Family Assignments

Domains Proteins SCOP Link Families
37 35 SCOP 52686 ABC transporter ATPase domain-like
20 19 SCOP 69361 Cell wall binding repeat
12 9 SCOP 81268 Tandem AAA-ATPase domain
10 8 SCOP 81269 Extended AAA-ATPase domain
9 9 SCOP 161099 MetI-like
8 8 SCOP 51446 Amylase, catalytic domain
8 8 SCOP 52375 Class I aminoacyl-tRNA synthetases (RS), catalytic domain
7 7 SCOP 53823 L-arabinose binding protein-like
7 7 SCOP 53851 Phosphate binding protein-like
7 7 SCOP 55682 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
6 6 SCOP 52592 G proteins
6 6 SCOP 56802 Acetyl-CoA synthetase-like
5 5 SCOP 51570 Class I aldolase
5 5 SCOP 53272 Phosphoribosyltransferases (PRTases)
5 4 SCOP 56067 BC ATP-binding domain-like
4 4 SCOP 52318 Class I glutamine amidotransferases (GAT)
4 4 SCOP 52670 RecA protein-like (ATPase-domain)
4 4 SCOP 53384 AAT-like
4 4 SCOP 53402 Cystathionine synthase-like
4 4 SCOP 53687 Tryptophan synthase beta subunit-like PLP-dependent enzymes
4 4 SCOP 75648 ABC transporter involved in vitamin B12 uptake, BtuC
4 4 SCOP 88854 Protein kinases, catalytic subunit
3 3 SCOP 48558 L-aspartase/fumarase
3 3 SCOP 50282 Cold shock DNA-binding domain-like
3 3 SCOP 50448 Elongation factors
3 3 SCOP 51431 Aldo-keto reductases (NADP)
3 3 SCOP 51751 Tyrosine-dependent oxidoreductases
3 3 SCOP 51883 Aminoacid dehydrogenase-like, C-terminal domain
3 2 SCOP 52441 BC N-terminal domain-like
3 3 SCOP 52541 Nucleotide and nucleoside kinases
3 3 SCOP 52652 Nitrogenase iron protein-like
3 3 SCOP 52744 Subtilases
3 3 SCOP 53168 Purine and uridine phosphorylases
3 3 SCOP 53417 GABA-aminotransferase-like
3 3 SCOP 53721 ALDH-like
3 2 SCOP 54229 Ribonuclease PH domain 1-like
3 3 SCOP 54815 Prokaryotic type KH domain (KH-domain type II)
3 3 SCOP 55921 Creatinase/aminopeptidase
3 3 SCOP 55932 Glutamine synthetase catalytic domain
3 1 SCOP 55974 S-adenosylmethionine synthetase
2 2 SCOP 47918 C-terminal domain of alpha and beta subunits of F1 ATP synthase
2 2 SCOP 48222 N-acylglucosamine (NAG) epimerase
2 2 SCOP 50678 ValRS/IleRS/LeuRS editing domain
2 2 SCOP 50940 Sialidases (neuraminidases)
2 2 SCOP 51262 Glucose permease-like
2 2 SCOP 51381 Tryptophan biosynthesis enzymes
2 2 SCOP 51396 FMN-linked oxidoreductases
2 2 SCOP 51413 Inosine monophosphate dehydrogenase (IMPDH)
2 2 SCOP 51420 Alanine racemase-like, N-terminal domain
2 2 SCOP 51487 beta-glycanases
2 2 SCOP 51591 Class II FBP aldolase
2 2 SCOP 51800 Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
2 2 SCOP 51848 LDH N-terminal domain-like
2 2 SCOP 51868 6-phosphogluconate dehydrogenase-like, N-terminal domain
2 2 SCOP 52097 Clp protease, ClpP subunit
2 2 SCOP 52173 CheY-related
2 2 SCOP 52211 Succinyl-CoA synthetase domains
2 2 SCOP 52397 Adenylyltransferase
2 2 SCOP 52403 N-type ATP pyrophosphatases
2 2 SCOP 52419 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
2 2 SCOP 52778 CAT-like
2 2 SCOP 52923 Transketolase C-terminal domain-like
2 1 SCOP 53068 Actin/HSP70
2 1 SCOP 53080 Acetokinase-like
2 1 SCOP 53089 Glycerol kinase
2 2 SCOP 53099 Ribonuclease H
2 2 SCOP 53464 glucose-1-phosphate thymidylyltransferase
2 2 SCOP 53624 MurCDEF
2 2 SCOP 53707 Formate dehydrogenase/DMSO reductase, domains 1-3
2 1 SCOP 53785 Phosphofructokinase
2 2 SCOP 54212 Translational machinery components
2 2 SCOP 54232 GHMP Kinase, N-terminal domain
2 2 SCOP 54884 Ferredoxin domains from multidomain proteins
2 2 SCOP 55209 Enolpyruvate transferase, EPT
2 2 SCOP 55327 PurM N-terminal domain-like
2 2 SCOP 55348 GAPDH-like
2 2 SCOP 55368 Dihydrodipicolinate reductase-like
2 1 SCOP 55667 Ribonuclease PH domain 2-like
2 2 SCOP 55879 DNA gyrase/MutL, N-terminal domain
2 2 SCOP 56043 PurM C-terminal domain-like
2 2 SCOP 56236 Class II glutamine amidotransferases
2 2 SCOP 56323 ADC synthase
2 2 SCOP 56328 Lactate & malate dehydrogenases, C-terminal domain
2 2 SCOP 56350 Lambda integrase-like, catalytic core
2 2 SCOP 56720 Type II DNA topoisomerase
2 2 SCOP 63883 MoeA N-terminal region -like
2 2 SCOP 64006 Undecaprenyl diphosphate synthase
2 2 SCOP 69912 Clc chloride channel
2 2 SCOP 75218 SpoU-like RNA 2'-O ribose methyltransferase
2 2 SCOP 75621 Release factor
2 2 SCOP 81605 PP2C-like
2 2 SCOP 88724 Pyruvate oxidase and decarboxylase Pyr module
2 2 SCOP 88735 TK-like Pyr module
2 2 SCOP 88760 TK-like PP module
2 2 SCOP 88947 Sigma2 domain of RNA polymerase sigma factors
2 1 SCOP 89572 Biotin dependent carboxylase carboxyltransferase domain
2 2 SCOP 102079 Putative alpha-L-fucosidase, catalytic domain
2 2 SCOP 102317 NagD-like
2 2 SCOP 109613 DAK1
2 1 SCOP 110384 Cobalamin-independent methionine synthase
2 2 SCOP 142721 PyrH-like
2 2 SCOP 158600 MgsA/YrvN C-terminal domain-like
2 2 SCOP 159832 PBP transglycosylase domain-like
1 1 SCOP 46610 Fe,Mn superoxide dismutase (SOD), N-terminal domain
1 1 SCOP 46947 Ribosomal protein S13
1 1 SCOP 47064 Ribosomal protein S15
1 1 SCOP 47253 Ribonucleotide reductase-like
1 1 SCOP 47324 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
1 1 SCOP 47447 Signal peptide-binding domain
1 1 SCOP 47974 Ribosomal protein S7
1 1 SCOP 47980 Iron-dependent repressor protein, dimerization domain
1 1 SCOP 48025 N-terminal domain of DnaB helicase
1 1 SCOP 48109 Carbamoyl phosphate synthetase, large subunit connection domain
1 1 SCOP 48169 R1 subunit of ribonucleotide reductase, N-terminal domain
1 1 SCOP 48174 Cryptochrome/photolyase FAD-binding domain
1 1 SCOP 48180 Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain
1 1 SCOP 48184 Acetohydroxy acid isomeroreductase (ketol-acid reductoisomerase, KARI)
1 1 SCOP 48197 Glycerol-3-phosphate dehydrogenase
1 1 SCOP 48577 Isoprenyl diphosphate synthases
1 1 SCOP 48593 GroEL chaperone, ATPase domain
1 1 SCOP 49803 beta-Galactosidase/glucuronidase, N-terminal domain
1 1 SCOP 49995 beta-Galactosidase, domain 5
1 1 SCOP 50114 C-terminal domain of ribosomal protein L2
1 1 SCOP 50130 GroES
1 1 SCOP 50136 Alcohol dehydrogenase-like, N-terminal domain
1 1 SCOP 50194 Ribosomal protein L14
1 1 SCOP 50263 Single strand DNA-binding domain, SSB
1 1 SCOP 50325 Inorganic pyrophosphatase
1 1 SCOP 50444 L-fucose isomerase, C-terminal domain
1 1 SCOP 50461 Ribosomal protein L3
1 1 SCOP 50466 EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
1 1 SCOP 50495 Prokaryotic proteases
1 1 SCOP 50693 Pyruvoyl dependent aspartate decarboxylase, ADC
1 1 SCOP 50696 Formate dehydrogenase/DMSO reductase, C-terminal domain
1 1 SCOP 50892 Cyclophilin (peptidylprolyl isomerase)
1 1 SCOP 51168 Galactoside acetyltransferase-like
1 1 SCOP 51183 dTDP-sugar isomerase
1 1 SCOP 51191 Type I phosphomannose isomerase
1 1 SCOP 51284 dUTPase-like
1 1 SCOP 51352 Triosephosphate isomerase (TIM)
1 1 SCOP 51367 Histidine biosynthesis enzymes
1 1 SCOP 51372 D-ribulose-5-phosphate 3-epimerase
1 1 SCOP 51550 beta-N-acetylhexosaminidase catalytic domain
1 1 SCOP 51594 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase)
1 1 SCOP 51605 Enolase
1 1 SCOP 51622 Pyruvate kinase
1 1 SCOP 51629 Pyruvate phosphate dikinase, C-terminal domain
1 1 SCOP 51665 Xylose isomerase
1 1 SCOP 51714 tRNA-guanine transglycosylase
1 1 SCOP 51718 Dihydropteroate synthetase
1 1 SCOP 51727 Uroporphyrinogen decarboxylase, UROD
1 1 SCOP 51731 Methylenetetrahydrofolate reductase
1 1 SCOP 51736 Alcohol dehydrogenase-like, C-terminal domain
1 1 SCOP 51830 Formate/glycerate dehydrogenases, NAD-domain
1 1 SCOP 51900 CoA-binding domain
1 1 SCOP 51999 PFL-like
1 1 SCOP 52002 R1 subunit of ribonucleotide reductase, C-terminal domain
1 1 SCOP 52022 Carbamoyl phosphate synthetase, small subunit N-terminal domain
1 1 SCOP 52030 GroEL-like chaperone, apical domain
1 1 SCOP 52081 Ribosomal proteins L15p and L18e
1 1 SCOP 52103 Crotonase-like
1 1 SCOP 52142 Uracil-DNA glycosylase
1 1 SCOP 52162 Ribosomal protein L13
1 1 SCOP 52167 Ribosomal protein L4
1 1 SCOP 52256 N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
1 1 SCOP 52314 Ribosomal protein S2
1 1 SCOP 52471 C-terminal domain of the electron transfer flavoprotein alpha subunit
1 1 SCOP 52475 Pyruvate oxidase and decarboxylase, middle domain
1 1 SCOP 52491 Tubulin, GTPase domain
1 1 SCOP 52513 NagB-like
1 1 SCOP 52566 Shikimate kinase (AroK)
1 1 SCOP 52584 Phosphoribulokinase/pantothenate kinase
1 1 SCOP 52944 ATP synthase (F1-ATPase), gamma subunit
1 1 SCOP 52973 ITPase (Ham1)
1 1 SCOP 53045 5' to 3' exonuclease catalytic domain
1 1 SCOP 53118 DnaQ-like 3'-5' exonuclease
1 1 SCOP 53138 Ribosomal protein L18 and S11
1 1 SCOP 53179 Peptidyl-tRNA hydrolase-like
1 1 SCOP 53219 MogA-like
1 1 SCOP 53224 Aminoacid dehydrogenases
1 1 SCOP 53240 Malic enzyme N-domain
1 1 SCOP 53255 Cofactor-dependent phosphoglycerate mutase
1 1 SCOP 53296 Phosphoribosylpyrophosphate synthetase-like
1 1 SCOP 53329 Formyltransferase
1 1 SCOP 53461 UDP-glucose pyrophosphorylase
1 1 SCOP 53496 Prolyl oligopeptidase, C-terminal domain
1 1 SCOP 53598 Dihydrofolate reductases
1 1 SCOP 53614 Ribokinase-like
1 1 SCOP 53629 Folylpolyglutamate synthetase
1 1 SCOP 53660 Dimeric isocitrate & isopropylmalate dehydrogenases
1 1 SCOP 53672 Aspartate/ornithine carbamoyltransferase
1 1 SCOP 53698 double-SIS domain
1 1 SCOP 53701 Phosphoglucose isomerase, PGI
1 1 SCOP 53733 Aconitase iron-sulfur domain
1 1 SCOP 53744 L-fucose isomerase, N-terminal and second domains
1 1 SCOP 53749 Phosphoglycerate kinase
1 1 SCOP 53760 Peptidoglycan biosynthesis glycosyltransferase MurG
1 1 SCOP 53766 Oligosaccharide phosphorylase
1 1 SCOP 53775 Glutaminase/Asparaginase
1 1 SCOP 53796 PEP carboxykinase C-terminal domain
1 1 SCOP 53811 TroA-like
1 1 SCOP 54002 Papain-like
1 1 SCOP 54224 DNA gyrase/MutL, second domain
1 1 SCOP 54369 Glutamine synthetase, N-terminal domain
1 1 SCOP 54571 Ribosomal protein S19
1 1 SCOP 54632 CBS-domain pair
1 1 SCOP 54720 Fe,Mn superoxide dismutase (SOD), C-terminal domain
1 1 SCOP 54748 Ribosomal L11/L12e N-terminal domain
1 1 SCOP 54811 GMP synthetase C-terminal dimerisation domain
1 1 SCOP 54822 Ribosomal protein S3 C-terminal domain
1 1 SCOP 54827 Enolase N-terminal domain-like
1 1 SCOP 54844 Ribosomal protein L22
1 1 SCOP 54920 Nucleoside diphosphate kinase, NDK
1 1 SCOP 54981 EF-G/eEF-2 domains III and V
1 1 SCOP 55000 Ribosomal protein S10
1 1 SCOP 55041 Molybdenum cofactor biosynthesis protein C, MoaC
1 1 SCOP 55069 Peptide methionine sulfoxide reductase
1 1 SCOP 55121 Pseudouridine synthase I TruA
1 1 SCOP 55178 Ribosomal protein S4
1 1 SCOP 55187 Threonyl-tRNA synthetase (ThrRS), second 'additional' domain
1 1 SCOP 55195 Ribosome recycling factor, RRF
1 1 SCOP 55201 Translation initiation factor IF3, C-terminal domain
1 1 SCOP 55283 Ribosomal protein L5
1 1 SCOP 55308 Tubulin, C-terminal domain
1 1 SCOP 55376 Glucose 6-phosphate dehydrogenase-like
1 1 SCOP 55470 NADH oxidase/flavin reductase
1 1 SCOP 55502 Neutral endopeptidase (neprilysin)
1 1 SCOP 55621 GTP cyclohydrolase I
1 1 SCOP 55822 YrdC-like
1 1 SCOP 55827 YbaK/ProRS associated domain
1 1 SCOP 55832 Thymidylate synthase/dCMP hydroxymethylase
1 1 SCOP 56038 B3/B4 domain of PheRS, PheT
1 1 SCOP 56048 Ribosomal protein S8
1 1 SCOP 56054 Ribosomal protein L6
1 1 SCOP 56060 ATP-binding domain of peptide synthetases
1 1 SCOP 56081 Succinyl-CoA synthetase, beta-chain, N-terminal domain
1 1 SCOP 56085 Pyruvate phosphate dikinase, N-terminal domain
1 1 SCOP 56096 Adenylation domain of NAD+-dependent DNA ligase
1 1 SCOP 56105 SAICAR synthase
1 1 SCOP 56421 Peptide deformylase
1 1 SCOP 56530 FAH
1 1 SCOP 56554 Insert subdomain of RNA polymerase alpha subunit
1 1 SCOP 56673 DNA polymerase I
1 1 SCOP 56713 Prokaryotic type I DNA topoisomerase
1 1 SCOP 56732 DNA primase DnaG catalytic core
1 1 SCOP 56753 D-aminoacid aminotransferase-like PLP-dependent enzymes
1 1 SCOP 56797 Dehydroquinate synthase, DHQS
1 1 SCOP 56809 Ribosomal protein L1
1 1 SCOP 56895 Aquaporin-like
1 1 SCOP 63412 MPP-like
1 1 SCOP 63971 Inosicase
1 1 SCOP 63976 Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC)
1 1 SCOP 63984 Sir2 family of transcriptional regulators
1 1 SCOP 64117 tRNA(1-methyladenosine) methyltransferase-like
1 1 SCOP 64198 AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC
1 1 SCOP 64294 Autoinducer-2 production protein LuxS
1 1 SCOP 64485 RNA-polymerase beta
1 1 SCOP 64490 RNA-polymerase beta-prime
1 1 SCOP 64511 Phosphoserine phosphatase
1 1 SCOP 68901 Cytidylytransferase
1 1 SCOP 68924 PEP carboxykinase N-terminal domain
1 1 SCOP 69066 RNase III catalytic domain-like
1 1 SCOP 69427 UDP-galactopyranose mutase, N-terminal domain
1 1 SCOP 69706 Transcription factor NusA, N-terminal domain
1 1 SCOP 69746 Pseudouridine synthase II TruB
1 1 SCOP 69766 IpsF-like
1 1 SCOP 69865 Argininosuccinate synthetase, C-terminal domain
1 1 SCOP 74732 Ribosomal protein L20
1 1 SCOP 74756 3-Methyladenine DNA glycosylase I (Tag)
1 1 SCOP 74983 Small protein B (SmpB)
1 1 SCOP 75041 SelR domain
1 1 SCOP 75073 Hydantoinase (dihydropyrimidinase), catalytic domain
1 1 SCOP 75305 Amidase signature (AS) enzymes
1 1 SCOP 75459 Pseudouridine synthase RsuA/RluD
1 1 SCOP 75626 YebC-like
1 1 SCOP 81768 Pre-protein crosslinking domain of SecA
1 1 SCOP 81887 Helical scaffold and wing domains of SecA
1 1 SCOP 82052 Obg GTP-binding protein N-terminal domain
1 1 SCOP 82261 N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain
1 1 SCOP 82267 TatD Mg-dependent DNase-like
1 1 SCOP 82583 G domain-linked domain
1 1 SCOP 82680 N-utilization substance G protein NusG, N-terminal domain
1 1 SCOP 82785 Ohr/OsmC resistance proteins
1 1 SCOP 88682 Alanine racemase
1 1 SCOP 88683 Eukaryotic ODC-like
1 1 SCOP 88741 Branched-chain alpha-keto acid dehydrogenase Pyr module
1 1 SCOP 88749 Pyruvate oxidase and decarboxylase PP module
1 1 SCOP 88766 Branched-chain alpha-keto acid dehydrogenase PP module
1 1 SCOP 88784 rRNA adenine dimethylase-like
1 1 SCOP 89279 Hypothetical protein HI1317
1 1 SCOP 89494 HMGL-like
1 1 SCOP 89503 Ketopantoate hydroxymethyltransferase PanB
1 1 SCOP 89624 Ribose/Galactose isomerase RpiB/AlsB
1 1 SCOP 89629 tRNA(m1G37)-methyltransferase TrmD
1 1 SCOP 89724 Macro domain
1 1 SCOP 89800 Deoxycytidylate deaminase-like
1 1 SCOP 100888 Lesion bypass DNA polymerase (Y-family), catalytic domain
1 1 SCOP 100921 Heat shock protein 70kD (HSP70), peptide-binding domain
1 1 SCOP 100948 Isochorismatase-like hydrolases
1 1 SCOP 101340 HD domain
1 1 SCOP 101354 Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
1 1 SCOP 101474 DhaL-like
1 1 SCOP 101884 Glycosyl hydrolases family 32 N-terminal domain
1 1 SCOP 101905 GyrA/ParC C-terminal domain-like
1 1 SCOP 102406 MoCo carrier protein-like
1 1 SCOP 102646 CoaB-like
1 1 SCOP 102663 Phosphotransacetylase
1 1 SCOP 102706 NIF3 (NGG1p interacting factor 3)-like
1 1 SCOP 102772 YigZ N-terminal domain-like
1 1 SCOP 102928 NifU/IscU domain
1 1 SCOP 102945 RelA/SpoT domain
1 1 SCOP 103264 Chorismate synthase, AroC
1 1 SCOP 103474 Glycerol-3-phosphate transporter
1 1 SCOP 103502 Respiratory nitrate reductase 1 gamma chain
1 1 SCOP 110309 Serine acetyltransferase
1 1 SCOP 110388 MoCo biosynthesis proteins
1 1 SCOP 110396 CutC-like
1 1 SCOP 110636 ROK
1 1 SCOP 111160 Glutamate-cysteine ligase family 2 (GCS2)
1 1 SCOP 111305 Recombination protein RecR
1 1 SCOP 111332 NAD kinase-like
1 1 SCOP 117362 NanE-like
1 1 SCOP 117372 YicI catalytic domain-like
1 1 SCOP 117783 YbjQ-like
1 1 SCOP 117888 Ribosomal protein L16p
1 1 SCOP 140991 FtsH protease domain-like
1 1 SCOP 141245 Ribosomal protein L19
1 1 SCOP 141755 PdxS-like
1 1 SCOP 141840 Class-II DAHP synthetase
1 1 SCOP 142020 Nqo1 FMN-binding domain-like
1 1 SCOP 142200 YkgG-like
1 1 SCOP 142339 CofD-like
1 1 SCOP 143473 UTRA domain
1 1 SCOP 143549 Serine dehydratase beta chain-like
1 1 SCOP 143642 LplA-like
1 1 SCOP 143812 GatB/GatE catalytic domain-like
1 1 SCOP 143921 Pce catalytic domain-like
1 1 SCOP 143976 lvD/EDD N-terminal domain-like
1 1 SCOP 144028 Nqo4-like
1 1 SCOP 144031 Nq06-like
1 1 SCOP 159660 Cgl1923-like
1 1 SCOP 159714 Dhaf3308-like
1 1 SCOP 159720 mannose-1-phosphate guanylyl transferase
1 1 SCOP 159756 O-acetyltransferase
1 1 SCOP 159889 YdhG-like
1 1 SCOP 160370 Ribosomal protein L10-like
1 1 SCOP 160380 SP0830-like
1 1 SCOP 161071 SNF-like

The following families have one or more weak hits: