Family Assignments

Domains Proteins SCOP Link Families
50 50 SCOP 52686 ABC transporter ATPase domain-like
12 12 SCOP 52592 G proteins
12 9 SCOP 81269 Extended AAA-ATPase domain
11 11 SCOP 55682 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
10 6 SCOP 81268 Tandem AAA-ATPase domain
9 9 SCOP 51446 Amylase, catalytic domain
8 8 SCOP 51751 Tyrosine-dependent oxidoreductases
8 8 SCOP 52375 Class I aminoacyl-tRNA synthetases (RS), catalytic domain
8 4 SCOP 53068 Actin/HSP70
8 8 SCOP 53851 Phosphate binding protein-like
5 5 SCOP 51570 Class I aldolase
5 5 SCOP 51609 D-glucarate dehydratase-like
5 5 SCOP 52652 Nitrogenase iron protein-like
5 5 SCOP 52670 RecA protein-like (ATPase-domain)
5 5 SCOP 53402 Cystathionine synthase-like
5 5 SCOP 53614 Ribokinase-like
5 5 SCOP 54827 Enolase N-terminal domain-like
5 5 SCOP 161099 MetI-like
4 4 SCOP 51396 FMN-linked oxidoreductases
4 4 SCOP 53204 Bacterial dinuclear zinc exopeptidases
4 4 SCOP 53272 Phosphoribosyltransferases (PRTases)
4 2 SCOP 53902 Thiolase-related
3 3 SCOP 47918 C-terminal domain of alpha and beta subunits of F1 ATP synthase
3 3 SCOP 49803 beta-Galactosidase/glucuronidase, N-terminal domain
3 3 SCOP 51487 beta-glycanases
3 3 SCOP 51868 6-phosphogluconate dehydrogenase-like, N-terminal domain
3 3 SCOP 52173 CheY-related
3 3 SCOP 52318 Class I glutamine amidotransferases (GAT)
3 3 SCOP 52403 N-type ATP pyrophosphatases
3 3 SCOP 52541 Nucleotide and nucleoside kinases
3 3 SCOP 53168 Purine and uridine phosphorylases
3 3 SCOP 53384 AAT-like
3 3 SCOP 53672 Aspartate/ornithine carbamoyltransferase
3 3 SCOP 53687 Tryptophan synthase beta subunit-like PLP-dependent enzymes
3 3 SCOP 53823 L-arabinose binding protein-like
3 3 SCOP 54212 Translational machinery components
3 3 SCOP 55879 DNA gyrase/MutL, N-terminal domain
3 1 SCOP 55974 S-adenosylmethionine synthetase
3 2 SCOP 56067 BC ATP-binding domain-like
3 3 SCOP 56236 Class II glutamine amidotransferases
3 3 SCOP 56713 Prokaryotic type I DNA topoisomerase
3 3 SCOP 56802 Acetyl-CoA synthetase-like
3 3 SCOP 75459 Pseudouridine synthase RsuA/RluD
3 3 SCOP 82075 Kid/PemK
3 3 SCOP 82550 DegV-like
3 3 SCOP 89572 Biotin dependent carboxylase carboxyltransferase domain
3 3 SCOP 142721 PyrH-like
2 2 SCOP 47241 Ferritin
2 2 SCOP 48191 UDP-glucose/GDP-mannose dehydrogenase dimerisation domain
2 2 SCOP 48558 L-aspartase/fumarase
2 2 SCOP 50282 Cold shock DNA-binding domain-like
2 2 SCOP 50448 Elongation factors
2 2 SCOP 51262 Glucose permease-like
2 2 SCOP 51591 Class II FBP aldolase
2 2 SCOP 51599 Class I DAHP synthetase
2 2 SCOP 51883 Aminoacid dehydrogenase-like, C-terminal domain
2 1 SCOP 52441 BC N-terminal domain-like
2 2 SCOP 52789 Low-molecular-weight phosphotyrosine protein phosphatases
2 1 SCOP 53080 Acetokinase-like
2 1 SCOP 53089 Glycerol kinase
2 2 SCOP 53099 Ribonuclease H
2 2 SCOP 53138 Ribosomal protein L18 and S11
2 2 SCOP 53417 GABA-aminotransferase-like
2 2 SCOP 53464 glucose-1-phosphate thymidylyltransferase
2 2 SCOP 53620 Thiamin biosynthesis kinases
2 2 SCOP 53785 Phosphofructokinase
2 1 SCOP 54229 Ribonuclease PH domain 1-like
2 1 SCOP 54981 EF-G/eEF-2 domains III and V
2 2 SCOP 55209 Enolpyruvate transferase, EPT
2 2 SCOP 55299 YjgF/L-PSP
2 2 SCOP 55327 PurM N-terminal domain-like
2 1 SCOP 56054 Ribosomal protein L6
2 2 SCOP 56720 Type II DNA topoisomerase
2 2 SCOP 69892 Iron-containing alcohol dehydrogenase
2 1 SCOP 74656 CoA transferase alpha subunit-like
2 2 SCOP 75218 SpoU-like RNA 2'-O ribose methyltransferase
2 2 SCOP 75621 Release factor
2 2 SCOP 75648 ABC transporter involved in vitamin B12 uptake, BtuC
2 2 SCOP 81605 PP2C-like
2 2 SCOP 88724 Pyruvate oxidase and decarboxylase Pyr module
2 2 SCOP 88749 Pyruvate oxidase and decarboxylase PP module
2 2 SCOP 88947 Sigma2 domain of RNA polymerase sigma factors
2 2 SCOP 89494 HMGL-like
2 2 SCOP 89797 CoA-transferase family III (CaiB/BaiF)
2 2 SCOP 89800 Deoxycytidylate deaminase-like
2 2 SCOP 100921 Heat shock protein 70kD (HSP70), peptide-binding domain
2 2 SCOP 101340 HD domain
2 2 SCOP 102928 NifU/IscU domain
2 2 SCOP 118216 Proton glutamate symport protein
2 2 SCOP 142635 hypothetical RNA methyltransferase
2 1 SCOP 143860 Polyphosphate kinase C-terminal domain
2 2 SCOP 143976 lvD/EDD N-terminal domain-like
2 2 SCOP 161071 SNF-like
1 1 SCOP 46566 Chaperone J-domain
1 1 SCOP 46903 Spo0A
1 1 SCOP 46907 Ribosomal protein L11, C-terminal domain
1 1 SCOP 46947 Ribosomal protein S13
1 1 SCOP 47064 Ribosomal protein S15
1 1 SCOP 47204 Medium chain acyl-CoA dehydrogenase-like, C-terminal domain
1 1 SCOP 47324 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
1 1 SCOP 47447 Signal peptide-binding domain
1 1 SCOP 47790 C-terminal domain of RNA polymerase alpha subunit
1 1 SCOP 47974 Ribosomal protein S7
1 1 SCOP 48184 Acetohydroxy acid isomeroreductase (ketol-acid reductoisomerase, KARI)
1 1 SCOP 48577 Isoprenyl diphosphate synthases
1 1 SCOP 48593 GroEL chaperone, ATPase domain
1 1 SCOP 50114 C-terminal domain of ribosomal protein L2
1 1 SCOP 50136 Alcohol dehydrogenase-like, N-terminal domain
1 1 SCOP 50194 Ribosomal protein L14
1 1 SCOP 50250 Anticodon-binding domain
1 1 SCOP 50461 Ribosomal protein L3
1 1 SCOP 50466 EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
1 1 SCOP 50495 Prokaryotic proteases
1 1 SCOP 50678 ValRS/IleRS/LeuRS editing domain
1 1 SCOP 50719 Gln-tRNA synthetase (GlnRS), C-terminal (anticodon-binding) domain
1 1 SCOP 50892 Cyclophilin (peptidylprolyl isomerase)
1 1 SCOP 51147 Pectin methylesterase
1 1 SCOP 51171 GlmU C-terminal domain-like
1 1 SCOP 51183 dTDP-sugar isomerase
1 1 SCOP 51284 dUTPase-like
1 1 SCOP 51352 Triosephosphate isomerase (TIM)
1 1 SCOP 51372 D-ribulose-5-phosphate 3-epimerase
1 1 SCOP 51392 Thiamin phosphate synthase
1 1 SCOP 51413 Inosine monophosphate dehydrogenase (IMPDH)
1 1 SCOP 51420 Alanine racemase-like, N-terminal domain
1 1 SCOP 51431 Aldo-keto reductases (NADP)
1 1 SCOP 51521 Family 1 of glycosyl hydrolase
1 1 SCOP 51605 Enolase
1 1 SCOP 51622 Pyruvate kinase
1 1 SCOP 51629 Pyruvate phosphate dikinase, C-terminal domain
1 1 SCOP 51691 NadC C-terminal domain-like
1 1 SCOP 51714 tRNA-guanine transglycosylase
1 1 SCOP 51800 Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
1 1 SCOP 51934 Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain
1 1 SCOP 51999 PFL-like
1 1 SCOP 52005 Class III anaerobic ribonucleotide reductase NRDD subunit
1 1 SCOP 52010 Pyruvate phosphate dikinase, central domain
1 1 SCOP 52017 LeuD-like
1 1 SCOP 52022 Carbamoyl phosphate synthetase, small subunit N-terminal domain
1 1 SCOP 52030 GroEL-like chaperone, apical domain
1 1 SCOP 52081 Ribosomal proteins L15p and L18e
1 1 SCOP 52097 Clp protease, ClpP subunit
1 1 SCOP 52103 Crotonase-like
1 1 SCOP 52122 Lumazine synthase
1 1 SCOP 52147 Mug-like
1 1 SCOP 52152 FabD-like
1 1 SCOP 52162 Ribosomal protein L13
1 1 SCOP 52167 Ribosomal protein L4
1 1 SCOP 52256 N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
1 1 SCOP 52305 Type II 3-dehydroquinate dehydratase
1 1 SCOP 52314 Ribosomal protein S2
1 1 SCOP 52339 Methylglyoxal synthase, MgsA
1 1 SCOP 52397 Adenylyltransferase
1 1 SCOP 52414 UDP-glucose/GDP-mannose dehydrogenase C-terminal domain
1 1 SCOP 52419 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
1 1 SCOP 52432 ETFP subunits
1 1 SCOP 52471 C-terminal domain of the electron transfer flavoprotein alpha subunit
1 1 SCOP 52491 Tubulin, GTPase domain
1 1 SCOP 52513 NagB-like
1 1 SCOP 52584 Phosphoribulokinase/pantothenate kinase
1 1 SCOP 52729 PTS IIb component
1 1 SCOP 52734 Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT)
1 1 SCOP 52769 Arginase-like amidino hydrolases
1 1 SCOP 52901 Glutathione peroxidase-like
1 1 SCOP 52931 Pyruvate-ferredoxin oxidoreductase, PFOR, domain II
1 1 SCOP 52944 ATP synthase (F1-ATPase), gamma subunit
1 1 SCOP 52955 Anticodon-binding domain of Class II aaRS
1 1 SCOP 52973 ITPase (Ham1)
1 1 SCOP 52976 Maf-like
1 1 SCOP 53045 5' to 3' exonuclease catalytic domain
1 1 SCOP 53179 Peptidyl-tRNA hydrolase-like
1 1 SCOP 53219 MogA-like
1 1 SCOP 53224 Aminoacid dehydrogenases
1 1 SCOP 53240 Malic enzyme N-domain
1 1 SCOP 53324 Pyruvate-ferredoxin oxidoreductase, PFOR, domain III
1 1 SCOP 53329 Formyltransferase
1 1 SCOP 53624 MurCDEF
1 1 SCOP 53629 Folylpolyglutamate synthetase
1 1 SCOP 53660 Dimeric isocitrate & isopropylmalate dehydrogenases
1 1 SCOP 53682 Aspartate/glutamate racemase
1 1 SCOP 53698 double-SIS domain
1 1 SCOP 53701 Phosphoglucose isomerase, PGI
1 1 SCOP 53721 ALDH-like
1 1 SCOP 53733 Aconitase iron-sulfur domain
1 1 SCOP 53749 Phosphoglycerate kinase
1 1 SCOP 53760 Peptidoglycan biosynthesis glycosyltransferase MurG
1 1 SCOP 53763 UDP-N-acetylglucosamine 2-epimerase
1 1 SCOP 53766 Oligosaccharide phosphorylase
1 1 SCOP 53775 Glutaminase/Asparaginase
1 1 SCOP 53791 Tetrapyrrole methylase
1 1 SCOP 53796 PEP carboxykinase C-terminal domain
1 1 SCOP 53804 Cobalt chelatase CbiK
1 1 SCOP 53914 Chalcone synthase-like
1 1 SCOP 53921 Fe-only hydrogenase
1 1 SCOP 54198 HIT (HINT, histidine triad) family of protein kinase-interacting proteins
1 1 SCOP 54224 DNA gyrase/MutL, second domain
1 1 SCOP 54535 FKBP immunophilin/proline isomerase
1 1 SCOP 54571 Ribosomal protein S19
1 1 SCOP 54748 Ribosomal L11/L12e N-terminal domain
1 1 SCOP 54815 Prokaryotic type KH domain (KH-domain type II)
1 1 SCOP 54822 Ribosomal protein S3 C-terminal domain
1 1 SCOP 55000 Ribosomal protein S10
1 1 SCOP 55032 Bacterial exopeptidase dimerisation domain
1 1 SCOP 55041 Molybdenum cofactor biosynthesis protein C, MoaC
1 1 SCOP 55069 Peptide methionine sulfoxide reductase
1 1 SCOP 55121 Pseudouridine synthase I TruA
1 1 SCOP 55178 Ribosomal protein S4
1 1 SCOP 55187 Threonyl-tRNA synthetase (ThrRS), second 'additional' domain
1 1 SCOP 55195 Ribosome recycling factor, RRF
1 1 SCOP 55283 Ribosomal protein L5
1 1 SCOP 55308 Tubulin, C-terminal domain
1 1 SCOP 55348 GAPDH-like
1 1 SCOP 55368 Dihydrodipicolinate reductase-like
1 1 SCOP 55505 Neurolysin-like
1 1 SCOP 55875 Heat shock protein 90, HSP90, N-terminal domain
1 1 SCOP 55932 Glutamine synthetase catalytic domain
1 1 SCOP 56004 Molybdenum cofactor-binding domain
1 1 SCOP 56038 B3/B4 domain of PheRS, PheT
1 1 SCOP 56043 PurM C-terminal domain-like
1 1 SCOP 56048 Ribosomal protein S8
1 1 SCOP 56060 ATP-binding domain of peptide synthetases
1 1 SCOP 56085 Pyruvate phosphate dikinase, N-terminal domain
1 1 SCOP 56105 SAICAR synthase
1 1 SCOP 56184 Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase (MurB), N-terminal domain
1 1 SCOP 56195 Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain
1 1 SCOP 56220 DNase I-like
1 1 SCOP 56229 Aldehyde ferredoxin oxidoreductase, N-terminal domain
1 1 SCOP 56267 DmpA-like
1 1 SCOP 56421 Peptide deformylase
1 1 SCOP 56426 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain
1 1 SCOP 56530 FAH
1 1 SCOP 56554 Insert subdomain of RNA polymerase alpha subunit
1 1 SCOP 56602 beta-Lactamase/D-ala carboxypeptidase
1 1 SCOP 56646 Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains
1 1 SCOP 56673 DNA polymerase I
1 1 SCOP 56732 DNA primase DnaG catalytic core
1 1 SCOP 56753 D-aminoacid aminotransferase-like PLP-dependent enzymes
1 1 SCOP 56797 Dehydroquinate synthase, DHQS
1 1 SCOP 56809 Ribosomal protein L1
1 1 SCOP 56822 Hybrid cluster protein (prismane protein)
1 1 SCOP 57792 DNA primase zinc finger
1 1 SCOP 63412 MPP-like
1 1 SCOP 63883 MoeA N-terminal region -like
1 1 SCOP 63984 Sir2 family of transcriptional regulators
1 1 SCOP 64006 Undecaprenyl diphosphate synthase
1 1 SCOP 64095 Germination protease
1 1 SCOP 64159 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain
1 1 SCOP 64162 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, catalytic domain
1 1 SCOP 64183 Manganese-dependent inorganic pyrophosphatase (family II)
1 1 SCOP 64186 HPr kinase HprK C-terminal domain
1 1 SCOP 64198 AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC
1 1 SCOP 64264 Prokaryotic ribosomal protein L17
1 1 SCOP 64372 3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB
1 1 SCOP 64398 Hsp33 domain
1 1 SCOP 64485 RNA-polymerase beta
1 1 SCOP 64490 RNA-polymerase beta-prime
1 1 SCOP 68924 PEP carboxykinase N-terminal domain
1 1 SCOP 69066 RNase III catalytic domain-like
1 1 SCOP 69337 Alpha subunit of glutamate synthase, C-terminal domain
1 1 SCOP 69427 UDP-galactopyranose mutase, N-terminal domain
1 1 SCOP 69501 DTD-like
1 1 SCOP 69557 Spermidine synthase
1 1 SCOP 69599 mono-SIS domain
1 1 SCOP 69670 UDP-galactopyranose mutase
1 1 SCOP 69746 Pseudouridine synthase II TruB
1 1 SCOP 69865 Argininosuccinate synthetase, C-terminal domain
1 1 SCOP 74732 Ribosomal protein L20
1 1 SCOP 74911 Aldose 1-epimerase (mutarotase)
1 1 SCOP 74983 Small protein B (SmpB)
1 1 SCOP 75041 SelR domain
1 1 SCOP 75073 Hydantoinase (dihydropyrimidinase), catalytic domain
1 1 SCOP 75079 Renal dipeptidase
1 1 SCOP 75082 Uronate isomerase-like
1 1 SCOP 75090 IolI-like
1 1 SCOP 75264 Glucose-inhibited division protein B (GidB)
1 1 SCOP 75292 YjeF C-terminal domain-like
1 1 SCOP 75297 N-acetyl-l-glutamate kinase
1 1 SCOP 75323 Exonuclease RecJ
1 1 SCOP 75554 Smc hinge domain
1 1 SCOP 75626 YebC-like
1 1 SCOP 81768 Pre-protein crosslinking domain of SecA
1 1 SCOP 81800 Putative methyltransferase TM0872, insert domain
1 1 SCOP 81887 Helical scaffold and wing domains of SecA
1 1 SCOP 82052 Obg GTP-binding protein N-terminal domain
1 1 SCOP 82261 N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain
1 1 SCOP 82267 TatD Mg-dependent DNase-like
1 1 SCOP 82283 Homocysteine S-methyltransferase
1 1 SCOP 82371 YbeA-like
1 1 SCOP 82545 GckA/TtuD-like
1 1 SCOP 82661 Poly A polymerase head domain-like
1 1 SCOP 88746 PFOR Pyr module
1 1 SCOP 88760 TK-like PP module
1 1 SCOP 88771 PFOR PP module
1 1 SCOP 88854 Protein kinases, catalytic subunit
1 1 SCOP 89108 Hypothetical protein YteR
1 1 SCOP 89624 Ribose/Galactose isomerase RpiB/AlsB
1 1 SCOP 89629 tRNA(m1G37)-methyltransferase TrmD
1 1 SCOP 89724 Macro domain
1 1 SCOP 90124 ABC transporter transmembrane region
1 1 SCOP 101354 Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
1 1 SCOP 101822 Aminopeptidase/glucanase lid domain
1 1 SCOP 101884 Glycosyl hydrolases family 32 N-terminal domain
1 1 SCOP 101905 GyrA/ParC C-terminal domain-like
1 1 SCOP 101951 Pectate transeliminase
1 1 SCOP 102406 MoCo carrier protein-like
1 1 SCOP 102557 rRNA methyltransferase RlmA
1 1 SCOP 102646 CoaB-like
1 1 SCOP 102663 Phosphotransacetylase
1 1 SCOP 102706 NIF3 (NGG1p interacting factor 3)-like
1 1 SCOP 102755 Hsp90 middle domain
1 1 SCOP 102769 ATP-dependent protease Lon (La), catalytic domain
1 1 SCOP 102945 RelA/SpoT domain
1 1 SCOP 103264 Chorismate synthase, AroC
1 1 SCOP 109725 Conserved carboxylase domain
1 1 SCOP 109756 PhoU-like
1 1 SCOP 109953 Glycosyl Hydrolase Family 88
1 1 SCOP 110318 KduI-like
1 1 SCOP 110377 UxuA-like
1 1 SCOP 110388 MoCo biosynthesis proteins
1 1 SCOP 110520 Methenyltetrahydrofolate synthetase
1 1 SCOP 110711 Hypothetical protein TT1679
1 1 SCOP 110734 Glycosyl transferases group 1
1 1 SCOP 111219 ArgJ-like
1 1 SCOP 111305 Recombination protein RecR
1 1 SCOP 111332 NAD kinase-like
1 1 SCOP 111338 QueA-like
1 1 SCOP 117362 NanE-like
1 1 SCOP 117458 FumA C-terminal domain-like
1 1 SCOP 117888 Ribosomal protein L16p
1 1 SCOP 117997 TrmE formyl-THF-binding domain
1 1 SCOP 118197 YaeB-like
1 1 SCOP 140991 FtsH protease domain-like
1 1 SCOP 141092 Ribosomal protein L21p
1 1 SCOP 141245 Ribosomal protein L19
1 1 SCOP 141735 HisI-like
1 1 SCOP 141837 GatZ-like
1 1 SCOP 142077 HTS-like
1 1 SCOP 142093 ThiI-like
1 1 SCOP 142434 CinA-like
1 1 SCOP 142606 N-6 DNA Methylase-like
1 1 SCOP 142696 RibA-like
1 1 SCOP 142701 RibD C-terminal domain-like
1 1 SCOP 142735 DeoB catalytic domain-like
1 1 SCOP 143598 YojJ-like
1 1 SCOP 143632 ApbE-like
1 1 SCOP 143857 DeoB insert domain-like
1 1 SCOP 143916 RNase Z-like
1 1 SCOP 143927 beta-CASP RNA-metabolising hydrolases
1 1 SCOP 143979 Type I restriction modification DNA specificity domain
1 1 SCOP 158600 MgsA/YrvN C-terminal domain-like
1 1 SCOP 159112 RNB domain-like
1 1 SCOP 159444 SP0239-like
1 1 SCOP 161094 MgtE membrane domain-like

The following families have one or more weak hits: