Family Assignments

Domains Proteins SCOP Link Families
68 65 SCOP 52686 ABC transporter ATPase domain-like
17 17 SCOP 53851 Phosphate binding protein-like
13 10 SCOP 81268 Tandem AAA-ATPase domain
12 12 SCOP 53687 Tryptophan synthase beta subunit-like PLP-dependent enzymes
11 11 SCOP 51751 Tyrosine-dependent oxidoreductases
11 11 SCOP 53417 GABA-aminotransferase-like
11 11 SCOP 55921 Creatinase/aminopeptidase
11 8 SCOP 81269 Extended AAA-ATPase domain
9 9 SCOP 53402 Cystathionine synthase-like
8 8 SCOP 52318 Class I glutamine amidotransferases (GAT)
8 8 SCOP 52375 Class I aminoacyl-tRNA synthetases (RS), catalytic domain
8 8 SCOP 52652 Nitrogenase iron protein-like
7 7 SCOP 51431 Aldo-keto reductases (NADP)
7 7 SCOP 52592 G proteins
7 7 SCOP 53384 AAT-like
7 7 SCOP 55682 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
7 7 SCOP 75305 Amidase signature (AS) enzymes
6 6 SCOP 47204 Medium chain acyl-CoA dehydrogenase-like, C-terminal domain
6 6 SCOP 48311 Aldehyde ferredoxin oxidoreductase, C-terminal domains
6 6 SCOP 51868 6-phosphogluconate dehydrogenase-like, N-terminal domain
6 6 SCOP 52103 Crotonase-like
6 6 SCOP 53721 ALDH-like
6 6 SCOP 56229 Aldehyde ferredoxin oxidoreductase, N-terminal domain
6 6 SCOP 56646 Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains
6 6 SCOP 56802 Acetyl-CoA synthetase-like
6 6 SCOP 161099 MetI-like
5 5 SCOP 51570 Class I aldolase
5 5 SCOP 52744 Subtilases
4 4 SCOP 47241 Ferritin
4 4 SCOP 51396 FMN-linked oxidoreductases
4 4 SCOP 51609 D-glucarate dehydratase-like
4 4 SCOP 51883 Aminoacid dehydrogenase-like, C-terminal domain
4 4 SCOP 52403 N-type ATP pyrophosphatases
4 4 SCOP 52769 Arginase-like amidino hydrolases
4 4 SCOP 53204 Bacterial dinuclear zinc exopeptidases
4 3 SCOP 56067 BC ATP-binding domain-like
4 4 SCOP 56530 FAH
4 2 SCOP 89572 Biotin dependent carboxylase carboxyltransferase domain
4 4 SCOP 110436 Ornithine cyclodeaminase-like
3 3 SCOP 48558 L-aspartase/fumarase
3 1 SCOP 49550 Multidomain cupredoxins
3 3 SCOP 51830 Formate/glycerate dehydrogenases, NAD-domain
3 3 SCOP 52211 Succinyl-CoA synthetase domains
3 2 SCOP 52441 BC N-terminal domain-like
3 3 SCOP 52670 RecA protein-like (ATPase-domain)
3 3 SCOP 53168 Purine and uridine phosphorylases
3 3 SCOP 53614 Ribokinase-like
3 3 SCOP 53660 Dimeric isocitrate & isopropylmalate dehydrogenases
3 3 SCOP 55308 Tubulin, C-terminal domain
3 3 SCOP 56236 Class II glutamine amidotransferases
3 3 SCOP 56251 Proteasome subunits
3 3 SCOP 56323 ADC synthase
3 3 SCOP 69222 PepX C-terminal domain-like
3 3 SCOP 82258 SAH/MTA deaminase-like
3 3 SCOP 82264 D-aminoacylase, catalytic domain
3 3 SCOP 89797 CoA-transferase family III (CaiB/BaiF)
2 2 SCOP 48265 Cytochrome P450
2 2 SCOP 48335 DNA repair protein MutS, domain III
2 2 SCOP 48596 Group II chaperonin (CCT, TRIC), ATPase domain
2 2 SCOP 50105 Ribosomal proteins L24p and L21e
2 2 SCOP 50448 Elongation factors
2 2 SCOP 50466 EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
2 2 SCOP 51367 Histidine biosynthesis enzymes
2 2 SCOP 51381 Tryptophan biosynthesis enzymes
2 2 SCOP 51638 HpcH/HpaI aldolase
2 2 SCOP 51704 Methylmalonyl-CoA mutase, N-terminal (CoA-binding) domain
2 2 SCOP 51913 FAD-linked reductases, N-terminal domain
2 2 SCOP 52034 Group II chaperonin (CCT, TRIC), apical domain
2 2 SCOP 52081 Ribosomal proteins L15p and L18e
2 2 SCOP 52491 Tubulin, GTPase domain
2 1 SCOP 52827 Multidomain sulfurtransferase (rhodanese)
2 1 SCOP 53068 Actin/HSP70
2 1 SCOP 53089 Glycerol kinase
2 2 SCOP 53224 Aminoacid dehydrogenases
2 2 SCOP 53272 Phosphoribosyltransferases (PRTases)
2 2 SCOP 53487 Carboxylesterase
2 2 SCOP 53672 Aspartate/ornithine carbamoyltransferase
2 2 SCOP 53698 double-SIS domain
2 2 SCOP 53707 Formate dehydrogenase/DMSO reductase, domains 1-3
2 2 SCOP 53733 Aconitase iron-sulfur domain
2 1 SCOP 53902 Thiolase-related
2 2 SCOP 54224 DNA gyrase/MutL, second domain
2 2 SCOP 55327 PurM N-terminal domain-like
2 2 SCOP 55425 FAD/NAD-linked reductases, dimerisation (C-terminal) domain
2 2 SCOP 55505 Neurolysin-like
2 2 SCOP 55879 DNA gyrase/MutL, N-terminal domain
2 1 SCOP 56054 Ribosomal protein L6
2 2 SCOP 56187 CO dehydrogenase flavoprotein N-terminal domain-like
2 2 SCOP 56673 DNA polymerase I
2 2 SCOP 56753 D-aminoacid aminotransferase-like PLP-dependent enzymes
2 2 SCOP 63883 MoeA N-terminal region -like
2 2 SCOP 64485 RNA-polymerase beta
2 2 SCOP 64490 RNA-polymerase beta-prime
2 1 SCOP 74656 CoA transferase alpha subunit-like
2 1 SCOP 74753 Catalase-peroxidase KatG
2 2 SCOP 75073 Hydantoinase (dihydropyrimidinase), catalytic domain
2 2 SCOP 81441 Cytochrome c oxidase subunit I-like
2 2 SCOP 88724 Pyruvate oxidase and decarboxylase Pyr module
2 2 SCOP 101340 HD domain
2 2 SCOP 109756 PhoU-like
2 2 SCOP 141131 Acetamidase/Formamidase-like
2 2 SCOP 142678 Glycine dehydrogenase subunits (GDC-P)
2 2 SCOP 143812 GatB/GatE catalytic domain-like
2 2 SCOP 143927 beta-CASP RNA-metabolising hydrolases
2 2 SCOP 144053 Thermophilic metalloprotease (M29)
1 1 SCOP 46562 Ribosomal protein L29 (L29p)
1 1 SCOP 46907 Ribosomal protein L11, C-terminal domain
1 1 SCOP 47253 Ribonucleotide reductase-like
1 1 SCOP 47786 NAD+-dependent DNA ligase, domain 3
1 1 SCOP 47974 Ribosomal protein S7
1 1 SCOP 48141 Ribosomal protein L19 (L19e)
1 1 SCOP 48174 Cryptochrome/photolyase FAD-binding domain
1 1 SCOP 48184 Acetohydroxy acid isomeroreductase (ketol-acid reductoisomerase, KARI)
1 1 SCOP 48257 Citrate synthase
1 1 SCOP 48577 Isoprenyl diphosphate synthases
1 1 SCOP 50101 Nitrile hydratase beta chain
1 1 SCOP 50114 C-terminal domain of ribosomal protein L2
1 1 SCOP 50194 Ribosomal protein L14
1 1 SCOP 50282 Cold shock DNA-binding domain-like
1 1 SCOP 50325 Inorganic pyrophosphatase
1 1 SCOP 50461 Ribosomal protein L3
1 1 SCOP 50495 Prokaryotic proteases
1 1 SCOP 50678 ValRS/IleRS/LeuRS editing domain
1 1 SCOP 50892 Cyclophilin (peptidylprolyl isomerase)
1 1 SCOP 50975 Nitrous oxide reductase, N-terminal domain
1 1 SCOP 51165 Tetrahydrodipicolinate-N-succinlytransferase, THDP-succinlytransferase, DapD
1 1 SCOP 51231 Biotinyl/lipoyl-carrier proteins and domains
1 1 SCOP 51284 dUTPase-like
1 1 SCOP 51352 Triosephosphate isomerase (TIM)
1 1 SCOP 51413 Inosine monophosphate dehydrogenase (IMPDH)
1 1 SCOP 51420 Alanine racemase-like, N-terminal domain
1 1 SCOP 51594 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase)
1 1 SCOP 51605 Enolase
1 1 SCOP 51622 Pyruvate kinase
1 1 SCOP 51659 Endonuclease IV
1 1 SCOP 51687 F420 dependent oxidoreductases
1 1 SCOP 51691 NadC C-terminal domain-like
1 1 SCOP 51714 tRNA-guanine transglycosylase
1 1 SCOP 51718 Dihydropteroate synthetase
1 1 SCOP 51727 Uroporphyrinogen decarboxylase, UROD
1 1 SCOP 51736 Alcohol dehydrogenase-like, C-terminal domain
1 1 SCOP 51800 Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
1 1 SCOP 51848 LDH N-terminal domain-like
1 1 SCOP 51900 CoA-binding domain
1 1 SCOP 51934 Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain
1 1 SCOP 51943 FAD/NAD-linked reductases, N-terminal and central domains
1 1 SCOP 52002 R1 subunit of ribonucleotide reductase, C-terminal domain
1 1 SCOP 52043 Ribosomal protein L32e
1 1 SCOP 52147 Mug-like
1 1 SCOP 52157 Initiation factor IF2/eIF5b, domain 3
1 1 SCOP 52162 Ribosomal protein L13
1 1 SCOP 52167 Ribosomal protein L4
1 1 SCOP 52243 Cobalamin (vitamin B12)-binding domain
1 1 SCOP 52256 N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
1 1 SCOP 52300 S-adenosylhomocystein hydrolase
1 1 SCOP 52314 Ribosomal protein S2
1 1 SCOP 52397 Adenylyltransferase
1 1 SCOP 52419 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
1 1 SCOP 52426 Cryptochrome/photolyase, N-terminal domain
1 1 SCOP 52432 ETFP subunits
1 1 SCOP 52468 Deoxyhypusine synthase, DHS
1 1 SCOP 52471 C-terminal domain of the electron transfer flavoprotein alpha subunit
1 1 SCOP 52541 Nucleotide and nucleoside kinases
1 1 SCOP 52584 Phosphoribulokinase/pantothenate kinase
1 1 SCOP 52773 Histone deacetylase, HDAC
1 1 SCOP 52778 CAT-like
1 1 SCOP 52901 Glutathione peroxidase-like
1 1 SCOP 52926 Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain
1 1 SCOP 52955 Anticodon-binding domain of Class II aaRS
1 1 SCOP 52973 ITPase (Ham1)
1 1 SCOP 53045 5' to 3' exonuclease catalytic domain
1 1 SCOP 53099 Ribonuclease H
1 1 SCOP 53138 Ribosomal protein L18 and S11
1 1 SCOP 53183 Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)
1 1 SCOP 53235 Tetrahydrofolate dehydrogenase/cyclohydrolase
1 1 SCOP 53240 Malic enzyme N-domain
1 1 SCOP 53329 Formyltransferase
1 1 SCOP 53339 RNA methyltransferase FtsJ
1 1 SCOP 53342 Fibrillarin homologue
1 1 SCOP 53464 glucose-1-phosphate thymidylyltransferase
1 1 SCOP 53496 Prolyl oligopeptidase, C-terminal domain
1 1 SCOP 53509 Proline iminopeptidase-like
1 1 SCOP 53598 Dihydrofolate reductases
1 1 SCOP 53620 Thiamin biosynthesis kinases
1 1 SCOP 53629 Folylpolyglutamate synthetase
1 1 SCOP 53640 AraD-like aldolase/epimerase
1 1 SCOP 53701 Phosphoglucose isomerase, PGI
1 1 SCOP 53749 Phosphoglycerate kinase
1 1 SCOP 53763 UDP-N-acetylglucosamine 2-epimerase
1 1 SCOP 53775 Glutaminase/Asparaginase
1 1 SCOP 53791 Tetrapyrrole methylase
1 1 SCOP 53823 L-arabinose binding protein-like
1 1 SCOP 54193 L15e
1 1 SCOP 54232 GHMP Kinase, N-terminal domain
1 1 SCOP 54293 2Fe-2S ferredoxin-related
1 1 SCOP 54576 Ribosomal protein L31e
1 1 SCOP 54687 Ribosomal protein L10e
1 1 SCOP 54720 Fe,Mn superoxide dismutase (SOD), C-terminal domain
1 1 SCOP 54811 GMP synthetase C-terminal dimerisation domain
1 1 SCOP 54827 Enolase N-terminal domain-like
1 1 SCOP 54844 Ribosomal protein L22
1 1 SCOP 54894 Aspartate carbamoyltransferase, Regulatory-chain, N-terminal domain
1 1 SCOP 54920 Nucleoside diphosphate kinase, NDK
1 1 SCOP 55041 Molybdenum cofactor biosynthesis protein C, MoaC
1 1 SCOP 55069 Peptide methionine sulfoxide reductase
1 1 SCOP 55130 Ribosomal protein L30p/L7e
1 1 SCOP 55187 Threonyl-tRNA synthetase (ThrRS), second 'additional' domain
1 1 SCOP 55209 Enolpyruvate transferase, EPT
1 1 SCOP 55262 GAD domain
1 1 SCOP 55272 DNA repair protein MutS, domain I
1 1 SCOP 55283 Ribosomal protein L5
1 1 SCOP 55299 YjgF/L-PSP
1 1 SCOP 55316 L30e/L7ae ribosomal proteins
1 1 SCOP 55348 GAPDH-like
1 1 SCOP 55822 YrdC-like
1 1 SCOP 55910 Ribosome anti-association factor eIF6 (aIF6)
1 1 SCOP 55932 Glutamine synthetase catalytic domain
1 1 SCOP 56004 Molybdenum cofactor-binding domain
1 1 SCOP 56043 PurM C-terminal domain-like
1 1 SCOP 56048 Ribosomal protein S8
1 1 SCOP 56081 Succinyl-CoA synthetase, beta-chain, N-terminal domain
1 1 SCOP 56096 Adenylation domain of NAD+-dependent DNA ligase
1 1 SCOP 56200 Methenyltetrahydromethanopterin cyclohydrolase
1 1 SCOP 56210 Nitrile hydratase alpha chain
1 1 SCOP 56261 (Glycosyl)asparaginase
1 1 SCOP 56328 Lactate & malate dehydrogenases, C-terminal domain
1 1 SCOP 56426 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain
1 1 SCOP 56525 Oxidoreductase molybdopterin-binding domain
1 1 SCOP 56543 Substrate-binding domain of HMG-CoA reductase
1 1 SCOP 56656 Inositol monophosphatase/fructose-1,6-bisphosphatase-like
1 1 SCOP 56713 Prokaryotic type I DNA topoisomerase
1 1 SCOP 56720 Type II DNA topoisomerase
1 1 SCOP 56727 DNA topoisomerase IV, alpha subunit
1 1 SCOP 56748 PriA-like
1 1 SCOP 56809 Ribosomal protein L1
1 1 SCOP 57836 Ribosomal protein L44e
1 1 SCOP 64006 Undecaprenyl diphosphate synthase
1 1 SCOP 64159 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain
1 1 SCOP 64162 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, catalytic domain
1 1 SCOP 64198 AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC
1 1 SCOP 64372 3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB
1 1 SCOP 64511 Phosphoserine phosphatase
1 1 SCOP 69565 Pyridoxal-dependent decarboxylase
1 1 SCOP 69573 Molybdenum cofactor biosynthesis protein MoeB
1 1 SCOP 69581 PepX catalytic domain-like
1 1 SCOP 69602 L-histidinol dehydrogenase HisD
1 1 SCOP 69746 Pseudouridine synthase II TruB
1 1 SCOP 69865 Argininosuccinate synthetase, C-terminal domain
1 1 SCOP 75041 SelR domain
1 1 SCOP 75292 YjeF C-terminal domain-like
1 1 SCOP 75297 N-acetyl-l-glutamate kinase
1 1 SCOP 75570 Archaeal IMP cyclohydrolase PurO
1 1 SCOP 75648 ABC transporter involved in vitamin B12 uptake, BtuC
1 1 SCOP 81642 Cytochrome b of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
1 1 SCOP 82275 Ssud-like monoxygenases
1 1 SCOP 82545 GckA/TtuD-like
1 1 SCOP 88741 Branched-chain alpha-keto acid dehydrogenase Pyr module
1 1 SCOP 88749 Pyruvate oxidase and decarboxylase PP module
1 1 SCOP 88766 Branched-chain alpha-keto acid dehydrogenase PP module
1 1 SCOP 89032 Cobalamin adenosyltransferase
1 1 SCOP 89125 Nop domain
1 1 SCOP 89332 DNA replication initiator (cdc21/cdc54) N-terminal domain
1 1 SCOP 89716 XPF/Rad1/Mus81 nuclease
1 1 SCOP 100888 Lesion bypass DNA polymerase (Y-family), catalytic domain
1 1 SCOP 100921 Heat shock protein 70kD (HSP70), peptide-binding domain
1 1 SCOP 101458 TENA/THI-4
1 1 SCOP 101905 GyrA/ParC C-terminal domain-like
1 1 SCOP 102216 Creatininase
1 1 SCOP 102463 Peptidyl-tRNA hydrolase II
1 1 SCOP 102575 NOL1/NOP2/sun
1 1 SCOP 102663 Phosphotransacetylase
1 1 SCOP 102706 NIF3 (NGG1p interacting factor 3)-like
1 1 SCOP 102769 ATP-dependent protease Lon (La), catalytic domain
1 1 SCOP 103026 Aminomethyltransferase folate-binding domain
1 1 SCOP 103264 Chorismate synthase, AroC
1 1 SCOP 103281 Lysine biosynthesis enzyme LysX ATP-binding domain
1 1 SCOP 103366 Hypothetical protein PH1602
1 1 SCOP 103492 Preprotein translocase SecY subunit
1 1 SCOP 110368 NeuB-like
1 1 SCOP 110384 Cobalamin-independent methionine synthase
1 1 SCOP 110513 IF2B-like
1 1 SCOP 110965 Chlorite dismutase-like
1 1 SCOP 111160 Glutamate-cysteine ligase family 2 (GCS2)
1 1 SCOP 117558 Type II thymidine kinase
1 1 SCOP 140372 Vng1086c-like
1 1 SCOP 140664 TTHA0068-like
1 1 SCOP 140970 Atu0492-like
1 1 SCOP 141735 HisI-like
1 1 SCOP 141755 PdxS-like
1 1 SCOP 142339 CofD-like
1 1 SCOP 142434 CinA-like
1 1 SCOP 142536 AF0625-like
1 1 SCOP 142701 RibD C-terminal domain-like
1 1 SCOP 142721 PyrH-like
1 1 SCOP 143082 BB1717-like
1 1 SCOP 143423 Transposase IS200-like
1 1 SCOP 143866 CorA soluble domain-like
1 1 SCOP 143906 Gamma-glutamyltranspeptidase-like
1 1 SCOP 143916 RNase Z-like
1 1 SCOP 143976 lvD/EDD N-terminal domain-like
1 1 SCOP 144011 CofE-like
1 1 SCOP 144028 Nqo4-like
1 1 SCOP 144031 Nq06-like
1 1 SCOP 158338 Rps19E-like
1 1 SCOP 158706 Achaeal helicase C-terminal domain
1 1 SCOP 159112 RNB domain-like
1 1 SCOP 159464 AF0587 domain-like
1 1 SCOP 159518 AF1056-like
1 1 SCOP 159523 AF0751-like
1 1 SCOP 159697 TRM1-like
1 1 SCOP 159720 mannose-1-phosphate guanylyl transferase
1 1 SCOP 159723 MM2497-like
1 1 SCOP 159756 O-acetyltransferase
1 1 SCOP 159765 Aminoglycoside 3-N-acetyltransferase-like
1 1 SCOP 160552 Caur0242-like
1 1 SCOP 160976 AF1531-like
1 1 SCOP 160984 Diacylglycerol kinase-like

The following families have one or more weak hits: