Family Assignments

Domains Proteins SCOP Link Families
12 10 SCOP 81269 Extended AAA-ATPase domain
11 11 SCOP 52686 ABC transporter ATPase domain-like
9 9 SCOP 51751 Tyrosine-dependent oxidoreductases
9 9 SCOP 52670 RecA protein-like (ATPase-domain)
8 8 SCOP 52375 Class I aminoacyl-tRNA synthetases (RS), catalytic domain
8 8 SCOP 55682 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
8 8 SCOP 56067 BC ATP-binding domain-like
8 5 SCOP 81268 Tandem AAA-ATPase domain
8 8 SCOP 117984 GGDEF domain
7 7 SCOP 52592 G proteins
7 7 SCOP 53417 GABA-aminotransferase-like
6 6 SCOP 52441 BC N-terminal domain-like
6 6 SCOP 53851 Phosphate binding protein-like
5 5 SCOP 52318 Class I glutamine amidotransferases (GAT)
5 5 SCOP 52652 Nitrogenase iron protein-like
5 5 SCOP 58105 Methyl-accepting chemotaxis protein (MCP) signaling domain
4 4 SCOP 51570 Class I aldolase
4 2 SCOP 53068 Actin/HSP70
4 4 SCOP 53687 Tryptophan synthase beta subunit-like PLP-dependent enzymes
4 4 SCOP 56043 PurM C-terminal domain-like
3 3 SCOP 48558 L-aspartase/fumarase
3 3 SCOP 50448 Elongation factors
3 3 SCOP 50678 ValRS/IleRS/LeuRS editing domain
3 3 SCOP 51247 BC C-terminal domain-like
3 3 SCOP 51381 Tryptophan biosynthesis enzymes
3 3 SCOP 51396 FMN-linked oxidoreductases
3 3 SCOP 51800 Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
3 3 SCOP 52211 Succinyl-CoA synthetase domains
3 3 SCOP 52403 N-type ATP pyrophosphatases
3 3 SCOP 53384 AAT-like
3 3 SCOP 55327 PurM N-terminal domain-like
3 3 SCOP 55348 GAPDH-like
3 3 SCOP 56236 Class II glutamine amidotransferases
3 3 SCOP 144028 Nqo4-like
2 2 SCOP 47918 C-terminal domain of alpha and beta subunits of F1 ATP synthase
2 2 SCOP 48577 Isoprenyl diphosphate synthases
2 2 SCOP 50282 Cold shock DNA-binding domain-like
2 2 SCOP 50466 EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
2 2 SCOP 50495 Prokaryotic proteases
2 2 SCOP 51183 dTDP-sugar isomerase
2 2 SCOP 51284 dUTPase-like
2 2 SCOP 51367 Histidine biosynthesis enzymes
2 2 SCOP 51392 Thiamin phosphate synthase
2 2 SCOP 51420 Alanine racemase-like, N-terminal domain
2 2 SCOP 51830 Formate/glycerate dehydrogenases, NAD-domain
2 2 SCOP 51868 6-phosphogluconate dehydrogenase-like, N-terminal domain
2 2 SCOP 51934 Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain
2 2 SCOP 52017 LeuD-like
2 2 SCOP 52508 Homo-oligomeric flavin-containing Cys decarboxylases, HFCD
2 2 SCOP 52541 Nucleotide and nucleoside kinases
2 2 SCOP 52773 Histone deacetylase, HDAC
2 2 SCOP 52901 Glutathione peroxidase-like
2 2 SCOP 53099 Ribonuclease H
2 2 SCOP 53272 Phosphoribosyltransferases (PRTases)
2 2 SCOP 53329 Formyltransferase
2 2 SCOP 53402 Cystathionine synthase-like
2 2 SCOP 53464 glucose-1-phosphate thymidylyltransferase
2 2 SCOP 53660 Dimeric isocitrate & isopropylmalate dehydrogenases
2 2 SCOP 53672 Aspartate/ornithine carbamoyltransferase
2 1 SCOP 53682 Aspartate/glutamate racemase
2 2 SCOP 53721 ALDH-like
2 2 SCOP 53733 Aconitase iron-sulfur domain
2 1 SCOP 53902 Thiolase-related
2 2 SCOP 54229 Ribonuclease PH domain 1-like
2 2 SCOP 54914 Prokaryotic signal transducing protein
2 1 SCOP 54981 EF-G/eEF-2 domains III and V
2 2 SCOP 55209 Enolpyruvate transferase, EPT
2 2 SCOP 55368 Dihydrodipicolinate reductase-like
2 2 SCOP 55667 Ribonuclease PH domain 2-like
2 2 SCOP 55921 Creatinase/aminopeptidase
2 1 SCOP 55974 S-adenosylmethionine synthetase
2 2 SCOP 56323 ADC synthase
2 2 SCOP 56421 Peptide deformylase
2 2 SCOP 56771 Nickel-iron hydrogenase, small subunit
2 2 SCOP 56802 Acetyl-CoA synthetase-like
2 2 SCOP 69912 Clc chloride channel
2 2 SCOP 75621 Release factor
2 2 SCOP 89494 HMGL-like
2 2 SCOP 89572 Biotin dependent carboxylase carboxyltransferase domain
2 2 SCOP 109725 Conserved carboxylase domain
2 1 SCOP 110384 Cobalamin-independent methionine synthase
2 1 SCOP 110630 Ppx/GppA phosphatase
2 2 SCOP 111284 Putative modulator of DNA gyrase, PmbA/TldD
2 2 SCOP 142701 RibD C-terminal domain-like
2 2 SCOP 142721 PyrH-like
1 1 SCOP 46566 Chaperone J-domain
1 1 SCOP 46610 Fe,Mn superoxide dismutase (SOD), N-terminal domain
1 1 SCOP 46947 Ribosomal protein S13
1 1 SCOP 47064 Ribosomal protein S15
1 1 SCOP 47241 Ferritin
1 1 SCOP 47253 Ribonucleotide reductase-like
1 1 SCOP 47324 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
1 1 SCOP 47447 Signal peptide-binding domain
1 1 SCOP 47786 NAD+-dependent DNA ligase, domain 3
1 1 SCOP 47974 Ribosomal protein S7
1 1 SCOP 48030 FliG
1 1 SCOP 48184 Acetohydroxy acid isomeroreductase (ketol-acid reductoisomerase, KARI)
1 1 SCOP 48593 GroEL chaperone, ATPase domain
1 1 SCOP 48614 Eukaryotic type heme oxygenase
1 1 SCOP 50114 C-terminal domain of ribosomal protein L2
1 1 SCOP 50130 GroES
1 1 SCOP 50136 Alcohol dehydrogenase-like, N-terminal domain
1 1 SCOP 50194 Ribosomal protein L14
1 1 SCOP 50277 Myf domain
1 1 SCOP 50325 Inorganic pyrophosphatase
1 1 SCOP 50342 CheW-like
1 1 SCOP 50461 Ribosomal protein L3
1 1 SCOP 50693 Pyruvoyl dependent aspartate decarboxylase, ADC
1 1 SCOP 51005 C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase
1 1 SCOP 51012 alpha-Amylases, C-terminal beta-sheet domain
1 1 SCOP 51162 UDP N-acetylglucosamine acyltransferase
1 1 SCOP 51171 GlmU C-terminal domain-like
1 1 SCOP 51174 gamma-carbonic anhydrase-like
1 1 SCOP 51231 Biotinyl/lipoyl-carrier proteins and domains
1 1 SCOP 51312 Type 1 signal peptidase
1 1 SCOP 51352 Triosephosphate isomerase (TIM)
1 1 SCOP 51372 D-ribulose-5-phosphate 3-epimerase
1 1 SCOP 51375 Decarboxylase
1 1 SCOP 51413 Inosine monophosphate dehydrogenase (IMPDH)
1 1 SCOP 51446 Amylase, catalytic domain
1 1 SCOP 51594 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase)
1 1 SCOP 51599 Class I DAHP synthetase
1 1 SCOP 51605 Enolase
1 1 SCOP 51622 Pyruvate kinase
1 1 SCOP 51691 NadC C-terminal domain-like
1 1 SCOP 51714 tRNA-guanine transglycosylase
1 1 SCOP 51718 Dihydropteroate synthetase
1 1 SCOP 51727 Uroporphyrinogen decarboxylase, UROD
1 1 SCOP 51731 Methylenetetrahydrofolate reductase
1 1 SCOP 51736 Alcohol dehydrogenase-like, C-terminal domain
1 1 SCOP 51883 Aminoacid dehydrogenase-like, C-terminal domain
1 1 SCOP 51900 CoA-binding domain
1 1 SCOP 52002 R1 subunit of ribonucleotide reductase, C-terminal domain
1 1 SCOP 52022 Carbamoyl phosphate synthetase, small subunit N-terminal domain
1 1 SCOP 52030 GroEL-like chaperone, apical domain
1 1 SCOP 52081 Ribosomal proteins L15p and L18e
1 1 SCOP 52097 Clp protease, ClpP subunit
1 1 SCOP 52100 Tail specific protease, catalytic domain
1 1 SCOP 52122 Lumazine synthase
1 1 SCOP 52147 Mug-like
1 1 SCOP 52152 FabD-like
1 1 SCOP 52162 Ribosomal protein L13
1 1 SCOP 52167 Ribosomal protein L4
1 1 SCOP 52173 CheY-related
1 1 SCOP 52256 N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
1 1 SCOP 52300 S-adenosylhomocystein hydrolase
1 1 SCOP 52314 Ribosomal protein S2
1 1 SCOP 52397 Adenylyltransferase
1 1 SCOP 52419 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
1 1 SCOP 52475 Pyruvate oxidase and decarboxylase, middle domain
1 1 SCOP 52491 Tubulin, GTPase domain
1 1 SCOP 52739 Methylesterase CheB, C-terminal domain
1 1 SCOP 52789 Low-molecular-weight phosphotyrosine protein phosphatases
1 1 SCOP 52918 Thioredoxin-like 2Fe-2S ferredoxin
1 1 SCOP 52944 ATP synthase (F1-ATPase), gamma subunit
1 1 SCOP 53138 Ribosomal protein L18 and S11
1 1 SCOP 53164 Hydrogenase maturating endopeptidase HybD
1 1 SCOP 53168 Purine and uridine phosphorylases
1 1 SCOP 53179 Peptidyl-tRNA hydrolase-like
1 1 SCOP 53201 Leucine aminopeptidase, C-terminal domain
1 1 SCOP 53214 LigB-like
1 1 SCOP 53245 MurCDEF C-terminal domain
1 1 SCOP 53255 Cofactor-dependent phosphoglycerate mutase
1 1 SCOP 53296 Phosphoribosylpyrophosphate synthetase-like
1 1 SCOP 53614 Ribokinase-like
1 1 SCOP 53620 Thiamin biosynthesis kinases
1 1 SCOP 53624 MurCDEF
1 1 SCOP 53629 Folylpolyglutamate synthetase
1 1 SCOP 53698 double-SIS domain
1 1 SCOP 53707 Formate dehydrogenase/DMSO reductase, domains 1-3
1 1 SCOP 53749 Phosphoglycerate kinase
1 1 SCOP 53760 Peptidoglycan biosynthesis glycosyltransferase MurG
1 1 SCOP 53791 Tetrapyrrole methylase
1 1 SCOP 53801 Ferrochelatase
1 1 SCOP 53914 Chalcone synthase-like
1 1 SCOP 54198 HIT (HINT, histidine triad) family of protein kinase-interacting proteins
1 1 SCOP 54212 Translational machinery components
1 1 SCOP 54224 DNA gyrase/MutL, second domain
1 1 SCOP 54365 Translation initiation factor IF3, N-terminal domain
1 1 SCOP 54369 Glutamine synthetase, N-terminal domain
1 1 SCOP 54632 CBS-domain pair
1 1 SCOP 54714 Elongation factor Ts (EF-Ts), dimerisation domain
1 1 SCOP 54720 Fe,Mn superoxide dismutase (SOD), C-terminal domain
1 1 SCOP 54737 Ribosomal protein L7/12, C-terminal domain
1 1 SCOP 54748 Ribosomal L11/L12e N-terminal domain
1 1 SCOP 54811 GMP synthetase C-terminal dimerisation domain
1 1 SCOP 54815 Prokaryotic type KH domain (KH-domain type II)
1 1 SCOP 54822 Ribosomal protein S3 C-terminal domain
1 1 SCOP 54827 Enolase N-terminal domain-like
1 1 SCOP 54884 Ferredoxin domains from multidomain proteins
1 1 SCOP 54920 Nucleoside diphosphate kinase, NDK
1 1 SCOP 54996 Ribosomal protein S6
1 1 SCOP 55000 Ribosomal protein S10
1 1 SCOP 55041 Molybdenum cofactor biosynthesis protein C, MoaC
1 1 SCOP 55084 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
1 1 SCOP 55121 Pseudouridine synthase I TruA
1 1 SCOP 55178 Ribosomal protein S4
1 1 SCOP 55187 Threonyl-tRNA synthetase (ThrRS), second 'additional' domain
1 1 SCOP 55195 Ribosome recycling factor, RRF
1 1 SCOP 55283 Ribosomal protein L5
1 1 SCOP 55299 YjgF/L-PSP
1 1 SCOP 55376 Glucose 6-phosphate dehydrogenase-like
1 1 SCOP 55621 GTP cyclohydrolase I
1 1 SCOP 55879 DNA gyrase/MutL, N-terminal domain
1 1 SCOP 55884 Histidine kinase
1 1 SCOP 55932 Glutamine synthetase catalytic domain
1 1 SCOP 56038 B3/B4 domain of PheRS, PheT
1 1 SCOP 56048 Ribosomal protein S8
1 1 SCOP 56054 Ribosomal protein L6
1 1 SCOP 56081 Succinyl-CoA synthetase, beta-chain, N-terminal domain
1 1 SCOP 56096 Adenylation domain of NAD+-dependent DNA ligase
1 1 SCOP 56105 SAICAR synthase
1 1 SCOP 56251 Proteasome subunits
1 1 SCOP 56328 Lactate & malate dehydrogenases, C-terminal domain
1 1 SCOP 56426 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain
1 1 SCOP 56530 FAH
1 1 SCOP 56673 DNA polymerase I
1 1 SCOP 56713 Prokaryotic type I DNA topoisomerase
1 1 SCOP 56720 Type II DNA topoisomerase
1 1 SCOP 56732 DNA primase DnaG catalytic core
1 1 SCOP 56753 D-aminoacid aminotransferase-like PLP-dependent enzymes
1 1 SCOP 56763 Nickel-iron hydrogenase, large subunit
1 1 SCOP 56809 Ribosomal protein L1
1 1 SCOP 56955 Outer membrane efflux proteins (OEP)
1 1 SCOP 63801 ATP sulfurylase N-terminal domain
1 1 SCOP 63883 MoeA N-terminal region -like
1 1 SCOP 63893 Pyridoxine 5'-phosphate synthase
1 1 SCOP 63971 Inosicase
1 1 SCOP 63976 Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC)
1 1 SCOP 63979 ATP sulfurylase catalytic domain
1 1 SCOP 64006 Undecaprenyl diphosphate synthase
1 1 SCOP 64117 tRNA(1-methyladenosine) methyltransferase-like
1 1 SCOP 64198 AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC
1 1 SCOP 64264 Prokaryotic ribosomal protein L17
1 1 SCOP 64372 3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB
1 1 SCOP 64485 RNA-polymerase beta
1 1 SCOP 64490 RNA-polymerase beta-prime
1 1 SCOP 68901 Cytidylytransferase
1 1 SCOP 69066 RNase III catalytic domain-like
1 1 SCOP 69337 Alpha subunit of glutamate synthase, C-terminal domain
1 1 SCOP 69557 Spermidine synthase
1 1 SCOP 69560 Mycolic acid cyclopropane synthase
1 1 SCOP 69573 Molybdenum cofactor biosynthesis protein MoeB
1 1 SCOP 69599 mono-SIS domain
1 1 SCOP 69602 L-histidinol dehydrogenase HisD
1 1 SCOP 69746 Pseudouridine synthase II TruB
1 1 SCOP 69766 IpsF-like
1 1 SCOP 69865 Argininosuccinate synthetase, C-terminal domain
1 1 SCOP 69892 Iron-containing alcohol dehydrogenase
1 1 SCOP 74732 Ribosomal protein L20
1 1 SCOP 74983 Small protein B (SmpB)
1 1 SCOP 75073 Hydantoinase (dihydropyrimidinase), catalytic domain
1 1 SCOP 75292 YjeF C-terminal domain-like
1 1 SCOP 75297 N-acetyl-l-glutamate kinase
1 1 SCOP 75305 Amidase signature (AS) enzymes
1 1 SCOP 75323 Exonuclease RecJ
1 1 SCOP 75434 Divalent ion tolerance proteins CutA (CutA1)
1 1 SCOP 75459 Pseudouridine synthase RsuA/RluD
1 1 SCOP 75626 YebC-like
1 1 SCOP 81642 Cytochrome b of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
1 1 SCOP 81659 Metal cation-transporting ATPase, ATP-binding domain N
1 1 SCOP 81768 Pre-protein crosslinking domain of SecA
1 1 SCOP 81887 Helical scaffold and wing domains of SecA
1 1 SCOP 81892 Poly A polymerase C-terminal region-like
1 1 SCOP 82005 N-utilization substance G protein NusG, insert domain
1 1 SCOP 82052 Obg GTP-binding protein N-terminal domain
1 1 SCOP 82191 Acireductone dioxygenase
1 1 SCOP 82258 SAH/MTA deaminase-like
1 1 SCOP 82267 TatD Mg-dependent DNase-like
1 1 SCOP 82336 Shikimate dehydrogenase-like
1 1 SCOP 82359 PP-loop ATPase
1 1 SCOP 82583 G domain-linked domain
1 1 SCOP 82661 Poly A polymerase head domain-like
1 1 SCOP 82680 N-utilization substance G protein NusG, N-terminal domain
1 1 SCOP 88683 Eukaryotic ODC-like
1 1 SCOP 88724 Pyruvate oxidase and decarboxylase Pyr module
1 1 SCOP 88735 TK-like Pyr module
1 1 SCOP 88749 Pyruvate oxidase and decarboxylase PP module
1 1 SCOP 88760 TK-like PP module
1 1 SCOP 88854 Protein kinases, catalytic subunit
1 1 SCOP 88947 Sigma2 domain of RNA polymerase sigma factors
1 1 SCOP 89013 4-alpha-glucanotransferase, domain 2
1 1 SCOP 89361 HesB-like domain
1 1 SCOP 89503 Ketopantoate hydroxymethyltransferase PanB
1 1 SCOP 89554 4-alpha-glucanotransferase, N-terminal domain
1 1 SCOP 89624 Ribose/Galactose isomerase RpiB/AlsB
1 1 SCOP 89629 tRNA(m1G37)-methyltransferase TrmD
1 1 SCOP 89800 Deoxycytidylate deaminase-like
1 1 SCOP 89827 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase LpxC
1 1 SCOP 100921 Heat shock protein 70kD (HSP70), peptide-binding domain
1 1 SCOP 101340 HD domain
1 1 SCOP 101354 Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
1 1 SCOP 102115 Biotin synthase
1 1 SCOP 102118 Oxygen-independent coproporphyrinogen III oxidase HemN
1 1 SCOP 102406 MoCo carrier protein-like
1 1 SCOP 102656 PdxA-like
1 1 SCOP 102660 PlsX-like
1 1 SCOP 102769 ATP-dependent protease Lon (La), catalytic domain
1 1 SCOP 102928 NifU/IscU domain
1 1 SCOP 102945 RelA/SpoT domain
1 1 SCOP 103132 Predicted metal-dependent hydrolase
1 1 SCOP 103264 Chorismate synthase, AroC
1 1 SCOP 109756 PhoU-like
1 1 SCOP 110325 Ribosomal L27 protein
1 1 SCOP 110388 MoCo biosynthesis proteins
1 1 SCOP 110400 ThiG-like
1 1 SCOP 110513 IF2B-like
1 1 SCOP 110734 Glycosyl transferases group 1
1 1 SCOP 110902 FabZ-like
1 1 SCOP 110933 GlnE-like domain
1 1 SCOP 111039 YjbQ-like
1 1 SCOP 111219 ArgJ-like
1 1 SCOP 111250 Sulfolobus fructose-1,6-bisphosphatase-like
1 1 SCOP 111305 Recombination protein RecR
1 1 SCOP 111332 NAD kinase-like
1 1 SCOP 111338 QueA-like
1 1 SCOP 111353 Ammonium transporter
1 1 SCOP 117397 TM1631-like
1 1 SCOP 117888 Ribosomal protein L16p
1 1 SCOP 140991 FtsH protease domain-like
1 1 SCOP 141245 Ribosomal protein L19
1 1 SCOP 141368 UbiD middle domain-like
1 1 SCOP 141735 HisI-like
1 1 SCOP 142020 Nqo1 FMN-binding domain-like
1 1 SCOP 142186 Enolase-phosphatase E1
1 1 SCOP 142339 CofD-like
1 1 SCOP 142696 RibA-like
1 1 SCOP 142755 NadA-like
1 1 SCOP 143448 AMMECR1-like
1 1 SCOP 143598 YojJ-like
1 1 SCOP 143812 GatB/GatE catalytic domain-like
1 1 SCOP 143927 beta-CASP RNA-metabolising hydrolases
1 1 SCOP 143969 UbiD C-terminal domain-like
1 1 SCOP 143976 lvD/EDD N-terminal domain-like
1 1 SCOP 144031 Nq06-like
1 1 SCOP 159112 RNB domain-like
1 1 SCOP 159697 TRM1-like
1 1 SCOP 159720 mannose-1-phosphate guanylyl transferase
1 1 SCOP 159832 PBP transglycosylase domain-like

The following families have one or more weak hits: