Family Assignments

Domains Proteins SCOP Link Families
38 38 SCOP 52686 ABC transporter ATPase domain-like
14 14 SCOP 53851 Phosphate binding protein-like
12 8 SCOP 81268 Tandem AAA-ATPase domain
12 9 SCOP 81269 Extended AAA-ATPase domain
11 10 SCOP 52592 G proteins
11 11 SCOP 55682 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
9 9 SCOP 52375 Class I aminoacyl-tRNA synthetases (RS), catalytic domain
9 9 SCOP 53272 Phosphoribosyltransferases (PRTases)
6 3 SCOP 53068 Actin/HSP70
5 5 SCOP 52318 Class I glutamine amidotransferases (GAT)
5 5 SCOP 52652 Nitrogenase iron protein-like
5 5 SCOP 53402 Cystathionine synthase-like
4 4 SCOP 50282 Cold shock DNA-binding domain-like
4 4 SCOP 51396 FMN-linked oxidoreductases
4 4 SCOP 51751 Tyrosine-dependent oxidoreductases
4 4 SCOP 51830 Formate/glycerate dehydrogenases, NAD-domain
4 4 SCOP 52541 Nucleotide and nucleoside kinases
4 4 SCOP 52670 RecA protein-like (ATPase-domain)
4 4 SCOP 53204 Bacterial dinuclear zinc exopeptidases
4 2 SCOP 53902 Thiolase-related
4 4 SCOP 55921 Creatinase/aminopeptidase
4 4 SCOP 56602 beta-Lactamase/D-ala carboxypeptidase
3 3 SCOP 48558 L-aspartase/fumarase
3 3 SCOP 50448 Elongation factors
3 3 SCOP 50678 ValRS/IleRS/LeuRS editing domain
3 3 SCOP 51431 Aldo-keto reductases (NADP)
3 3 SCOP 52022 Carbamoyl phosphate synthetase, small subunit N-terminal domain
3 3 SCOP 52584 Phosphoribulokinase/pantothenate kinase
3 3 SCOP 53384 AAT-like
3 3 SCOP 53687 Tryptophan synthase beta subunit-like PLP-dependent enzymes
3 2 SCOP 53914 Chalcone synthase-like
3 3 SCOP 54002 Papain-like
3 3 SCOP 55879 DNA gyrase/MutL, N-terminal domain
3 1 SCOP 55974 S-adenosylmethionine synthetase
3 3 SCOP 56236 Class II glutamine amidotransferases
3 3 SCOP 75459 Pseudouridine synthase RsuA/RluD
3 3 SCOP 82388 Predicted hydrolases Cof
3 3 SCOP 101340 HD domain
3 3 SCOP 102945 RelA/SpoT domain
2 2 SCOP 47324 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
2 2 SCOP 47730 Prokaryotic DNA-bending protein
2 2 SCOP 47918 C-terminal domain of alpha and beta subunits of F1 ATP synthase
2 2 SCOP 51413 Inosine monophosphate dehydrogenase (IMPDH)
2 2 SCOP 51800 Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
2 2 SCOP 51848 LDH N-terminal domain-like
2 2 SCOP 52173 CheY-related
2 2 SCOP 52310 N-deoxyribosyltransferase
2 2 SCOP 52397 Adenylyltransferase
2 2 SCOP 52403 N-type ATP pyrophosphatases
2 2 SCOP 52441 BC N-terminal domain-like
2 1 SCOP 53080 Acetokinase-like
2 2 SCOP 53138 Ribosomal protein L18 and S11
2 2 SCOP 53255 Cofactor-dependent phosphoglycerate mutase
2 2 SCOP 53296 Phosphoribosylpyrophosphate synthetase-like
2 2 SCOP 53329 Formyltransferase
2 2 SCOP 53444 Ornithine decarboxylase major domain
2 2 SCOP 53509 Proline iminopeptidase-like
2 2 SCOP 53591 Nucleoside hydrolase
2 2 SCOP 53614 Ribokinase-like
2 2 SCOP 53629 Folylpolyglutamate synthetase
2 2 SCOP 53785 Phosphofructokinase
2 2 SCOP 54212 Translational machinery components
2 2 SCOP 54224 DNA gyrase/MutL, second domain
2 2 SCOP 54815 Prokaryotic type KH domain (KH-domain type II)
2 1 SCOP 54981 EF-G/eEF-2 domains III and V
2 2 SCOP 55032 Bacterial exopeptidase dimerisation domain
2 2 SCOP 55327 PurM N-terminal domain-like
2 2 SCOP 55348 GAPDH-like
2 2 SCOP 55905 Ornithine decarboxylase C-terminal domain
2 2 SCOP 56043 PurM C-terminal domain-like
2 2 SCOP 56067 BC ATP-binding domain-like
2 2 SCOP 56328 Lactate & malate dehydrogenases, C-terminal domain
2 2 SCOP 56350 Lambda integrase-like, catalytic core
2 2 SCOP 56720 Type II DNA topoisomerase
2 2 SCOP 69427 UDP-galactopyranose mutase, N-terminal domain
2 2 SCOP 69670 UDP-galactopyranose mutase
2 2 SCOP 75218 SpoU-like RNA 2'-O ribose methyltransferase
2 2 SCOP 75621 Release factor
2 2 SCOP 88947 Sigma2 domain of RNA polymerase sigma factors
2 2 SCOP 89572 Biotin dependent carboxylase carboxyltransferase domain
2 2 SCOP 90124 ABC transporter transmembrane region
2 2 SCOP 101905 GyrA/ParC C-terminal domain-like
2 2 SCOP 102575 NOL1/NOP2/sun
2 2 SCOP 142721 PyrH-like
2 1 SCOP 143860 Polyphosphate kinase C-terminal domain
2 2 SCOP 159832 PBP transglycosylase domain-like
2 2 SCOP 161099 MetI-like
1 1 SCOP 46907 Ribosomal protein L11, C-terminal domain
1 1 SCOP 46947 Ribosomal protein S13
1 1 SCOP 47064 Ribosomal protein S15
1 1 SCOP 47786 NAD+-dependent DNA ligase, domain 3
1 1 SCOP 47790 C-terminal domain of RNA polymerase alpha subunit
1 1 SCOP 47974 Ribosomal protein S7
1 1 SCOP 48151 Endonuclease III
1 1 SCOP 48180 Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain
1 1 SCOP 48335 DNA repair protein MutS, domain III
1 1 SCOP 48577 Isoprenyl diphosphate synthases
1 1 SCOP 48593 GroEL chaperone, ATPase domain
1 1 SCOP 49803 beta-Galactosidase/glucuronidase, N-terminal domain
1 1 SCOP 49995 beta-Galactosidase, domain 5
1 1 SCOP 50114 C-terminal domain of ribosomal protein L2
1 1 SCOP 50194 Ribosomal protein L14
1 1 SCOP 50461 Ribosomal protein L3
1 1 SCOP 50466 EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
1 1 SCOP 50490 3-methyladenine DNA glycosylase (AAG, ANPG, MPG)
1 1 SCOP 50495 Prokaryotic proteases
1 1 SCOP 50892 Cyclophilin (peptidylprolyl isomerase)
1 1 SCOP 51171 GlmU C-terminal domain-like
1 1 SCOP 51191 Type I phosphomannose isomerase
1 1 SCOP 51247 BC C-terminal domain-like
1 1 SCOP 51262 Glucose permease-like
1 1 SCOP 51352 Triosephosphate isomerase (TIM)
1 1 SCOP 51372 D-ribulose-5-phosphate 3-epimerase
1 1 SCOP 51375 Decarboxylase
1 1 SCOP 51420 Alanine racemase-like, N-terminal domain
1 1 SCOP 51487 beta-glycanases
1 1 SCOP 51557 Adenosine/AMP deaminase
1 1 SCOP 51591 Class II FBP aldolase
1 1 SCOP 51605 Enolase
1 1 SCOP 51609 D-glucarate dehydratase-like
1 1 SCOP 51622 Pyruvate kinase
1 1 SCOP 51632 Phosphoenolpyruvate carboxylase
1 1 SCOP 51691 NadC C-terminal domain-like
1 1 SCOP 51868 6-phosphogluconate dehydrogenase-like, N-terminal domain
1 1 SCOP 51883 Aminoacid dehydrogenase-like, C-terminal domain
1 1 SCOP 51934 Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain
1 1 SCOP 52005 Class III anaerobic ribonucleotide reductase NRDD subunit
1 1 SCOP 52030 GroEL-like chaperone, apical domain
1 1 SCOP 52081 Ribosomal proteins L15p and L18e
1 1 SCOP 52097 Clp protease, ClpP subunit
1 1 SCOP 52142 Uracil-DNA glycosylase
1 1 SCOP 52162 Ribosomal protein L13
1 1 SCOP 52167 Ribosomal protein L4
1 1 SCOP 52256 N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
1 1 SCOP 52284 Formate/glycerate dehydrogenases, substrate-binding domain
1 1 SCOP 52314 Ribosomal protein S2
1 1 SCOP 52394 Cytidylyltransferase
1 1 SCOP 52475 Pyruvate oxidase and decarboxylase, middle domain
1 1 SCOP 52491 Tubulin, GTPase domain
1 1 SCOP 52513 NagB-like
1 1 SCOP 52729 PTS IIb component
1 1 SCOP 52789 Low-molecular-weight phosphotyrosine protein phosphatases
1 1 SCOP 52944 ATP synthase (F1-ATPase), gamma subunit
1 1 SCOP 52955 Anticodon-binding domain of Class II aaRS
1 1 SCOP 52973 ITPase (Ham1)
1 1 SCOP 53045 5' to 3' exonuclease catalytic domain
1 1 SCOP 53099 Ribonuclease H
1 1 SCOP 53168 Purine and uridine phosphorylases
1 1 SCOP 53179 Peptidyl-tRNA hydrolase-like
1 1 SCOP 53183 Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)
1 1 SCOP 53461 UDP-glucose pyrophosphorylase
1 1 SCOP 53598 Dihydrofolate reductases
1 1 SCOP 53624 MurCDEF
1 1 SCOP 53672 Aspartate/ornithine carbamoyltransferase
1 1 SCOP 53698 double-SIS domain
1 1 SCOP 53701 Phosphoglucose isomerase, PGI
1 1 SCOP 53721 ALDH-like
1 1 SCOP 53749 Phosphoglycerate kinase
1 1 SCOP 53760 Peptidoglycan biosynthesis glycosyltransferase MurG
1 1 SCOP 53763 UDP-N-acetylglucosamine 2-epimerase
1 1 SCOP 53775 Glutaminase/Asparaginase
1 1 SCOP 53823 L-arabinose binding protein-like
1 1 SCOP 53928 Cytidine deaminase
1 1 SCOP 54198 HIT (HINT, histidine triad) family of protein kinase-interacting proteins
1 1 SCOP 54220 RNase P protein
1 1 SCOP 54232 GHMP Kinase, N-terminal domain
1 1 SCOP 54365 Translation initiation factor IF3, N-terminal domain
1 1 SCOP 54535 FKBP immunophilin/proline isomerase
1 1 SCOP 54571 Ribosomal protein S19
1 1 SCOP 54748 Ribosomal L11/L12e N-terminal domain
1 1 SCOP 54822 Ribosomal protein S3 C-terminal domain
1 1 SCOP 54827 Enolase N-terminal domain-like
1 1 SCOP 54844 Ribosomal protein L22
1 1 SCOP 55000 Ribosomal protein S10
1 1 SCOP 55069 Peptide methionine sulfoxide reductase
1 1 SCOP 55084 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
1 1 SCOP 55121 Pseudouridine synthase I TruA
1 1 SCOP 55178 Ribosomal protein S4
1 1 SCOP 55187 Threonyl-tRNA synthetase (ThrRS), second 'additional' domain
1 1 SCOP 55195 Ribosome recycling factor, RRF
1 1 SCOP 55201 Translation initiation factor IF3, C-terminal domain
1 1 SCOP 55209 Enolpyruvate transferase, EPT
1 1 SCOP 55272 DNA repair protein MutS, domain I
1 1 SCOP 55283 Ribosomal protein L5
1 1 SCOP 55308 Tubulin, C-terminal domain
1 1 SCOP 55376 Glucose 6-phosphate dehydrogenase-like
1 1 SCOP 55502 Neutral endopeptidase (neprilysin)
1 1 SCOP 55595 HPr-like
1 1 SCOP 55621 GTP cyclohydrolase I
1 1 SCOP 55782 GAF domain
1 1 SCOP 55817 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain
1 1 SCOP 55822 YrdC-like
1 1 SCOP 55832 Thymidylate synthase/dCMP hydroxymethylase
1 1 SCOP 55932 Glutamine synthetase catalytic domain
1 1 SCOP 56038 B3/B4 domain of PheRS, PheT
1 1 SCOP 56048 Ribosomal protein S8
1 1 SCOP 56054 Ribosomal protein L6
1 1 SCOP 56060 ATP-binding domain of peptide synthetases
1 1 SCOP 56096 Adenylation domain of NAD+-dependent DNA ligase
1 1 SCOP 56105 SAICAR synthase
1 1 SCOP 56184 Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase (MurB), N-terminal domain
1 1 SCOP 56195 Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain
1 1 SCOP 56220 DNase I-like
1 1 SCOP 56251 Proteasome subunits
1 1 SCOP 56421 Peptide deformylase
1 1 SCOP 56426 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain
1 1 SCOP 56520 Penicillin binding protein dimerisation domain
1 1 SCOP 56543 Substrate-binding domain of HMG-CoA reductase
1 1 SCOP 56554 Insert subdomain of RNA polymerase alpha subunit
1 1 SCOP 56673 DNA polymerase I
1 1 SCOP 56713 Prokaryotic type I DNA topoisomerase
1 1 SCOP 56732 DNA primase DnaG catalytic core
1 1 SCOP 56753 D-aminoacid aminotransferase-like PLP-dependent enzymes
1 1 SCOP 56802 Acetyl-CoA synthetase-like
1 1 SCOP 56809 Ribosomal protein L1
1 1 SCOP 56895 Aquaporin-like
1 1 SCOP 57792 DNA primase zinc finger
1 1 SCOP 63912 1,4-beta-N-acetylmuraminidase
1 1 SCOP 63971 Inosicase
1 1 SCOP 63984 Sir2 family of transcriptional regulators
1 1 SCOP 64006 Undecaprenyl diphosphate synthase
1 1 SCOP 64183 Manganese-dependent inorganic pyrophosphatase (family II)
1 1 SCOP 64186 HPr kinase HprK C-terminal domain
1 1 SCOP 64198 AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC
1 1 SCOP 64294 Autoinducer-2 production protein LuxS
1 1 SCOP 64398 Hsp33 domain
1 1 SCOP 64485 RNA-polymerase beta
1 1 SCOP 64490 RNA-polymerase beta-prime
1 1 SCOP 69066 RNase III catalytic domain-like
1 1 SCOP 69501 DTD-like
1 1 SCOP 69518 ArsC-like
1 1 SCOP 69560 Mycolic acid cyclopropane synthase
1 1 SCOP 69581 PepX catalytic domain-like
1 1 SCOP 69706 Transcription factor NusA, N-terminal domain
1 1 SCOP 69746 Pseudouridine synthase II TruB
1 1 SCOP 69912 Clc chloride channel
1 1 SCOP 74732 Ribosomal protein L20
1 1 SCOP 74983 Small protein B (SmpB)
1 1 SCOP 75041 SelR domain
1 1 SCOP 75073 Hydantoinase (dihydropyrimidinase), catalytic domain
1 1 SCOP 75131 B12-dependent (class II) ribonucleotide reductase
1 1 SCOP 75264 Glucose-inhibited division protein B (GidB)
1 1 SCOP 75305 Amidase signature (AS) enzymes
1 1 SCOP 75323 Exonuclease RecJ
1 1 SCOP 75554 Smc hinge domain
1 1 SCOP 75626 YebC-like
1 1 SCOP 81605 PP2C-like
1 1 SCOP 81623 N-terminal domain of MutM-like DNA repair proteins
1 1 SCOP 81656 Meta-cation ATPase, catalytic domain P
1 1 SCOP 81664 Calcium ATPase, transmembrane domain M
1 1 SCOP 81768 Pre-protein crosslinking domain of SecA
1 1 SCOP 81800 Putative methyltransferase TM0872, insert domain
1 1 SCOP 81887 Helical scaffold and wing domains of SecA
1 1 SCOP 81892 Poly A polymerase C-terminal region-like
1 1 SCOP 82052 Obg GTP-binding protein N-terminal domain
1 1 SCOP 82261 N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain
1 1 SCOP 82267 TatD Mg-dependent DNase-like
1 1 SCOP 82336 Shikimate dehydrogenase-like
1 1 SCOP 82371 YbeA-like
1 1 SCOP 82475 MraW-like putative methyltransferases
1 1 SCOP 82550 DegV-like
1 1 SCOP 82583 G domain-linked domain
1 1 SCOP 82661 Poly A polymerase head domain-like
1 1 SCOP 82680 N-utilization substance G protein NusG, N-terminal domain
1 1 SCOP 88682 Alanine racemase
1 1 SCOP 88724 Pyruvate oxidase and decarboxylase Pyr module
1 1 SCOP 88749 Pyruvate oxidase and decarboxylase PP module
1 1 SCOP 88784 rRNA adenine dimethylase-like
1 1 SCOP 88854 Protein kinases, catalytic subunit
1 1 SCOP 89032 Cobalamin adenosyltransferase
1 1 SCOP 89629 tRNA(m1G37)-methyltransferase TrmD
1 1 SCOP 89724 Macro domain
1 1 SCOP 89800 Deoxycytidylate deaminase-like
1 1 SCOP 100888 Lesion bypass DNA polymerase (Y-family), catalytic domain
1 1 SCOP 100921 Heat shock protein 70kD (HSP70), peptide-binding domain
1 1 SCOP 101354 Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
1 1 SCOP 101995 PA3696/SPS0176-like
1 1 SCOP 102317 NagD-like
1 1 SCOP 102485 Putative Holliday junction resolvase RuvX
1 1 SCOP 102646 CoaB-like
1 1 SCOP 102660 PlsX-like
1 1 SCOP 102663 Phosphotransacetylase
1 1 SCOP 102706 NIF3 (NGG1p interacting factor 3)-like
1 1 SCOP 102772 YigZ N-terminal domain-like
1 1 SCOP 102928 NifU/IscU domain
1 1 SCOP 109756 PhoU-like
1 1 SCOP 109965 BC3264-like
1 1 SCOP 110711 Hypothetical protein TT1679
1 1 SCOP 110739 Glycerate kinase I
1 1 SCOP 111305 Recombination protein RecR
1 1 SCOP 111353 Ammonium transporter
1 1 SCOP 117631 RecU-like
1 1 SCOP 117888 Ribosomal protein L16p
1 1 SCOP 140479 LemA-like
1 1 SCOP 140991 FtsH protease domain-like
1 1 SCOP 141092 Ribosomal protein L21p
1 1 SCOP 141245 Ribosomal protein L19
1 1 SCOP 141524 L,D-transpeptidase catalytic domain-like
1 1 SCOP 142093 ThiI-like
1 1 SCOP 142339 CofD-like
1 1 SCOP 142606 N-6 DNA Methylase-like
1 1 SCOP 142611 YhhF-like
1 1 SCOP 142647 TrmB-like
1 1 SCOP 143438 THUMP domain
1 1 SCOP 143473 UTRA domain
1 1 SCOP 143598 YojJ-like
1 1 SCOP 143632 ApbE-like
1 1 SCOP 143812 GatB/GatE catalytic domain-like
1 1 SCOP 143916 RNase Z-like
1 1 SCOP 158600 MgsA/YrvN C-terminal domain-like
1 1 SCOP 159112 RNB domain-like
1 1 SCOP 159444 SP0239-like
1 1 SCOP 159545 SorC sugar-binding domain-like
1 1 SCOP 159579 YpsA-like
1 1 SCOP 159584 PTS system, Fructose specific IIB subunit-like
1 1 SCOP 160984 Diacylglycerol kinase-like

The following families have one or more weak hits: