 1 SCOP 75305 Amidase signature (AS) enzymes
1 1 SCOP 75459 Pseudouridine synthase RsuA/RluD
1 1 SCOP 75626 YebC-like
1 1 SCOP 81605 PP2C-like
1 1 SCOP 81656 Meta-cation ATPase, catalytic domain P
1 1 SCOP 81664 Calcium ATPase, transmembrane domain M
1 1 SCOP 81768 Pre-protein crosslinking domain of SecA
1 1 SCOP 81887 Helical scaffold and wing domains of SecA
1 1 SCOP 82052 Obg GTP-binding protein N-terminal domain
1 1 SCOP 82267 TatD Mg-dependent DNase-like
1 1 SCOP 82371 YbeA-like
1 1 SCOP 82583 G domain-linked domain
1 1 SCOP 82680 N-utilization substance G protein NusG, N-terminal domain
1 1 SCOP 88682 Alanine racemase
1 1 SCOP 88683 Eukaryotic ODC-like
1 1 SCOP 88735 TK-like Pyr module
1 1 SCOP 88760 TK-like PP module
1 1 SCOP 88786 C5 cytosine-specific DNA methylase, DCM
1 1 SCOP 88947 Sigma2 domain of RNA polymerase sigma factors
1 1 SCOP 89494 HMGL-like
1 1 SCOP 89629 tRNA(m1G37)-methyltransferase TrmD
1 1 SCOP 89797 CoA-transferase family III (CaiB/BaiF)
1 1 SCOP 89800 Deoxycytidylate deaminase-like
1 1 SCOP 100888 Lesion bypass DNA polymerase (Y-family), catalytic domain
1 1 SCOP 100921 Heat shock protein 70kD (HSP70), peptide-binding domain
1 1 SCOP 101340 HD domain
1 1 SCOP 101354 Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
1 1 SCOP 101458 TENA/THI-4
1 1 SCOP 101863 Hypothetical protein YodA
1 1 SCOP 101884 Glycosyl hydrolases family 32 N-terminal domain
1 1 SCOP 101905 GyrA/ParC C-terminal domain-like
1 1 SCOP 102317 NagD-like
1 1 SCOP 102406 MoCo carrier protein-like
1 1 SCOP 102663 Phosphotransacetylase
1 1 SCOP 102706 NIF3 (NGG1p interacting factor 3)-like
1 1 SCOP 102928 NifU/IscU domain
1 1 SCOP 103264 Chorismate synthase, AroC
1 1 SCOP 103477 LacY-like proton/sugar symporter
1 1 SCOP 111219 ArgJ-like
1 1 SCOP 111305 Recombination protein RecR
1 1 SCOP 111332 NAD kinase-like
1 1 SCOP 111353 Ammonium transporter
1 1 SCOP 117888 Ribosomal protein L16p
1 1 SCOP 140479 LemA-like
1 1 SCOP 140991 FtsH protease domain-like
1 1 SCOP 141161 Beta-D-xylosidase C-terminal domain-like
1 1 SCOP 141245 Ribosomal protein L19
1 1 SCOP 141331 AraA C-terminal domain-like
1 1 SCOP 141735 HisI-like
1 1 SCOP 141755 PdxS-like
1 1 SCOP 142077 HTS-like
1 1 SCOP 142760 AraA N-terminal and middle domain-like
1 1 SCOP 143549 Serine dehydratase beta chain-like
1 1 SCOP 143812 GatB/GatE catalytic domain-like
1 1 SCOP 143976 lvD/EDD N-terminal domain-like
1 1 SCOP 158600 MgsA/YrvN C-terminal domain-like
1 1 SCOP 159444 SP0239-like
1 1 SCOP 159720 mannose-1-phosphate guanylyl transferase
1 1 SCOP 160370 Ribosomal protein L10-like
1 1 SCOP 160555 TTHA0227-like

The following families have one or more weak hits: