Family Assignments

Domains Proteins SCOP Link Families
11 11 SCOP 52686 ABC transporter ATPase domain-like
9 9 SCOP 52375 Class I aminoacyl-tRNA synthetases (RS), catalytic domain
9 8 SCOP 81269 Extended AAA-ATPase domain
8 8 SCOP 52652 Nitrogenase iron protein-like
6 6 SCOP 51751 Tyrosine-dependent oxidoreductases
6 6 SCOP 52318 Class I glutamine amidotransferases (GAT)
6 6 SCOP 56802 Acetyl-CoA synthetase-like
6 5 SCOP 81268 Tandem AAA-ATPase domain
5 5 SCOP 51396 FMN-linked oxidoreductases
5 5 SCOP 52592 G proteins
5 5 SCOP 53417 GABA-aminotransferase-like
5 5 SCOP 55682 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
4 4 SCOP 48082 Methyl-coenzyme M reductase alpha and beta chain C-terminal domain
4 4 SCOP 51570 Class I aldolase
4 4 SCOP 51868 6-phosphogluconate dehydrogenase-like, N-terminal domain
4 4 SCOP 52403 N-type ATP pyrophosphatases
4 3 SCOP 52670 RecA protein-like (ATPase-domain)
4 4 SCOP 53816 Nitrogenase iron-molybdenum protein
4 4 SCOP 53851 Phosphate binding protein-like
4 4 SCOP 55094 Methyl-coenzyme M reductase alpha and beta chain N-terminal domain
3 3 SCOP 50282 Cold shock DNA-binding domain-like
3 3 SCOP 50448 Elongation factors
3 3 SCOP 51800 Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
3 3 SCOP 52441 BC N-terminal domain-like
3 2 SCOP 53068 Actin/HSP70
3 3 SCOP 53687 Tryptophan synthase beta subunit-like PLP-dependent enzymes
3 3 SCOP 53707 Formate dehydrogenase/DMSO reductase, domains 1-3
3 3 SCOP 53791 Tetrapyrrole methylase
3 2 SCOP 55113 Formylmethanofuran:tetrahydromethanopterin formyltransferase
3 3 SCOP 55327 PurM N-terminal domain-like
3 3 SCOP 56043 PurM C-terminal domain-like
3 2 SCOP 56067 BC ATP-binding domain-like
3 3 SCOP 56291 ROO N-terminal domain-like
3 3 SCOP 64490 RNA-polymerase beta-prime
3 3 SCOP 81656 Meta-cation ATPase, catalytic domain P
3 3 SCOP 88724 Pyruvate oxidase and decarboxylase Pyr module
2 2 SCOP 46580 Prefoldin
2 2 SCOP 47241 Ferritin
2 2 SCOP 47324 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
2 1 SCOP 47965 Transcription factor IIB (TFIIB), core domain
2 2 SCOP 48558 L-aspartase/fumarase
2 2 SCOP 48596 Group II chaperonin (CCT, TRIC), ATPase domain
2 2 SCOP 50466 EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
2 2 SCOP 51367 Histidine biosynthesis enzymes
2 2 SCOP 51381 Tryptophan biosynthesis enzymes
2 2 SCOP 51830 Formate/glycerate dehydrogenases, NAD-domain
2 2 SCOP 51883 Aminoacid dehydrogenase-like, C-terminal domain
2 2 SCOP 52017 LeuD-like
2 2 SCOP 52034 Group II chaperonin (CCT, TRIC), apical domain
2 2 SCOP 52081 Ribosomal proteins L15p and L18e
2 2 SCOP 52211 Succinyl-CoA synthetase domains
2 1 SCOP 52256 N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
2 2 SCOP 52834 Thioltransferase
2 2 SCOP 53272 Phosphoribosyltransferases (PRTases)
2 2 SCOP 53384 AAT-like
2 2 SCOP 53402 Cystathionine synthase-like
2 2 SCOP 53660 Dimeric isocitrate & isopropylmalate dehydrogenases
2 2 SCOP 53672 Aspartate/ornithine carbamoyltransferase
2 2 SCOP 53733 Aconitase iron-sulfur domain
2 2 SCOP 54229 Ribonuclease PH domain 1-like
2 2 SCOP 54914 Prokaryotic signal transducing protein
2 2 SCOP 55089 Methyl-coenzyme M reductase gamma chain
2 2 SCOP 55348 GAPDH-like
2 2 SCOP 55368 Dihydrodipicolinate reductase-like
2 2 SCOP 55921 Creatinase/aminopeptidase
2 2 SCOP 56236 Class II glutamine amidotransferases
2 2 SCOP 56251 Proteasome subunits
2 2 SCOP 56673 DNA polymerase I
2 2 SCOP 56763 Nickel-iron hydrogenase, large subunit
2 2 SCOP 63883 MoeA N-terminal region -like
2 2 SCOP 63944 Potassium channel NAD-binding domain
2 2 SCOP 64485 RNA-polymerase beta
2 2 SCOP 69599 mono-SIS domain
2 2 SCOP 109756 PhoU-like
2 2 SCOP 111284 Putative modulator of DNA gyrase, PmbA/TldD
2 2 SCOP 111353 Ammonium transporter
2 2 SCOP 142721 PyrH-like
2 2 SCOP 143812 GatB/GatE catalytic domain-like
1 1 SCOP 46610 Fe,Mn superoxide dismutase (SOD), N-terminal domain
1 1 SCOP 46925 RNA polymerase subunit RPB10
1 1 SCOP 46951 Double-stranded DNA-binding domain
1 1 SCOP 47447 Signal peptide-binding domain
1 1 SCOP 47808 5' to 3' exonuclease, C-terminal subdomain
1 1 SCOP 47974 Ribosomal protein S7
1 1 SCOP 48141 Ribosomal protein L19 (L19e)
1 1 SCOP 48184 Acetohydroxy acid isomeroreductase (ketol-acid reductoisomerase, KARI)
1 1 SCOP 48577 Isoprenyl diphosphate synthases
1 1 SCOP 49368 Superoxide reductase-like
1 1 SCOP 50114 C-terminal domain of ribosomal protein L2
1 1 SCOP 50183 Sm motif of small nuclear ribonucleoproteins, SNRNP
1 1 SCOP 50194 Ribosomal protein L14
1 1 SCOP 50250 Anticodon-binding domain
1 1 SCOP 50325 Inorganic pyrophosphatase
1 1 SCOP 50461 Ribosomal protein L3
1 1 SCOP 50482 NADH:FMN oxidoreductase-like
1 1 SCOP 50495 Prokaryotic proteases
1 1 SCOP 50678 ValRS/IleRS/LeuRS editing domain
1 1 SCOP 50892 Cyclophilin (peptidylprolyl isomerase)
1 1 SCOP 51183 dTDP-sugar isomerase
1 1 SCOP 51247 BC C-terminal domain-like
1 1 SCOP 51284 dUTPase-like
1 1 SCOP 51352 Triosephosphate isomerase (TIM)
1 1 SCOP 51375 Decarboxylase
1 1 SCOP 51413 Inosine monophosphate dehydrogenase (IMPDH)
1 1 SCOP 51420 Alanine racemase-like, N-terminal domain
1 1 SCOP 51594 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase)
1 1 SCOP 51605 Enolase
1 1 SCOP 51687 F420 dependent oxidoreductases
1 1 SCOP 51691 NadC C-terminal domain-like
1 1 SCOP 51714 tRNA-guanine transglycosylase
1 1 SCOP 51900 CoA-binding domain
1 1 SCOP 51999 PFL-like
1 1 SCOP 52005 Class III anaerobic ribonucleotide reductase NRDD subunit
1 1 SCOP 52022 Carbamoyl phosphate synthetase, small subunit N-terminal domain
1 1 SCOP 52043 Ribosomal protein L32e
1 1 SCOP 52157 Initiation factor IF2/eIF5b, domain 3
1 1 SCOP 52162 Ribosomal protein L13
1 1 SCOP 52167 Ribosomal protein L4
1 1 SCOP 52207 Hypothetical protein MTH538
1 1 SCOP 52300 S-adenosylhomocystein hydrolase
1 1 SCOP 52314 Ribosomal protein S2
1 1 SCOP 52397 Adenylyltransferase
1 1 SCOP 52419 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
1 1 SCOP 52468 Deoxyhypusine synthase, DHS
1 1 SCOP 52475 Pyruvate oxidase and decarboxylase, middle domain
1 1 SCOP 52491 Tubulin, GTPase domain
1 1 SCOP 52508 Homo-oligomeric flavin-containing Cys decarboxylases, HFCD
1 1 SCOP 52541 Nucleotide and nucleoside kinases
1 1 SCOP 52769 Arginase-like amidino hydrolases
1 1 SCOP 52773 Histone deacetylase, HDAC
1 1 SCOP 52901 Glutathione peroxidase-like
1 1 SCOP 52955 Anticodon-binding domain of Class II aaRS
1 1 SCOP 52973 ITPase (Ham1)
1 1 SCOP 53033 tRNA-intron endonuclease catalytic domain-like
1 1 SCOP 53045 5' to 3' exonuclease catalytic domain
1 1 SCOP 53057 beta-carbonic anhydrase, cab
1 1 SCOP 53099 Ribonuclease H
1 1 SCOP 53118 DnaQ-like 3'-5' exonuclease
1 1 SCOP 53138 Ribosomal protein L18 and S11
1 1 SCOP 53147 MTH1175-like
1 1 SCOP 53168 Purine and uridine phosphorylases
1 1 SCOP 53204 Bacterial dinuclear zinc exopeptidases
1 1 SCOP 53342 Fibrillarin homologue
1 1 SCOP 53354 Protein-L-isoaspartyl O-methyltransferase
1 1 SCOP 53464 glucose-1-phosphate thymidylyltransferase
1 1 SCOP 53620 Thiamin biosynthesis kinases
1 1 SCOP 53640 AraD-like aldolase/epimerase
1 1 SCOP 53698 double-SIS domain
1 1 SCOP 53721 ALDH-like
1 1 SCOP 53749 Phosphoglycerate kinase
1 1 SCOP 53763 UDP-N-acetylglucosamine 2-epimerase
1 1 SCOP 53775 Glutaminase/Asparaginase
1 1 SCOP 53811 TroA-like
1 1 SCOP 54193 L15e
1 1 SCOP 54212 Translational machinery components
1 1 SCOP 54224 DNA gyrase/MutL, second domain
1 1 SCOP 54289 ThiS
1 1 SCOP 54535 FKBP immunophilin/proline isomerase
1 1 SCOP 54632 CBS-domain pair
1 1 SCOP 54720 Fe,Mn superoxide dismutase (SOD), C-terminal domain
1 1 SCOP 54827 Enolase N-terminal domain-like
1 1 SCOP 54844 Ribosomal protein L22
1 1 SCOP 54894 Aspartate carbamoyltransferase, Regulatory-chain, N-terminal domain
1 1 SCOP 54920 Nucleoside diphosphate kinase, NDK
1 1 SCOP 54985 eEF-1beta-like
1 1 SCOP 55036 NAD-binding domain of HMG-CoA reductase
1 1 SCOP 55041 Molybdenum cofactor biosynthesis protein C, MoaC
1 1 SCOP 55069 Peptide methionine sulfoxide reductase
1 1 SCOP 55121 Pseudouridine synthase I TruA
1 1 SCOP 55130 Ribosomal protein L30p/L7e
1 1 SCOP 55206 RNA 3'-terminal phosphate cyclase, RPTC
1 1 SCOP 55209 Enolpyruvate transferase, EPT
1 1 SCOP 55262 GAD domain
1 1 SCOP 55283 Ribosomal protein L5
1 1 SCOP 55288 RPB5
1 1 SCOP 55308 Tubulin, C-terminal domain
1 1 SCOP 55316 L30e/L7ae ribosomal proteins
1 1 SCOP 55482 N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1
1 1 SCOP 55707 Biotin holoenzyme synthetase
1 1 SCOP 55822 YrdC-like
1 1 SCOP 55910 Ribosome anti-association factor eIF6 (aIF6)
1 1 SCOP 55932 Glutamine synthetase catalytic domain
1 1 SCOP 55946 TATA-box binding protein (TBP), C-terminal domain
1 1 SCOP 56048 Ribosomal protein S8
1 1 SCOP 56054 Ribosomal protein L6
1 1 SCOP 56081 Succinyl-CoA synthetase, beta-chain, N-terminal domain
1 1 SCOP 56105 SAICAR synthase
1 1 SCOP 56200 Methenyltetrahydromethanopterin cyclohydrolase
1 1 SCOP 56220 DNase I-like
1 1 SCOP 56318 Nitrilase
1 1 SCOP 56323 ADC synthase
1 1 SCOP 56328 Lactate & malate dehydrogenases, C-terminal domain
1 1 SCOP 56350 Lambda integrase-like, catalytic core
1 1 SCOP 56426 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain
1 1 SCOP 56530 FAH
1 1 SCOP 56543 Substrate-binding domain of HMG-CoA reductase
1 1 SCOP 56656 Inositol monophosphatase/fructose-1,6-bisphosphatase-like
1 1 SCOP 56713 Prokaryotic type I DNA topoisomerase
1 1 SCOP 56727 DNA topoisomerase IV, alpha subunit
1 1 SCOP 56748 PriA-like
1 1 SCOP 56753 D-aminoacid aminotransferase-like PLP-dependent enzymes
1 1 SCOP 56809 Ribosomal protein L1
1 1 SCOP 56822 Hybrid cluster protein (prismane protein)
1 1 SCOP 56895 Aquaporin-like
1 1 SCOP 57822 Hypothetical protein MTH1184
1 1 SCOP 63966 Precorrin-8X methylmutase CbiC/CobH
1 1 SCOP 64006 Undecaprenyl diphosphate synthase
1 1 SCOP 64077 MTH938-like
1 1 SCOP 64089 BadF/BadG/BcrA/BcrD-like
1 1 SCOP 64117 tRNA(1-methyladenosine) methyltransferase-like
1 1 SCOP 64154 YjeF N-terminal domain-like
1 1 SCOP 64168 SurE-like
1 1 SCOP 64372 3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB
1 1 SCOP 64427 DNA double-strand break repair nuclease
1 1 SCOP 64511 Phosphoserine phosphatase
1 1 SCOP 64587 C-terminal domain of ProRS
1 1 SCOP 69026 Hypothetical protein MTH865
1 1 SCOP 69427 UDP-galactopyranose mutase, N-terminal domain
1 1 SCOP 69602 L-histidinol dehydrogenase HisD
1 1 SCOP 69746 Pseudouridine synthase II TruB
1 1 SCOP 69787 YggU-like
1 1 SCOP 69820 MTH1598-like
1 1 SCOP 69865 Argininosuccinate synthetase, C-terminal domain
1 1 SCOP 69892 Iron-containing alcohol dehydrogenase
1 1 SCOP 74759 C-terminal domain of class I lysyl-tRNA synthetase
1 1 SCOP 74762 Conserved hypothetical protein MTH1747
1 1 SCOP 74955 Hypothetical protein MTH1 (MT0001), insert domain
1 1 SCOP 75041 SelR domain
1 1 SCOP 75073 Hydantoinase (dihydropyrimidinase), catalytic domain
1 1 SCOP 75170 DsrEF-like
1 1 SCOP 75176 D-ribose-5-phosphate isomerase (RpiA), catalytic domain
1 1 SCOP 75182 Hypothetical protein MTH777 (MT0777)
1 1 SCOP 75221 Hypothetical protein MTH1 (MT0001), dimerisation domain
1 1 SCOP 75292 YjeF C-terminal domain-like
1 1 SCOP 75297 N-acetyl-l-glutamate kinase
1 1 SCOP 75305 Amidase signature (AS) enzymes
1 1 SCOP 75413 Hypothetical protein MTH1880
1 1 SCOP 75434 Divalent ion tolerance proteins CutA (CutA1)
1 1 SCOP 75570 Archaeal IMP cyclohydrolase PurO
1 1 SCOP 81323 Voltage-gated potassium channels
1 1 SCOP 81664 Calcium ATPase, transmembrane domain M
1 1 SCOP 82258 SAH/MTA deaminase-like
1 1 SCOP 82267 TatD Mg-dependent DNase-like
1 1 SCOP 82336 Shikimate dehydrogenase-like
1 1 SCOP 82388 Predicted hydrolases Cof
1 1 SCOP 82472 Precorrin-6Y methyltransferase (CbiT)
1 1 SCOP 82540 Trehalose-6-phosphate synthase, OtsA
1 1 SCOP 82698 PurS subunit of FGAM synthetase
1 1 SCOP 82852 Acetyl-CoA synthase
1 1 SCOP 88683 Eukaryotic ODC-like
1 1 SCOP 88749 Pyruvate oxidase and decarboxylase PP module
1 1 SCOP 88784 rRNA adenine dimethylase-like
1 1 SCOP 89125 Nop domain
1 1 SCOP 89332 DNA replication initiator (cdc21/cdc54) N-terminal domain
1 1 SCOP 89494 HMGL-like
1 1 SCOP 89716 XPF/Rad1/Mus81 nuclease
1 1 SCOP 89734 L-sulfolactate dehydrogenase-like
1 1 SCOP 89916 DNA-binding protein Tfx
1 1 SCOP 89958 MTH1187-like
1 1 SCOP 90046 Arginine decarboxylase
1 1 SCOP 100921 Heat shock protein 70kD (HSP70), peptide-binding domain
1 1 SCOP 100967 Translation initiation factor 2 beta, aIF2beta, N-terminal domain
1 1 SCOP 101333 Hypothetical protein MTH393
1 1 SCOP 101340 HD domain
1 1 SCOP 101354 Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
1 1 SCOP 101410 PBS lyase HEAT-like repeat
1 1 SCOP 101468 CMD-like
1 1 SCOP 101745 RNase P subunit p29-like
1 1 SCOP 101773 MTH1895
1 1 SCOP 101995 PA3696/SPS0176-like
1 1 SCOP 102111 (2r)-phospho-3-sulfolactate synthase ComA
1 1 SCOP 102325 F420-dependent methylenetetrahydromethanopterin dehydrogenase (MTD)
1 1 SCOP 102463 Peptidyl-tRNA hydrolase II
1 1 SCOP 102646 CoaB-like
1 1 SCOP 102769 ATP-dependent protease Lon (La), catalytic domain
1 1 SCOP 103166 Ta1353-like
1 1 SCOP 103264 Chorismate synthase, AroC
1 1 SCOP 103366 Hypothetical protein PH1602
1 1 SCOP 103487 V-type ATP synthase subunit C
1 1 SCOP 103492 Preprotein translocase SecY subunit
1 1 SCOP 109725 Conserved carboxylase domain
1 1 SCOP 110436 Ornithine cyclodeaminase-like
1 1 SCOP 110513 IF2B-like
1 1 SCOP 110616 MTH1675-like
1 1 SCOP 110784 Hypothetical protein MTH677
1 1 SCOP 111039 YjbQ-like
1 1 SCOP 111219 ArgJ-like
1 1 SCOP 111233 YfcE-like
1 1 SCOP 111250 Sulfolobus fructose-1,6-bisphosphatase-like
1 1 SCOP 111322 AF1104-like
1 1 SCOP 111332 NAD kinase-like
1 1 SCOP 116727 TrkA C-terminal domain-like
1 1 SCOP 116821 Rps17e-like
1 1 SCOP 117458 FumA C-terminal domain-like
1 1 SCOP 117783 YbjQ-like
1 1 SCOP 117795 Formaldehyde-activating enzyme, FAE
1 1 SCOP 140777 HMD dimerization domain-like
1 1 SCOP 141301 GatD N-terminal domain-like
1 1 SCOP 141368 UbiD middle domain-like
1 1 SCOP 141735 HisI-like
1 1 SCOP 141755 PdxS-like
1 1 SCOP 141942 Thi4-like
1 1 SCOP 141979 AF0055-like
1 1 SCOP 142020 Nqo1 FMN-binding domain-like
1 1 SCOP 142040 AF1403 C-terminal domain-like
1 1 SCOP 142339 CofD-like
1 1 SCOP 142420 Brix domain
1 1 SCOP 142622 Met-10+ protein-like
1 1 SCOP 142683 SelA-like
1 1 SCOP 142701 RibD C-terminal domain-like
1 1 SCOP 142755 NadA-like
1 1 SCOP 142824 ComB-like
1 1 SCOP 143448 AMMECR1-like
1 1 SCOP 143916 RNase Z-like
1 1 SCOP 143927 beta-CASP RNA-metabolising hydrolases
1 1 SCOP 143976 lvD/EDD N-terminal domain-like
1 1 SCOP 143979 Type I restriction modification DNA specificity domain
1 1 SCOP 144011 CofE-like
1 1 SCOP 144028 Nqo4-like
1 1 SCOP 158338 Rps19E-like
1 1 SCOP 158373 AF1782-like
1 1 SCOP 159049 MTH1368 C-terminal domain-like
1 1 SCOP 159164 MTH863-like
1 1 SCOP 159408 Zn-dependent arginine carboxypeptidase-like
1 1 SCOP 159464 AF0587 domain-like
1 1 SCOP 159523 AF0751-like
1 1 SCOP 159526 PurP N-terminal domain-like
1 1 SCOP 159697 TRM1-like
1 1 SCOP 159704 SepSecS-like
1 1 SCOP 159768 Phosphomethylpyrimidine kinase C-terminal domain-like
1 1 SCOP 160364 MTH889-like
1 1 SCOP 160375 RplX-like
1 1 SCOP 160415 AF1396-like
1 1 SCOP 160611 PH0223-like
1 1 SCOP 160804 PurP ATP-binding domain-like
1 1 SCOP 160976 AF1531-like

The following families have one or more weak hits: