Family Assignments

Domains Proteins SCOP Link Families
14 14 SCOP 52686 ABC transporter ATPase domain-like
11 7 SCOP 81268 Tandem AAA-ATPase domain
10 10 SCOP 52375 Class I aminoacyl-tRNA synthetases (RS), catalytic domain
10 10 SCOP 55682 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
10 8 SCOP 81269 Extended AAA-ATPase domain
9 9 SCOP 52592 G proteins
8 7 SCOP 52652 Nitrogenase iron protein-like
6 6 SCOP 51751 Tyrosine-dependent oxidoreductases
6 6 SCOP 53417 GABA-aminotransferase-like
5 5 SCOP 52318 Class I glutamine amidotransferases (GAT)
5 3 SCOP 82867 Multidrug efflux transporter AcrB transmembrane domain
4 4 SCOP 54002 Papain-like
3 3 SCOP 50448 Elongation factors
3 3 SCOP 51570 Class I aldolase
3 3 SCOP 51868 6-phosphogluconate dehydrogenase-like, N-terminal domain
3 3 SCOP 51883 Aminoacid dehydrogenase-like, C-terminal domain
3 3 SCOP 52243 Cobalamin (vitamin B12)-binding domain
3 1 SCOP 52484 Transhydrogenase domain III (dIII)
3 3 SCOP 52541 Nucleotide and nucleoside kinases
3 3 SCOP 52901 Glutathione peroxidase-like
3 2 SCOP 53068 Actin/HSP70
3 3 SCOP 53168 Purine and uridine phosphorylases
3 3 SCOP 54535 FKBP immunophilin/proline isomerase
3 3 SCOP 55879 DNA gyrase/MutL, N-terminal domain
3 1 SCOP 55974 S-adenosylmethionine synthetase
3 2 SCOP 56067 BC ATP-binding domain-like
3 3 SCOP 56802 Acetyl-CoA synthetase-like
3 2 SCOP 74656 CoA transferase alpha subunit-like
2 2 SCOP 47204 Medium chain acyl-CoA dehydrogenase-like, C-terminal domain
2 2 SCOP 47241 Ferritin
2 2 SCOP 47324 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
2 2 SCOP 48191 UDP-glucose/GDP-mannose dehydrogenase dimerisation domain
2 2 SCOP 48558 L-aspartase/fumarase
2 2 SCOP 50282 Cold shock DNA-binding domain-like
2 2 SCOP 50678 ValRS/IleRS/LeuRS editing domain
2 2 SCOP 51396 FMN-linked oxidoreductases
2 2 SCOP 51704 Methylmalonyl-CoA mutase, N-terminal (CoA-binding) domain
2 2 SCOP 51943 FAD/NAD-linked reductases, N-terminal and central domains
2 2 SCOP 52100 Tail specific protease, catalytic domain
2 2 SCOP 52103 Crotonase-like
2 2 SCOP 52414 UDP-glucose/GDP-mannose dehydrogenase C-terminal domain
2 1 SCOP 52441 BC N-terminal domain-like
2 2 SCOP 52670 RecA protein-like (ATPase-domain)
2 1 SCOP 53080 Acetokinase-like
2 2 SCOP 53099 Ribonuclease H
2 2 SCOP 53138 Ribosomal protein L18 and S11
2 2 SCOP 53272 Phosphoribosyltransferases (PRTases)
2 2 SCOP 53329 Formyltransferase
2 2 SCOP 53402 Cystathionine synthase-like
2 2 SCOP 53624 MurCDEF
2 2 SCOP 53804 Cobalt chelatase CbiK
2 1 SCOP 53902 Thiolase-related
2 2 SCOP 54212 Translational machinery components
2 1 SCOP 54229 Ribonuclease PH domain 1-like
2 2 SCOP 54815 Prokaryotic type KH domain (KH-domain type II)
2 2 SCOP 54827 Enolase N-terminal domain-like
2 2 SCOP 55209 Enolpyruvate transferase, EPT
2 1 SCOP 55327 PurM N-terminal domain-like
2 2 SCOP 55348 GAPDH-like
2 2 SCOP 55505 Neurolysin-like
2 2 SCOP 55822 YrdC-like
2 2 SCOP 56646 Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains
2 2 SCOP 56713 Prokaryotic type I DNA topoisomerase
2 2 SCOP 56720 Type II DNA topoisomerase
2 2 SCOP 64372 3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB
2 2 SCOP 75621 Release factor
2 2 SCOP 75648 ABC transporter involved in vitamin B12 uptake, BtuC
2 1 SCOP 89572 Biotin dependent carboxylase carboxyltransferase domain
2 2 SCOP 102663 Phosphotransacetylase
2 2 SCOP 111338 QueA-like
2 2 SCOP 140754 PG0816-like
2 1 SCOP 142678 Glycine dehydrogenase subunits (GDC-P)
2 2 SCOP 142721 PyrH-like
2 1 SCOP 143860 Polyphosphate kinase C-terminal domain
1 1 SCOP 46566 Chaperone J-domain
1 1 SCOP 46610 Fe,Mn superoxide dismutase (SOD), N-terminal domain
1 1 SCOP 46947 Ribosomal protein S13
1 1 SCOP 47447 Signal peptide-binding domain
1 1 SCOP 47974 Ribosomal protein S7
1 1 SCOP 48151 Endonuclease III
1 1 SCOP 48154 Mismatch glycosylase
1 1 SCOP 48335 DNA repair protein MutS, domain III
1 1 SCOP 48572 HAL/PAL-like
1 1 SCOP 48577 Isoprenyl diphosphate synthases
1 1 SCOP 48593 GroEL chaperone, ATPase domain
1 1 SCOP 50114 C-terminal domain of ribosomal protein L2
1 1 SCOP 50194 Ribosomal protein L14
1 1 SCOP 50250 Anticodon-binding domain
1 1 SCOP 50461 Ribosomal protein L3
1 1 SCOP 50466 EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
1 1 SCOP 50476 PNP-oxidase like
1 1 SCOP 50495 Prokaryotic proteases
1 1 SCOP 50719 Gln-tRNA synthetase (GlnRS), C-terminal (anticodon-binding) domain
1 1 SCOP 51162 UDP N-acetylglucosamine acyltransferase
1 1 SCOP 51183 dTDP-sugar isomerase
1 1 SCOP 51191 Type I phosphomannose isomerase
1 1 SCOP 51231 Biotinyl/lipoyl-carrier proteins and domains
1 1 SCOP 51284 dUTPase-like
1 1 SCOP 51352 Triosephosphate isomerase (TIM)
1 1 SCOP 51372 D-ribulose-5-phosphate 3-epimerase
1 1 SCOP 51392 Thiamin phosphate synthase
1 1 SCOP 51413 Inosine monophosphate dehydrogenase (IMPDH)
1 1 SCOP 51446 Amylase, catalytic domain
1 1 SCOP 51553 NagZ-like
1 1 SCOP 51599 Class I DAHP synthetase
1 1 SCOP 51605 Enolase
1 1 SCOP 51609 D-glucarate dehydratase-like
1 1 SCOP 51629 Pyruvate phosphate dikinase, C-terminal domain
1 1 SCOP 51659 Endonuclease IV
1 1 SCOP 51691 NadC C-terminal domain-like
1 1 SCOP 51707 Glutamate mutase, large subunit
1 1 SCOP 51714 tRNA-guanine transglycosylase
1 1 SCOP 51718 Dihydropteroate synthetase
1 1 SCOP 51800 Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
1 1 SCOP 51830 Formate/glycerate dehydrogenases, NAD-domain
1 1 SCOP 51913 FAD-linked reductases, N-terminal domain
1 1 SCOP 51934 Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain
1 1 SCOP 52005 Class III anaerobic ribonucleotide reductase NRDD subunit
1 1 SCOP 52010 Pyruvate phosphate dikinase, central domain
1 1 SCOP 52030 GroEL-like chaperone, apical domain
1 1 SCOP 52081 Ribosomal proteins L15p and L18e
1 1 SCOP 52097 Clp protease, ClpP subunit
1 1 SCOP 52122 Lumazine synthase
1 1 SCOP 52142 Uracil-DNA glycosylase
1 1 SCOP 52152 FabD-like
1 1 SCOP 52162 Ribosomal protein L13
1 1 SCOP 52167 Ribosomal protein L4
1 1 SCOP 52219 Flavodoxin-related
1 1 SCOP 52256 N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
1 1 SCOP 52305 Type II 3-dehydroquinate dehydratase
1 1 SCOP 52314 Ribosomal protein S2
1 1 SCOP 52331 Aspartyl dipeptidase PepE
1 1 SCOP 52403 N-type ATP pyrophosphatases
1 1 SCOP 52471 C-terminal domain of the electron transfer flavoprotein alpha subunit
1 1 SCOP 52491 Tubulin, GTPase domain
1 1 SCOP 52513 NagB-like
1 1 SCOP 52584 Phosphoribulokinase/pantothenate kinase
1 1 SCOP 52734 Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT)
1 1 SCOP 52789 Low-molecular-weight phosphotyrosine protein phosphatases
1 1 SCOP 52931 Pyruvate-ferredoxin oxidoreductase, PFOR, domain II
1 1 SCOP 52955 Anticodon-binding domain of Class II aaRS
1 1 SCOP 52973 ITPase (Ham1)
1 1 SCOP 52976 Maf-like
1 1 SCOP 53134 RuvC resolvase
1 1 SCOP 53179 Peptidyl-tRNA hydrolase-like
1 1 SCOP 53183 Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)
1 1 SCOP 53204 Bacterial dinuclear zinc exopeptidases
1 1 SCOP 53224 Aminoacid dehydrogenases
1 1 SCOP 53235 Tetrahydrofolate dehydrogenase/cyclohydrolase
1 1 SCOP 53240 Malic enzyme N-domain
1 1 SCOP 53255 Cofactor-dependent phosphoglycerate mutase
1 1 SCOP 53296 Phosphoribosylpyrophosphate synthetase-like
1 1 SCOP 53324 Pyruvate-ferredoxin oxidoreductase, PFOR, domain III
1 1 SCOP 53397 Beta-eliminating lyases
1 1 SCOP 53464 glucose-1-phosphate thymidylyltransferase
1 1 SCOP 53598 Dihydrofolate reductases
1 1 SCOP 53629 Folylpolyglutamate synthetase
1 1 SCOP 53672 Aspartate/ornithine carbamoyltransferase
1 1 SCOP 53701 Phosphoglucose isomerase, PGI
1 1 SCOP 53749 Phosphoglycerate kinase
1 1 SCOP 53760 Peptidoglycan biosynthesis glycosyltransferase MurG
1 1 SCOP 53775 Glutaminase/Asparaginase
1 1 SCOP 53785 Phosphofructokinase
1 1 SCOP 53791 Tetrapyrrole methylase
1 1 SCOP 53796 PEP carboxykinase C-terminal domain
1 1 SCOP 53851 Phosphate binding protein-like
1 1 SCOP 53914 Chalcone synthase-like
1 1 SCOP 54224 DNA gyrase/MutL, second domain
1 1 SCOP 54571 Ribosomal protein S19
1 1 SCOP 54720 Fe,Mn superoxide dismutase (SOD), C-terminal domain
1 1 SCOP 54748 Ribosomal L11/L12e N-terminal domain
1 1 SCOP 54811 GMP synthetase C-terminal dimerisation domain
1 1 SCOP 54822 Ribosomal protein S3 C-terminal domain
1 1 SCOP 54981 EF-G/eEF-2 domains III and V
1 1 SCOP 55000 Ribosomal protein S10
1 1 SCOP 55069 Peptide methionine sulfoxide reductase
1 1 SCOP 55084 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
1 1 SCOP 55117 Formiminotransferase domain of formiminotransferase-cyclodeaminase.
1 1 SCOP 55121 Pseudouridine synthase I TruA
1 1 SCOP 55178 Ribosomal protein S4
1 1 SCOP 55187 Threonyl-tRNA synthetase (ThrRS), second 'additional' domain
1 1 SCOP 55195 Ribosome recycling factor, RRF
1 1 SCOP 55272 DNA repair protein MutS, domain I
1 1 SCOP 55283 Ribosomal protein L5
1 1 SCOP 55299 YjgF/L-PSP
1 1 SCOP 55368 Dihydrodipicolinate reductase-like
1 1 SCOP 55425 FAD/NAD-linked reductases, dimerisation (C-terminal) domain
1 1 SCOP 55502 Neutral endopeptidase (neprilysin)
1 1 SCOP 55621 GTP cyclohydrolase I
1 1 SCOP 55667 Ribonuclease PH domain 2-like
1 1 SCOP 55832 Thymidylate synthase/dCMP hydroxymethylase
1 1 SCOP 55921 Creatinase/aminopeptidase
1 1 SCOP 56038 B3/B4 domain of PheRS, PheT
1 1 SCOP 56043 PurM C-terminal domain-like
1 1 SCOP 56048 Ribosomal protein S8
1 1 SCOP 56054 Ribosomal protein L6
1 1 SCOP 56085 Pyruvate phosphate dikinase, N-terminal domain
1 1 SCOP 56096 Adenylation domain of NAD+-dependent DNA ligase
1 1 SCOP 56105 SAICAR synthase
1 1 SCOP 56184 Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase (MurB), N-terminal domain
1 1 SCOP 56195 Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain
1 1 SCOP 56323 ADC synthase
1 1 SCOP 56350 Lambda integrase-like, catalytic core
1 1 SCOP 56421 Peptide deformylase
1 1 SCOP 56426 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain
1 1 SCOP 56575 Serpins
1 1 SCOP 56673 DNA polymerase I
1 1 SCOP 56732 DNA primase DnaG catalytic core
1 1 SCOP 56753 D-aminoacid aminotransferase-like PLP-dependent enzymes
1 1 SCOP 56797 Dehydroquinate synthase, DHQS
1 1 SCOP 56809 Ribosomal protein L1
1 1 SCOP 56822 Hybrid cluster protein (prismane protein)
1 1 SCOP 56948 Ligand-gated protein channel
1 1 SCOP 63412 MPP-like
1 1 SCOP 63893 Pyridoxine 5'-phosphate synthase
1 1 SCOP 63966 Precorrin-8X methylmutase CbiC/CobH
1 1 SCOP 63971 Inosicase
1 1 SCOP 63976 Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC)
1 1 SCOP 63984 Sir2 family of transcriptional regulators
1 1 SCOP 64006 Undecaprenyl diphosphate synthase
1 1 SCOP 64168 SurE-like
1 1 SCOP 64198 AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC
1 1 SCOP 64264 Prokaryotic ribosomal protein L17
1 1 SCOP 64485 RNA-polymerase beta
1 1 SCOP 64490 RNA-polymerase beta-prime
1 1 SCOP 64511 Phosphoserine phosphatase
1 1 SCOP 68924 PEP carboxykinase N-terminal domain
1 1 SCOP 69501 DTD-like
1 1 SCOP 69746 Pseudouridine synthase II TruB
1 1 SCOP 69766 IpsF-like
1 1 SCOP 69892 Iron-containing alcohol dehydrogenase
1 1 SCOP 69912 Clc chloride channel
1 1 SCOP 74657 CoA transferase beta subunit-like
1 1 SCOP 74732 Ribosomal protein L20
1 1 SCOP 74983 Small protein B (SmpB)
1 1 SCOP 75041 SelR domain
1 1 SCOP 75073 Hydantoinase (dihydropyrimidinase), catalytic domain
1 1 SCOP 75218 SpoU-like RNA 2'-O ribose methyltransferase
1 1 SCOP 75292 YjeF C-terminal domain-like
1 1 SCOP 75323 Exonuclease RecJ
1 1 SCOP 75459 Pseudouridine synthase RsuA/RluD
1 1 SCOP 75626 YebC-like
1 1 SCOP 82052 Obg GTP-binding protein N-terminal domain
1 1 SCOP 82172 DPP6 N-terminal domain-like
1 1 SCOP 82267 TatD Mg-dependent DNase-like
1 1 SCOP 82475 MraW-like putative methyltransferases
1 1 SCOP 82497 DPP6 catalytic domain-like
1 1 SCOP 82583 G domain-linked domain
1 1 SCOP 82661 Poly A polymerase head domain-like
1 1 SCOP 82749 FemXAB nonribosomal peptidyltransferases
1 1 SCOP 88735 TK-like Pyr module
1 1 SCOP 88746 PFOR Pyr module
1 1 SCOP 88760 TK-like PP module
1 1 SCOP 88771 PFOR PP module
1 1 SCOP 88788 N6 adenine-specific DNA methylase, DAM
1 1 SCOP 88947 Sigma2 domain of RNA polymerase sigma factors
1 1 SCOP 89032 Cobalamin adenosyltransferase
1 1 SCOP 89494 HMGL-like
1 1 SCOP 89503 Ketopantoate hydroxymethyltransferase PanB
1 1 SCOP 89624 Ribose/Galactose isomerase RpiB/AlsB
1 1 SCOP 89629 tRNA(m1G37)-methyltransferase TrmD
1 1 SCOP 89800 Deoxycytidylate deaminase-like
1 1 SCOP 100921 Heat shock protein 70kD (HSP70), peptide-binding domain
1 1 SCOP 101263 Methenyltetrahydrofolate cyclohydrolase-like
1 1 SCOP 101340 HD domain
1 1 SCOP 101354 Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
1 1 SCOP 101905 GyrA/ParC C-terminal domain-like
1 1 SCOP 101961 Stabilizer of iron transporter SufD
1 1 SCOP 102079 Putative alpha-L-fucosidase, catalytic domain
1 1 SCOP 102115 Biotin synthase
1 1 SCOP 102517 N-acetylmuramoyl-L-alanine amidase-like
1 1 SCOP 102581 (Uracil-5-)-methyltransferase
1 1 SCOP 102646 CoaB-like
1 1 SCOP 102656 PdxA-like
1 1 SCOP 102706 NIF3 (NGG1p interacting factor 3)-like
1 1 SCOP 102755 Hsp90 middle domain
1 1 SCOP 102769 ATP-dependent protease Lon (La), catalytic domain
1 1 SCOP 103026 Aminomethyltransferase folate-binding domain
1 1 SCOP 103264 Chorismate synthase, AroC
1 1 SCOP 110396 CutC-like
1 1 SCOP 110400 ThiG-like
1 1 SCOP 110520 Methenyltetrahydrofolate synthetase
1 1 SCOP 111155 Porphyromonas-type peptidylarginine deiminase
1 1 SCOP 111305 Recombination protein RecR
1 1 SCOP 111327 Urocanase
1 1 SCOP 111332 NAD kinase-like
1 1 SCOP 117392 D-lysine 5,6-aminomutase alpha subunit, KamD
1 1 SCOP 117458 FumA C-terminal domain-like
1 1 SCOP 117888 Ribosomal protein L16p
1 1 SCOP 140479 LemA-like
1 1 SCOP 140932 Fic-like
1 1 SCOP 140991 FtsH protease domain-like
1 1 SCOP 141245 Ribosomal protein L19
1 1 SCOP 142635 hypothetical RNA methyltransferase
1 1 SCOP 142696 RibA-like
1 1 SCOP 142755 NadA-like
1 1 SCOP 142824 ComB-like
1 1 SCOP 143598 YojJ-like
1 1 SCOP 143642 LplA-like
1 1 SCOP 143728 PPK middle domain-like
1 1 SCOP 143916 RNase Z-like
1 1 SCOP 158495 PG0775 C-terminal domain-like
1 1 SCOP 158600 MgsA/YrvN C-terminal domain-like
1 1 SCOP 159112 RNB domain-like
1 1 SCOP 159400 Imidazolonepropionase-like
1 1 SCOP 159720 mannose-1-phosphate guanylyl transferase
1 1 SCOP 159832 PBP transglycosylase domain-like
1 1 SCOP 160449 PG1857-like

The following families have one or more weak hits: