Family Assignments

Domains Proteins SCOP Link Families
48 48 SCOP 88854 Protein kinases, catalytic subunit
27 20 SCOP 81268 Tandem AAA-ATPase domain
26 26 SCOP 52592 G proteins
21 17 SCOP 81269 Extended AAA-ATPase domain
13 13 SCOP 52641 Motor proteins
13 7 SCOP 53068 Actin/HSP70
13 13 SCOP 56251 Proteasome subunits
12 8 SCOP 52686 ABC transporter ATPase domain-like
11 11 SCOP 55682 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
10 10 SCOP 54496 UBC-related
9 9 SCOP 52375 Class I aminoacyl-tRNA synthetases (RS), catalytic domain
8 8 SCOP 56310 Protein serine/threonine phosphatase
7 7 SCOP 47114 Nucleosome core histones
7 7 SCOP 50979 WD40-repeat
7 7 SCOP 63412 MPP-like
6 6 SCOP 50892 Cyclophilin (peptidylprolyl isomerase)
6 2 SCOP 53739 Phosphoglucomutase, first 3 domains
5 5 SCOP 47502 Calmodulin-like
5 5 SCOP 52670 RecA protein-like (ATPase-domain)
5 3 SCOP 54237 Ubiquitin-related
4 4 SCOP 48372 Armadillo repeat
4 4 SCOP 52541 Nucleotide and nucleoside kinases
4 2 SCOP 53785 Phosphofructokinase
4 4 SCOP 54002 Papain-like
4 4 SCOP 74771 Clathrin adaptor core protein
4 4 SCOP 82568 Ubiquitin carboxyl-terminal hydrolase, UCH
4 4 SCOP 117702 Polypeptide N-acetylgalactosaminyltransferase 1, N-terminal domain
3 3 SCOP 48426 Sec7 domain
3 3 SCOP 48446 14-3-3 protein
3 3 SCOP 50448 Elongation factors
3 3 SCOP 51751 Tyrosine-dependent oxidoreductases
3 3 SCOP 51830 Formate/glycerate dehydrogenases, NAD-domain
3 3 SCOP 52491 Tubulin, GTPase domain
3 3 SCOP 52652 Nitrogenase iron protein-like
3 3 SCOP 53351 Arginine methyltransferase
3 3 SCOP 55730 N-acetyl transferase, NAT
3 1 SCOP 55974 S-adenosylmethionine synthetase
3 3 SCOP 56816 Sec1/munc18-like (SM) proteins
3 3 SCOP 64485 RNA-polymerase beta
3 3 SCOP 64490 RNA-polymerase beta-prime
3 3 SCOP 89125 Nop domain
3 3 SCOP 100921 Heat shock protein 70kD (HSP70), peptide-binding domain
2 1 SCOP 47924 Ypt/Rab-GAP domain of gyp1p
2 2 SCOP 48246 Protein prenyltransferases
2 2 SCOP 48440 Protein prenylyltransferase
2 2 SCOP 48548 PDEase
2 2 SCOP 49448 Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor
2 2 SCOP 50183 Sm motif of small nuclear ribonucleoproteins, SNRNP
2 2 SCOP 50282 Cold shock DNA-binding domain-like
2 2 SCOP 50646 Pepsin-like
2 2 SCOP 51396 FMN-linked oxidoreductases
2 2 SCOP 51446 Amylase, catalytic domain
2 2 SCOP 51848 LDH N-terminal domain-like
2 2 SCOP 52034 Group II chaperonin (CCT, TRIC), apical domain
2 2 SCOP 52318 Class I glutamine amidotransferases (GAT)
2 2 SCOP 52403 N-type ATP pyrophosphatases
2 2 SCOP 52484 Transhydrogenase domain III (dIII)
2 2 SCOP 52744 Subtilases
2 2 SCOP 52773 Histone deacetylase, HDAC
2 2 SCOP 53272 Phosphoribosyltransferases (PRTases)
2 2 SCOP 53417 GABA-aminotransferase-like
2 2 SCOP 54212 Translational machinery components
2 2 SCOP 54920 Nucleoside diphosphate kinase, NDK
2 1 SCOP 54981 EF-G/eEF-2 domains III and V
2 2 SCOP 55308 Tubulin, C-terminal domain
2 1 SCOP 55748 N-myristoyl transferase, NMT
2 2 SCOP 55875 Heat shock protein 90, HSP90, N-terminal domain
2 2 SCOP 55879 DNA gyrase/MutL, N-terminal domain
2 2 SCOP 55921 Creatinase/aminopeptidase
2 1 SCOP 55946 TATA-box binding protein (TBP), C-terminal domain
2 2 SCOP 55958 Phosphoglucomutase, C-terminal domain
2 1 SCOP 55983 DNA polymerase processivity factor
2 2 SCOP 56205 Hect, E3 ligase catalytic domain
2 2 SCOP 56328 Lactate & malate dehydrogenases, C-terminal domain
2 2 SCOP 56673 DNA polymerase I
2 2 SCOP 57799 Casein kinase II beta subunit
2 2 SCOP 75521 Clathrin coat assembly domain
2 2 SCOP 81605 PP2C-like
2 2 SCOP 81656 Meta-cation ATPase, catalytic domain P
2 2 SCOP 82458 Trunk domain of Sec23/24
2 1 SCOP 88771 PFOR PP module
2 1 SCOP 89572 Biotin dependent carboxylase carboxyltransferase domain
2 2 SCOP 102755 Hsp90 middle domain
2 2 SCOP 118076 TRAPP components
2 2 SCOP 143927 beta-CASP RNA-metabolising hydrolases
1 1 SCOP 46566 Chaperone J-domain
1 1 SCOP 46610 Fe,Mn superoxide dismutase (SOD), N-terminal domain
1 1 SCOP 46925 RNA polymerase subunit RPB10
1 1 SCOP 47217 Proteasome activator
1 1 SCOP 47253 Ribonucleotide reductase-like
1 1 SCOP 47447 Signal peptide-binding domain
1 1 SCOP 47577 Calponin-homology domain, CH-domain
1 1 SCOP 47662 t-snare proteins
1 1 SCOP 47808 5' to 3' exonuclease, C-terminal subdomain
1 1 SCOP 47918 C-terminal domain of alpha and beta subunits of F1 ATP synthase
1 1 SCOP 47974 Ribosomal protein S7
1 1 SCOP 48390 Clathrin heavy chain proximal leg segment
1 1 SCOP 48404 Ankyrin repeat
1 1 SCOP 48577 Isoprenyl diphosphate synthases
1 1 SCOP 49999 Amine oxidase catalytic domain
1 1 SCOP 50114 C-terminal domain of ribosomal protein L2
1 1 SCOP 50136 Alcohol dehydrogenase-like, N-terminal domain
1 1 SCOP 50194 Ribosomal protein L14
1 1 SCOP 50277 Myf domain
1 1 SCOP 50307 DNA ligase/mRNA capping enzyme postcatalytic domain
1 1 SCOP 50325 Inorganic pyrophosphatase
1 1 SCOP 50461 Ribosomal protein L3
1 1 SCOP 50466 EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
1 1 SCOP 50678 ValRS/IleRS/LeuRS editing domain
1 1 SCOP 50708 Cdc48 N-terminal domain-like
1 1 SCOP 50719 Gln-tRNA synthetase (GlnRS), C-terminal (anticodon-binding) domain
1 1 SCOP 50764 Ran-binding domain
1 1 SCOP 50990 Clathrin heavy-chain terminal domain
1 1 SCOP 51191 Type I phosphomannose isomerase
1 1 SCOP 51247 BC C-terminal domain-like
1 1 SCOP 51284 dUTPase-like
1 1 SCOP 51352 Triosephosphate isomerase (TIM)
1 1 SCOP 51413 Inosine monophosphate dehydrogenase (IMPDH)
1 1 SCOP 51427 "Hypothetical" protein ybl036c
1 1 SCOP 51557 Adenosine/AMP deaminase
1 1 SCOP 51570 Class I aldolase
1 1 SCOP 51605 Enolase
1 1 SCOP 51622 Pyruvate kinase
1 1 SCOP 51632 Phosphoenolpyruvate carboxylase
1 1 SCOP 51659 Endonuclease IV
1 1 SCOP 51696 Mammalian PLC
1 1 SCOP 51714 tRNA-guanine transglycosylase
1 1 SCOP 51800 Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
1 1 SCOP 51883 Aminoacid dehydrogenase-like, C-terminal domain
1 1 SCOP 51931 GDI-like N domain
1 1 SCOP 51943 FAD/NAD-linked reductases, N-terminal and central domains
1 1 SCOP 52002 R1 subunit of ribonucleotide reductase, C-terminal domain
1 1 SCOP 52030 GroEL-like chaperone, apical domain
1 1 SCOP 52142 Uracil-DNA glycosylase
1 1 SCOP 52167 Ribosomal protein L4
1 1 SCOP 52300 S-adenosylhomocystein hydrolase
1 1 SCOP 52314 Ribosomal protein S2
1 1 SCOP 52441 BC N-terminal domain-like
1 1 SCOP 52468 Deoxyhypusine synthase, DHS
1 1 SCOP 52508 Homo-oligomeric flavin-containing Cys decarboxylases, HFCD
1 1 SCOP 52584 Phosphoribulokinase/pantothenate kinase
1 1 SCOP 52800 Dual specificity phosphatase-like
1 1 SCOP 52895 spliceosomal protein U5-15Kd
1 1 SCOP 52901 Glutathione peroxidase-like
1 1 SCOP 52931 Pyruvate-ferredoxin oxidoreductase, PFOR, domain II
1 1 SCOP 52973 ITPase (Ham1)
1 1 SCOP 53045 5' to 3' exonuclease catalytic domain
1 1 SCOP 53083 Hexokinase
1 1 SCOP 53118 DnaQ-like 3'-5' exonuclease
1 1 SCOP 53143 ERF1/Dom34 middle domain-like
1 1 SCOP 53201 Leucine aminopeptidase, C-terminal domain
1 1 SCOP 53240 Malic enzyme N-domain
1 1 SCOP 53255 Cofactor-dependent phosphoglycerate mutase
1 1 SCOP 53324 Pyruvate-ferredoxin oxidoreductase, PFOR, domain III
1 1 SCOP 53342 Fibrillarin homologue
1 1 SCOP 53402 Cystathionine synthase-like
1 1 SCOP 53461 UDP-glucose pyrophosphorylase
1 1 SCOP 53598 Dihydrofolate reductases
1 1 SCOP 53614 Ribokinase-like
1 1 SCOP 53687 Tryptophan synthase beta subunit-like PLP-dependent enzymes
1 1 SCOP 53698 double-SIS domain
1 1 SCOP 53701 Phosphoglucose isomerase, PGI
1 1 SCOP 53721 ALDH-like
1 1 SCOP 53749 Phosphoglycerate kinase
1 1 SCOP 53766 Oligosaccharide phosphorylase
1 1 SCOP 53791 Tetrapyrrole methylase
1 1 SCOP 54050 Ubiquitin carboxyl-terminal hydrolase UCH-L
1 1 SCOP 54054 Adenain-like
1 1 SCOP 54193 L15e
1 1 SCOP 54224 DNA gyrase/MutL, second domain
1 1 SCOP 54431 NTF2-like
1 1 SCOP 54535 FKBP immunophilin/proline isomerase
1 1 SCOP 54586 Cdc48 domain 2-like
1 1 SCOP 54649 DLC
1 1 SCOP 54687 Ribosomal protein L10e
1 1 SCOP 54720 Fe,Mn superoxide dismutase (SOD), C-terminal domain
1 1 SCOP 54748 Ribosomal L11/L12e N-terminal domain
1 1 SCOP 54815 Prokaryotic type KH domain (KH-domain type II)
1 1 SCOP 54827 Enolase N-terminal domain-like
1 1 SCOP 55160 eIF1-like
1 1 SCOP 55187 Threonyl-tRNA synthetase (ThrRS), second 'additional' domain
1 1 SCOP 55283 Ribosomal protein L5
1 1 SCOP 55288 RPB5
1 1 SCOP 55294 RPB6
1 1 SCOP 55316 L30e/L7ae ribosomal proteins
1 1 SCOP 55323 ERF1/Dom34 C-terminal domain-like
1 1 SCOP 55348 GAPDH-like
1 1 SCOP 55425 FAD/NAD-linked reductases, dimerisation (C-terminal) domain
1 1 SCOP 55482 N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1
1 1 SCOP 55762 Cofilin-like
1 1 SCOP 55817 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain
1 1 SCOP 55832 Thymidylate synthase/dCMP hydroxymethylase
1 1 SCOP 55910 Ribosome anti-association factor eIF6 (aIF6)
1 1 SCOP 55932 Glutamine synthetase catalytic domain
1 1 SCOP 56048 Ribosomal protein S8
1 1 SCOP 56067 BC ATP-binding domain-like
1 1 SCOP 56092 ATP-dependent DNA ligase catalytic domain
1 1 SCOP 56108 Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta
1 1 SCOP 56171 Phoshoinositide 3-kinase (PI3K), catalytic domain
1 1 SCOP 56236 Class II glutamine amidotransferases
1 1 SCOP 56361 Eukaryotic DNA topoisomerase I, catalytic core
1 1 SCOP 56554 Insert subdomain of RNA polymerase alpha subunit
1 1 SCOP 56713 Prokaryotic type I DNA topoisomerase
1 1 SCOP 56720 Type II DNA topoisomerase
1 1 SCOP 56742 Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment
1 1 SCOP 56802 Acetyl-CoA synthetase-like
1 1 SCOP 56809 Ribosomal protein L1
1 1 SCOP 57851 RING finger domain, C3HC4
1 1 SCOP 63873 Translationally controlled tumor protein TCTP (histamine-releasing factor)
1 1 SCOP 64006 Undecaprenyl diphosphate synthase
1 1 SCOP 69341 C-terminal domain of adenylylcyclase associated protein
1 1 SCOP 69501 DTD-like
1 1 SCOP 69573 Molybdenum cofactor biosynthesis protein MoeB
1 1 SCOP 69746 Pseudouridine synthase II TruB
1 1 SCOP 69815 Tyrosyl-DNA phosphodiesterase TDP1
1 1 SCOP 69892 Iron-containing alcohol dehydrogenase
1 1 SCOP 75434 Divalent ion tolerance proteins CutA (CutA1)
1 1 SCOP 75633 Cullin homology domain
1 1 SCOP 81380 Skp1 dimerisation domain-like
1 1 SCOP 81589 Poly(A) polymerase, PAP, N-terminal domain
1 1 SCOP 81630 Poly(A) polymerase, PAP, middle domain
1 1 SCOP 81659 Metal cation-transporting ATPase, ATP-binding domain N
1 1 SCOP 81664 Calcium ATPase, transmembrane domain M
1 1 SCOP 81812 Helical domain of Sec23/24
1 1 SCOP 81838 BEACH domain
1 1 SCOP 82388 Predicted hydrolases Cof
1 1 SCOP 82583 G domain-linked domain
1 1 SCOP 82755 C-terminal, gelsolin-like domain of Sec23/24
1 1 SCOP 82767 Sedlin (SEDL)
1 1 SCOP 88724 Pyruvate oxidase and decarboxylase Pyr module
1 1 SCOP 88746 PFOR Pyr module
1 1 SCOP 88749 Pyruvate oxidase and decarboxylase PP module
1 1 SCOP 88784 rRNA adenine dimethylase-like
1 1 SCOP 89508 Glycerophosphoryl diester phosphodiesterase
1 1 SCOP 89716 XPF/Rad1/Mus81 nuclease
1 1 SCOP 89763 Ubiquitin activating enzymes (UBA)
1 1 SCOP 89943 eEF1-gamma domain
1 1 SCOP 100888 Lesion bypass DNA polymerase (Y-family), catalytic domain
1 1 SCOP 100908 MIF4G domain-like
1 1 SCOP 101153 Mob1/phocein
1 1 SCOP 101354 Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
1 1 SCOP 101448 Formin homology 2 domain (FH2 domain)
1 1 SCOP 101547 ASF1-like
1 1 SCOP 101888 Apyrase
1 1 SCOP 102422 Myotubularin-like phosphatases
1 1 SCOP 102463 Peptidyl-tRNA hydrolase II
1 1 SCOP 102492 CAF1-like ribonuclease
1 1 SCOP 102575 NOL1/NOP2/sun
1 1 SCOP 102646 CoaB-like
1 1 SCOP 102928 NifU/IscU domain
1 1 SCOP 103492 Preprotein translocase SecY subunit
1 1 SCOP 103507 Mitochondrial carrier
1 1 SCOP 110509 NLI interacting factor-like phosphatase
1 1 SCOP 110832 Nip7p homolog, N-terminal domain
1 1 SCOP 111233 YfcE-like
1 1 SCOP 117002 Exportin HEAT-like repeat
1 1 SCOP 117019 ATP-dependent DNA ligase DNA-binding domain
1 1 SCOP 118197 YaeB-like
1 1 SCOP 118204 Vacuolar ATP synthase subunit C
1 1 SCOP 140819 B56-like
1 1 SCOP 140985 PTPA-like
1 1 SCOP 140991 FtsH protease domain-like
1 1 SCOP 141436 SSRP1-like
1 1 SCOP 141679 MAL13P1.257-like
1 1 SCOP 142721 PyrH-like
1 1 SCOP 143072 UFC1-like
1 1 SCOP 143114 NAP-like
1 1 SCOP 158782 HAT/Suf repeat
1 1 SCOP 159112 RNB domain-like
1 1 SCOP 159513 EMG1/NEP1-like
1 1 SCOP 159638 Prp8 beta-finger domain-like
1 1 SCOP 161204 Zf-UBP

The following families have one or more weak hits: