Family Assignments

Domains Proteins SCOP Link Families
20 20 SCOP 52686 ABC transporter ATPase domain-like
14 10 SCOP 81269 Extended AAA-ATPase domain
9 9 SCOP 55682 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
8 8 SCOP 52375 Class I aminoacyl-tRNA synthetases (RS), catalytic domain
6 6 SCOP 52318 Class I glutamine amidotransferases (GAT)
6 6 SCOP 52652 Nitrogenase iron protein-like
6 6 SCOP 53687 Tryptophan synthase beta subunit-like PLP-dependent enzymes
5 5 SCOP 52592 G proteins
4 4 SCOP 51751 Tyrosine-dependent oxidoreductases
4 4 SCOP 53384 AAT-like
4 4 SCOP 53417 GABA-aminotransferase-like
4 4 SCOP 53707 Formate dehydrogenase/DMSO reductase, domains 1-3
4 4 SCOP 54632 CBS-domain pair
4 3 SCOP 56067 BC ATP-binding domain-like
4 4 SCOP 56802 Acetyl-CoA synthetase-like
4 3 SCOP 81268 Tandem AAA-ATPase domain
4 4 SCOP 81441 Cytochrome c oxidase subunit I-like
3 3 SCOP 48558 L-aspartase/fumarase
3 3 SCOP 50448 Elongation factors
3 3 SCOP 51396 FMN-linked oxidoreductases
3 3 SCOP 51446 Amylase, catalytic domain
3 3 SCOP 51800 Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
3 3 SCOP 52034 Group II chaperonin (CCT, TRIC), apical domain
3 3 SCOP 52211 Succinyl-CoA synthetase domains
3 3 SCOP 52403 N-type ATP pyrophosphatases
3 3 SCOP 52441 BC N-terminal domain-like
3 3 SCOP 52773 Histone deacetylase, HDAC
3 3 SCOP 52901 Glutathione peroxidase-like
3 3 SCOP 53168 Purine and uridine phosphorylases
3 3 SCOP 53272 Phosphoribosyltransferases (PRTases)
3 3 SCOP 53402 Cystathionine synthase-like
3 3 SCOP 53791 Tetrapyrrole methylase
3 3 SCOP 54161 "Histone-like" proteins from archaea
3 3 SCOP 55921 Creatinase/aminopeptidase
3 3 SCOP 55932 Glutamine synthetase catalytic domain
3 3 SCOP 56004 Molybdenum cofactor-binding domain
3 3 SCOP 56236 Class II glutamine amidotransferases
3 3 SCOP 56251 Proteasome subunits
3 3 SCOP 56713 Prokaryotic type I DNA topoisomerase
2 2 SCOP 48257 Citrate synthase
2 2 SCOP 48596 Group II chaperonin (CCT, TRIC), ATPase domain
2 2 SCOP 50136 Alcohol dehydrogenase-like, N-terminal domain
2 2 SCOP 50282 Cold shock DNA-binding domain-like
2 2 SCOP 50466 EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
2 2 SCOP 50678 ValRS/IleRS/LeuRS editing domain
2 2 SCOP 51231 Biotinyl/lipoyl-carrier proteins and domains
2 2 SCOP 51431 Aldo-keto reductases (NADP)
2 2 SCOP 51570 Class I aldolase
2 2 SCOP 51609 D-glucarate dehydratase-like
2 2 SCOP 51691 NadC C-terminal domain-like
2 2 SCOP 51868 6-phosphogluconate dehydrogenase-like, N-terminal domain
2 2 SCOP 51883 Aminoacid dehydrogenase-like, C-terminal domain
2 2 SCOP 51900 CoA-binding domain
2 2 SCOP 52017 LeuD-like
2 2 SCOP 52670 RecA protein-like (ATPase-domain)
2 2 SCOP 52764 Serine-carboxyl proteinase, SCP
2 2 SCOP 53118 DnaQ-like 3'-5' exonuclease
2 2 SCOP 53204 Bacterial dinuclear zinc exopeptidases
2 2 SCOP 53591 Nucleoside hydrolase
2 2 SCOP 53620 Thiamin biosynthesis kinases
2 2 SCOP 53660 Dimeric isocitrate & isopropylmalate dehydrogenases
2 2 SCOP 53672 Aspartate/ornithine carbamoyltransferase
2 2 SCOP 53698 double-SIS domain
2 2 SCOP 53721 ALDH-like
2 2 SCOP 53733 Aconitase iron-sulfur domain
2 2 SCOP 53851 Phosphate binding protein-like
2 2 SCOP 54229 Ribonuclease PH domain 1-like
2 2 SCOP 54232 GHMP Kinase, N-terminal domain
2 2 SCOP 54874 Archaeal ferredoxins
2 2 SCOP 55348 GAPDH-like
2 2 SCOP 55667 Ribonuclease PH domain 2-like
2 1 SCOP 55946 TATA-box binding protein (TBP), C-terminal domain
2 1 SCOP 55983 DNA polymerase processivity factor
2 2 SCOP 56043 PurM C-terminal domain-like
2 2 SCOP 56220 DNase I-like
2 2 SCOP 56673 DNA polymerase I
2 2 SCOP 63883 MoeA N-terminal region -like
2 2 SCOP 64080 Hjc-like
2 2 SCOP 64490 RNA-polymerase beta-prime
2 2 SCOP 75305 Amidase signature (AS) enzymes
2 2 SCOP 88724 Pyruvate oxidase and decarboxylase Pyr module
2 1 SCOP 89572 Biotin dependent carboxylase carboxyltransferase domain
2 2 SCOP 101340 HD domain
2 2 SCOP 101995 PA3696/SPS0176-like
2 2 SCOP 142678 Glycine dehydrogenase subunits (GDC-P)
2 2 SCOP 142721 PyrH-like
2 2 SCOP 143812 GatB/GatE catalytic domain-like
2 2 SCOP 143927 beta-CASP RNA-metabolising hydrolases
2 2 SCOP 160489 SSO1042-like
2 2 SCOP 160804 PurP ATP-binding domain-like
2 2 SCOP 161099 MetI-like
1 1 SCOP 46610 Fe,Mn superoxide dismutase (SOD), N-terminal domain
1 1 SCOP 47204 Medium chain acyl-CoA dehydrogenase-like, C-terminal domain
1 1 SCOP 47241 Ferritin
1 1 SCOP 47365 Domain of the SRP/SRP receptor G-proteins
1 1 SCOP 47447 Signal peptide-binding domain
1 1 SCOP 47742 CO dehydrogenase ISP C-domain like
1 1 SCOP 47808 5' to 3' exonuclease, C-terminal subdomain
1 1 SCOP 47974 Ribosomal protein S7
1 1 SCOP 48141 Ribosomal protein L19 (L19e)
1 1 SCOP 48184 Acetohydroxy acid isomeroreductase (ketol-acid reductoisomerase, KARI)
1 1 SCOP 48577 Isoprenyl diphosphate synthases
1 1 SCOP 50114 C-terminal domain of ribosomal protein L2
1 1 SCOP 50183 Sm motif of small nuclear ribonucleoproteins, SNRNP
1 1 SCOP 50194 Ribosomal protein L14
1 1 SCOP 50263 Single strand DNA-binding domain, SSB
1 1 SCOP 50277 Myf domain
1 1 SCOP 50307 DNA ligase/mRNA capping enzyme postcatalytic domain
1 1 SCOP 50325 Inorganic pyrophosphatase
1 1 SCOP 50461 Ribosomal protein L3
1 1 SCOP 51174 gamma-carbonic anhydrase-like
1 1 SCOP 51247 BC C-terminal domain-like
1 1 SCOP 51352 Triosephosphate isomerase (TIM)
1 1 SCOP 51367 Histidine biosynthesis enzymes
1 1 SCOP 51381 Tryptophan biosynthesis enzymes
1 1 SCOP 51521 Family 1 of glycosyl hydrolase
1 1 SCOP 51594 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase)
1 1 SCOP 51599 Class I DAHP synthetase
1 1 SCOP 51605 Enolase
1 1 SCOP 51622 Pyruvate kinase
1 1 SCOP 51704 Methylmalonyl-CoA mutase, N-terminal (CoA-binding) domain
1 1 SCOP 51714 tRNA-guanine transglycosylase
1 1 SCOP 51830 Formate/glycerate dehydrogenases, NAD-domain
1 1 SCOP 51934 Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain
1 1 SCOP 52002 R1 subunit of ribonucleotide reductase, C-terminal domain
1 1 SCOP 52022 Carbamoyl phosphate synthetase, small subunit N-terminal domain
1 1 SCOP 52103 Crotonase-like
1 1 SCOP 52147 Mug-like
1 1 SCOP 52157 Initiation factor IF2/eIF5b, domain 3
1 1 SCOP 52162 Ribosomal protein L13
1 1 SCOP 52167 Ribosomal protein L4
1 1 SCOP 52243 Cobalamin (vitamin B12)-binding domain
1 1 SCOP 52256 N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
1 1 SCOP 52300 S-adenosylhomocystein hydrolase
1 1 SCOP 52314 Ribosomal protein S2
1 1 SCOP 52397 Adenylyltransferase
1 1 SCOP 52419 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
1 1 SCOP 52468 Deoxyhypusine synthase, DHS
1 1 SCOP 52471 C-terminal domain of the electron transfer flavoprotein alpha subunit
1 1 SCOP 52508 Homo-oligomeric flavin-containing Cys decarboxylases, HFCD
1 1 SCOP 52541 Nucleotide and nucleoside kinases
1 1 SCOP 52769 Arginase-like amidino hydrolases
1 1 SCOP 52973 ITPase (Ham1)
1 1 SCOP 53045 5' to 3' exonuclease catalytic domain
1 1 SCOP 53099 Ribonuclease H
1 1 SCOP 53138 Ribosomal protein L18 and S11
1 1 SCOP 53224 Aminoacid dehydrogenases
1 1 SCOP 53240 Malic enzyme N-domain
1 1 SCOP 53342 Fibrillarin homologue
1 1 SCOP 53354 Protein-L-isoaspartyl O-methyltransferase
1 1 SCOP 53496 Prolyl oligopeptidase, C-terminal domain
1 1 SCOP 53614 Ribokinase-like
1 1 SCOP 53749 Phosphoglycerate kinase
1 1 SCOP 53775 Glutaminase/Asparaginase
1 1 SCOP 53902 Thiolase-related
1 1 SCOP 54193 L15e
1 1 SCOP 54212 Translational machinery components
1 1 SCOP 54224 DNA gyrase/MutL, second domain
1 1 SCOP 54535 FKBP immunophilin/proline isomerase
1 1 SCOP 54676 NadC N-terminal domain-like
1 1 SCOP 54687 Ribosomal protein L10e
1 1 SCOP 54720 Fe,Mn superoxide dismutase (SOD), C-terminal domain
1 1 SCOP 54792 Eukaryotic type KH-domain (KH-domain type I)
1 1 SCOP 54827 Enolase N-terminal domain-like
1 1 SCOP 54894 Aspartate carbamoyltransferase, Regulatory-chain, N-terminal domain
1 1 SCOP 54920 Nucleoside diphosphate kinase, NDK
1 1 SCOP 55041 Molybdenum cofactor biosynthesis protein C, MoaC
1 1 SCOP 55206 RNA 3'-terminal phosphate cyclase, RPTC
1 1 SCOP 55209 Enolpyruvate transferase, EPT
1 1 SCOP 55262 GAD domain
1 1 SCOP 55283 Ribosomal protein L5
1 1 SCOP 55299 YjgF/L-PSP
1 1 SCOP 55316 L30e/L7ae ribosomal proteins
1 1 SCOP 55327 PurM N-terminal domain-like
1 1 SCOP 55368 Dihydrodipicolinate reductase-like
1 1 SCOP 55505 Neurolysin-like
1 1 SCOP 55621 GTP cyclohydrolase I
1 1 SCOP 55822 YrdC-like
1 1 SCOP 55879 DNA gyrase/MutL, N-terminal domain
1 1 SCOP 55910 Ribosome anti-association factor eIF6 (aIF6)
1 1 SCOP 56048 Ribosomal protein S8
1 1 SCOP 56092 ATP-dependent DNA ligase catalytic domain
1 1 SCOP 56105 SAICAR synthase
1 1 SCOP 56187 CO dehydrogenase flavoprotein N-terminal domain-like
1 1 SCOP 56261 (Glycosyl)asparaginase
1 1 SCOP 56310 Protein serine/threonine phosphatase
1 1 SCOP 56323 ADC synthase
1 1 SCOP 56426 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain
1 1 SCOP 56530 FAH
1 1 SCOP 56543 Substrate-binding domain of HMG-CoA reductase
1 1 SCOP 56646 Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains
1 1 SCOP 56727 DNA topoisomerase IV, alpha subunit
1 1 SCOP 56748 PriA-like
1 1 SCOP 56797 Dehydroquinate synthase, DHQS
1 1 SCOP 56809 Ribosomal protein L1
1 1 SCOP 63830 SGL-like
1 1 SCOP 63966 Precorrin-8X methylmutase CbiC/CobH
1 1 SCOP 63984 Sir2 family of transcriptional regulators
1 1 SCOP 64006 Undecaprenyl diphosphate synthase
1 1 SCOP 64117 tRNA(1-methyladenosine) methyltransferase-like
1 1 SCOP 64372 3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB
1 1 SCOP 64485 RNA-polymerase beta
1 1 SCOP 69557 Spermidine synthase
1 1 SCOP 69599 mono-SIS domain
1 1 SCOP 69602 L-histidinol dehydrogenase HisD
1 1 SCOP 69746 Pseudouridine synthase II TruB
1 1 SCOP 69797 Thymidylate synthase-complementing protein Thy1
1 1 SCOP 69820 MTH1598-like
1 1 SCOP 69865 Argininosuccinate synthetase, C-terminal domain
1 1 SCOP 69912 Clc chloride channel
1 1 SCOP 75292 YjeF C-terminal domain-like
1 1 SCOP 75297 N-acetyl-l-glutamate kinase
1 1 SCOP 75434 Divalent ion tolerance proteins CutA (CutA1)
1 1 SCOP 75648 ABC transporter involved in vitamin B12 uptake, BtuC
1 1 SCOP 81642 Cytochrome b of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
1 1 SCOP 82261 N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain
1 1 SCOP 82267 TatD Mg-dependent DNase-like
1 1 SCOP 82545 GckA/TtuD-like
1 1 SCOP 82705 DNA-binding protein AlbA
1 1 SCOP 88749 Pyruvate oxidase and decarboxylase PP module
1 1 SCOP 89022 HEPN domain
1 1 SCOP 89032 Cobalamin adenosyltransferase
1 1 SCOP 89125 Nop domain
1 1 SCOP 89503 Ketopantoate hydroxymethyltransferase PanB
1 1 SCOP 89716 XPF/Rad1/Mus81 nuclease
1 1 SCOP 89724 Macro domain
1 1 SCOP 89734 L-sulfolactate dehydrogenase-like
1 1 SCOP 90124 ABC transporter transmembrane region
1 1 SCOP 100880 Lesion bypass DNA polymerase (Y-family), little finger domain
1 1 SCOP 100888 Lesion bypass DNA polymerase (Y-family), catalytic domain
1 1 SCOP 100948 Isochorismatase-like hydrolases
1 1 SCOP 101425 Hypothetical protein ST1625
1 1 SCOP 101458 TENA/THI-4
1 1 SCOP 101984 Pirin-like
1 1 SCOP 102199 Putative cyclase
1 1 SCOP 102317 NagD-like
1 1 SCOP 102463 Peptidyl-tRNA hydrolase II
1 1 SCOP 102575 NOL1/NOP2/sun
1 1 SCOP 102646 CoaB-like
1 1 SCOP 103026 Aminomethyltransferase folate-binding domain
1 1 SCOP 103051 AlaX-like
1 1 SCOP 103166 Ta1353-like
1 1 SCOP 103264 Chorismate synthase, AroC
1 1 SCOP 103281 Lysine biosynthesis enzyme LysX ATP-binding domain
1 1 SCOP 103366 Hypothetical protein PH1602
1 1 SCOP 103492 Preprotein translocase SecY subunit
1 1 SCOP 110384 Cobalamin-independent methionine synthase
1 1 SCOP 110388 MoCo biosynthesis proteins
1 1 SCOP 110436 Ornithine cyclodeaminase-like
1 1 SCOP 110513 IF2B-like
1 1 SCOP 111039 YjbQ-like
1 1 SCOP 111250 Sulfolobus fructose-1,6-bisphosphatase-like
1 1 SCOP 111279 SSo0622-like
1 1 SCOP 111343 CbiD-like
1 1 SCOP 111353 Ammonium transporter
1 1 SCOP 116743 eIF2alpha middle domain-like
1 1 SCOP 116993 MazG-like
1 1 SCOP 140915 PriB N-terminal domain-like
1 1 SCOP 141368 UbiD middle domain-like
1 1 SCOP 141735 HisI-like
1 1 SCOP 141755 PdxS-like
1 1 SCOP 142536 AF0625-like
1 1 SCOP 142755 NadA-like
1 1 SCOP 143278 SOR-like
1 1 SCOP 143431 TTP0101/SSO1404-like
1 1 SCOP 143448 AMMECR1-like
1 1 SCOP 143642 LplA-like
1 1 SCOP 143906 Gamma-glutamyltranspeptidase-like
1 1 SCOP 143916 RNase Z-like
1 1 SCOP 143969 UbiD C-terminal domain-like
1 1 SCOP 143976 lvD/EDD N-terminal domain-like
1 1 SCOP 144028 Nqo4-like
1 1 SCOP 144031 Nq06-like
1 1 SCOP 158338 Rps19E-like
1 1 SCOP 158706 Achaeal helicase C-terminal domain
1 1 SCOP 159031 Ribosomal protein L14e
1 1 SCOP 159444 SP0239-like
1 1 SCOP 159513 EMG1/NEP1-like
1 1 SCOP 159665 CobE/GbiG C-terminal domain-like
1 1 SCOP 159673 CbiG N-terminal domain-like
1 1 SCOP 159697 TRM1-like
1 1 SCOP 159768 Phosphomethylpyrimidine kinase C-terminal domain-like
1 1 SCOP 160976 AF1531-like
1 1 SCOP 160981 Cas DxTHG

The following families have one or more weak hits: