Family Assignments

Domains Proteins SCOP Link Families
27 27 SCOP 52686 ABC transporter ATPase domain-like
13 10 SCOP 81269 Extended AAA-ATPase domain
9 9 SCOP 51751 Tyrosine-dependent oxidoreductases
9 9 SCOP 53402 Cystathionine synthase-like
8 8 SCOP 52318 Class I glutamine amidotransferases (GAT)
8 8 SCOP 52375 Class I aminoacyl-tRNA synthetases (RS), catalytic domain
8 8 SCOP 52652 Nitrogenase iron protein-like
7 7 SCOP 53384 AAT-like
7 7 SCOP 55682 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
7 7 SCOP 56802 Acetyl-CoA synthetase-like
6 6 SCOP 53687 Tryptophan synthase beta subunit-like PLP-dependent enzymes
6 5 SCOP 81268 Tandem AAA-ATPase domain
5 5 SCOP 51396 FMN-linked oxidoreductases
5 5 SCOP 52403 N-type ATP pyrophosphatases
5 5 SCOP 52592 G proteins
4 4 SCOP 48596 Group II chaperonin (CCT, TRIC), ATPase domain
4 4 SCOP 52034 Group II chaperonin (CCT, TRIC), apical domain
4 4 SCOP 52211 Succinyl-CoA synthetase domains
4 3 SCOP 52670 RecA protein-like (ATPase-domain)
4 2 SCOP 53068 Actin/HSP70
4 4 SCOP 53417 GABA-aminotransferase-like
4 4 SCOP 53816 Nitrogenase iron-molybdenum protein
4 4 SCOP 53851 Phosphate binding protein-like
4 2 SCOP 55113 Formylmethanofuran:tetrahydromethanopterin formyltransferase
4 3 SCOP 56067 BC ATP-binding domain-like
4 4 SCOP 58105 Methyl-accepting chemotaxis protein (MCP) signaling domain
3 3 SCOP 50448 Elongation factors
3 3 SCOP 51570 Class I aldolase
3 3 SCOP 51830 Formate/glycerate dehydrogenases, NAD-domain
3 3 SCOP 51868 6-phosphogluconate dehydrogenase-like, N-terminal domain
3 2 SCOP 52441 BC N-terminal domain-like
3 3 SCOP 53707 Formate dehydrogenase/DMSO reductase, domains 1-3
3 3 SCOP 53791 Tetrapyrrole methylase
3 3 SCOP 55348 GAPDH-like
3 3 SCOP 56043 PurM C-terminal domain-like
3 3 SCOP 56236 Class II glutamine amidotransferases
3 3 SCOP 88854 Protein kinases, catalytic subunit
2 2 SCOP 46610 Fe,Mn superoxide dismutase (SOD), N-terminal domain
2 2 SCOP 47241 Ferritin
2 1 SCOP 47965 Transcription factor IIB (TFIIB), core domain
2 2 SCOP 48082 Methyl-coenzyme M reductase alpha and beta chain C-terminal domain
2 2 SCOP 48558 L-aspartase/fumarase
2 2 SCOP 50466 EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
2 2 SCOP 50892 Cyclophilin (peptidylprolyl isomerase)
2 2 SCOP 51367 Histidine biosynthesis enzymes
2 2 SCOP 51381 Tryptophan biosynthesis enzymes
2 2 SCOP 51420 Alanine racemase-like, N-terminal domain
2 2 SCOP 51691 NadC C-terminal domain-like
2 2 SCOP 51800 Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
2 2 SCOP 51883 Aminoacid dehydrogenase-like, C-terminal domain
2 2 SCOP 52017 LeuD-like
2 2 SCOP 52419 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
2 2 SCOP 52491 Tubulin, GTPase domain
2 2 SCOP 52739 Methylesterase CheB, C-terminal domain
2 2 SCOP 53660 Dimeric isocitrate & isopropylmalate dehydrogenases
2 2 SCOP 53733 Aconitase iron-sulfur domain
2 2 SCOP 53749 Phosphoglycerate kinase
2 2 SCOP 54224 DNA gyrase/MutL, second domain
2 2 SCOP 54720 Fe,Mn superoxide dismutase (SOD), C-terminal domain
2 2 SCOP 54914 Prokaryotic signal transducing protein
2 2 SCOP 55069 Peptide methionine sulfoxide reductase
2 2 SCOP 55094 Methyl-coenzyme M reductase alpha and beta chain N-terminal domain
2 2 SCOP 55308 Tubulin, C-terminal domain
2 2 SCOP 55327 PurM N-terminal domain-like
2 2 SCOP 55879 DNA gyrase/MutL, N-terminal domain
2 2 SCOP 55921 Creatinase/aminopeptidase
2 2 SCOP 55932 Glutamine synthetase catalytic domain
2 2 SCOP 56220 DNase I-like
2 2 SCOP 56251 Proteasome subunits
2 2 SCOP 56291 ROO N-terminal domain-like
2 2 SCOP 56328 Lactate & malate dehydrogenases, C-terminal domain
2 2 SCOP 56656 Inositol monophosphatase/fructose-1,6-bisphosphatase-like
2 2 SCOP 56673 DNA polymerase I
2 2 SCOP 63883 MoeA N-terminal region -like
2 2 SCOP 64089 BadF/BadG/BcrA/BcrD-like
2 2 SCOP 64485 RNA-polymerase beta
2 2 SCOP 64490 RNA-polymerase beta-prime
2 1 SCOP 74753 Catalase-peroxidase KatG
2 2 SCOP 82852 Acetyl-CoA synthase
2 2 SCOP 100921 Heat shock protein 70kD (HSP70), peptide-binding domain
2 2 SCOP 101340 HD domain
2 2 SCOP 102769 ATP-dependent protease Lon (La), catalytic domain
2 2 SCOP 110513 IF2B-like
2 2 SCOP 111353 Ammonium transporter
2 2 SCOP 142701 RibD C-terminal domain-like
2 2 SCOP 142721 PyrH-like
2 2 SCOP 143812 GatB/GatE catalytic domain-like
2 1 SCOP 143860 Polyphosphate kinase C-terminal domain
2 2 SCOP 144011 CofE-like
2 2 SCOP 159704 SepSecS-like
1 1 SCOP 47447 Signal peptide-binding domain
1 1 SCOP 47808 5' to 3' exonuclease, C-terminal subdomain
1 1 SCOP 47974 Ribosomal protein S7
1 1 SCOP 48141 Ribosomal protein L19 (L19e)
1 1 SCOP 48184 Acetohydroxy acid isomeroreductase (ketol-acid reductoisomerase, KARI)
1 1 SCOP 48335 DNA repair protein MutS, domain III
1 1 SCOP 48577 Isoprenyl diphosphate synthases
1 1 SCOP 48593 GroEL chaperone, ATPase domain
1 1 SCOP 49368 Superoxide reductase-like
1 1 SCOP 50114 C-terminal domain of ribosomal protein L2
1 1 SCOP 50194 Ribosomal protein L14
1 1 SCOP 50277 Myf domain
1 1 SCOP 50282 Cold shock DNA-binding domain-like
1 1 SCOP 50461 Ribosomal protein L3
1 1 SCOP 50678 ValRS/IleRS/LeuRS editing domain
1 1 SCOP 51183 dTDP-sugar isomerase
1 1 SCOP 51247 BC C-terminal domain-like
1 1 SCOP 51352 Triosephosphate isomerase (TIM)
1 1 SCOP 51375 Decarboxylase
1 1 SCOP 51392 Thiamin phosphate synthase
1 1 SCOP 51413 Inosine monophosphate dehydrogenase (IMPDH)
1 1 SCOP 51594 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase)
1 1 SCOP 51605 Enolase
1 1 SCOP 51650 RuBisCo, large subunit, C-terminal domain
1 1 SCOP 51659 Endonuclease IV
1 1 SCOP 51687 F420 dependent oxidoreductases
1 1 SCOP 51714 tRNA-guanine transglycosylase
1 1 SCOP 51718 Dihydropteroate synthetase
1 1 SCOP 51900 CoA-binding domain
1 1 SCOP 51934 Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain
1 1 SCOP 52030 GroEL-like chaperone, apical domain
1 1 SCOP 52043 Ribosomal protein L32e
1 1 SCOP 52081 Ribosomal proteins L15p and L18e
1 1 SCOP 52162 Ribosomal protein L13
1 1 SCOP 52167 Ribosomal protein L4
1 1 SCOP 52173 CheY-related
1 1 SCOP 52256 N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
1 1 SCOP 52297 L-alanine dehydrogenase-like
1 1 SCOP 52300 S-adenosylhomocystein hydrolase
1 1 SCOP 52314 Ribosomal protein S2
1 1 SCOP 52325 DJ-1/PfpI
1 1 SCOP 52397 Adenylyltransferase
1 1 SCOP 52468 Deoxyhypusine synthase, DHS
1 1 SCOP 52475 Pyruvate oxidase and decarboxylase, middle domain
1 1 SCOP 52484 Transhydrogenase domain III (dIII)
1 1 SCOP 52508 Homo-oligomeric flavin-containing Cys decarboxylases, HFCD
1 1 SCOP 52541 Nucleotide and nucleoside kinases
1 1 SCOP 52769 Arginase-like amidino hydrolases
1 1 SCOP 52789 Low-molecular-weight phosphotyrosine protein phosphatases
1 1 SCOP 52955 Anticodon-binding domain of Class II aaRS
1 1 SCOP 52973 ITPase (Ham1)
1 1 SCOP 53045 5' to 3' exonuclease catalytic domain
1 1 SCOP 53057 beta-carbonic anhydrase, cab
1 1 SCOP 53099 Ribonuclease H
1 1 SCOP 53134 RuvC resolvase
1 1 SCOP 53138 Ribosomal protein L18 and S11
1 1 SCOP 53168 Purine and uridine phosphorylases
1 1 SCOP 53204 Bacterial dinuclear zinc exopeptidases
1 1 SCOP 53214 LigB-like
1 1 SCOP 53219 MogA-like
1 1 SCOP 53255 Cofactor-dependent phosphoglycerate mutase
1 1 SCOP 53272 Phosphoribosyltransferases (PRTases)
1 1 SCOP 53296 Phosphoribosylpyrophosphate synthetase-like
1 1 SCOP 53329 Formyltransferase
1 1 SCOP 53342 Fibrillarin homologue
1 1 SCOP 53354 Protein-L-isoaspartyl O-methyltransferase
1 1 SCOP 53444 Ornithine decarboxylase major domain
1 1 SCOP 53464 glucose-1-phosphate thymidylyltransferase
1 1 SCOP 53620 Thiamin biosynthesis kinases
1 1 SCOP 53672 Aspartate/ornithine carbamoyltransferase
1 1 SCOP 53698 double-SIS domain
1 1 SCOP 53721 ALDH-like
1 1 SCOP 53739 Phosphoglucomutase, first 3 domains
1 1 SCOP 53775 Glutaminase/Asparaginase
1 1 SCOP 53785 Phosphofructokinase
1 1 SCOP 54193 L15e
1 1 SCOP 54212 Translational machinery components
1 1 SCOP 54535 FKBP immunophilin/proline isomerase
1 1 SCOP 54687 Ribosomal protein L10e
1 1 SCOP 54811 GMP synthetase C-terminal dimerisation domain
1 1 SCOP 54827 Enolase N-terminal domain-like
1 1 SCOP 54844 Ribosomal protein L22
1 1 SCOP 54894 Aspartate carbamoyltransferase, Regulatory-chain, N-terminal domain
1 1 SCOP 54920 Nucleoside diphosphate kinase, NDK
1 1 SCOP 54967 Ribulose 1,5-bisphosphate carboxylase-oxygenase
1 1 SCOP 55041 Molybdenum cofactor biosynthesis protein C, MoaC
1 1 SCOP 55089 Methyl-coenzyme M reductase gamma chain
1 1 SCOP 55121 Pseudouridine synthase I TruA
1 1 SCOP 55130 Ribosomal protein L30p/L7e
1 1 SCOP 55209 Enolpyruvate transferase, EPT
1 1 SCOP 55262 GAD domain
1 1 SCOP 55272 DNA repair protein MutS, domain I
1 1 SCOP 55283 Ribosomal protein L5
1 1 SCOP 55316 L30e/L7ae ribosomal proteins
1 1 SCOP 55482 N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1
1 1 SCOP 55505 Neurolysin-like
1 1 SCOP 55817 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain
1 1 SCOP 55822 YrdC-like
1 1 SCOP 55884 Histidine kinase
1 1 SCOP 55910 Ribosome anti-association factor eIF6 (aIF6)
1 1 SCOP 56048 Ribosomal protein S8
1 1 SCOP 56105 SAICAR synthase
1 1 SCOP 56200 Methenyltetrahydromethanopterin cyclohydrolase
1 1 SCOP 56323 ADC synthase
1 1 SCOP 56426 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain
1 1 SCOP 56543 Substrate-binding domain of HMG-CoA reductase
1 1 SCOP 56713 Prokaryotic type I DNA topoisomerase
1 1 SCOP 56720 Type II DNA topoisomerase
1 1 SCOP 56727 DNA topoisomerase IV, alpha subunit
1 1 SCOP 56748 PriA-like
1 1 SCOP 56753 D-aminoacid aminotransferase-like PLP-dependent enzymes
1 1 SCOP 56809 Ribosomal protein L1
1 1 SCOP 56822 Hybrid cluster protein (prismane protein)
1 1 SCOP 56895 Aquaporin-like
1 1 SCOP 57836 Ribosomal protein L44e
1 1 SCOP 63966 Precorrin-8X methylmutase CbiC/CobH
1 1 SCOP 63971 Inosicase
1 1 SCOP 64006 Undecaprenyl diphosphate synthase
1 1 SCOP 64147 ADP-specific Phosphofructokinase/Glucokinase
1 1 SCOP 64168 SurE-like
1 1 SCOP 64183 Manganese-dependent inorganic pyrophosphatase (family II)
1 1 SCOP 64198 AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC
1 1 SCOP 64372 3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB
1 1 SCOP 64514 Carbon monoxide dehydrogenase
1 1 SCOP 69026 Hypothetical protein MTH865
1 1 SCOP 69599 mono-SIS domain
1 1 SCOP 69602 L-histidinol dehydrogenase HisD
1 1 SCOP 69746 Pseudouridine synthase II TruB
1 1 SCOP 69865 Argininosuccinate synthetase, C-terminal domain
1 1 SCOP 69892 Iron-containing alcohol dehydrogenase
1 1 SCOP 69912 Clc chloride channel
1 1 SCOP 75041 SelR domain
1 1 SCOP 75073 Hydantoinase (dihydropyrimidinase), catalytic domain
1 1 SCOP 75176 D-ribose-5-phosphate isomerase (RpiA), catalytic domain
1 1 SCOP 75297 N-acetyl-l-glutamate kinase
1 1 SCOP 75305 Amidase signature (AS) enzymes
1 1 SCOP 75648 ABC transporter involved in vitamin B12 uptake, BtuC
1 1 SCOP 81605 PP2C-like
1 1 SCOP 81656 Meta-cation ATPase, catalytic domain P
1 1 SCOP 81659 Metal cation-transporting ATPase, ATP-binding domain N
1 1 SCOP 82258 SAH/MTA deaminase-like
1 1 SCOP 82371 YbeA-like
1 1 SCOP 88683 Eukaryotic ODC-like
1 1 SCOP 88724 Pyruvate oxidase and decarboxylase Pyr module
1 1 SCOP 88749 Pyruvate oxidase and decarboxylase PP module
1 1 SCOP 88788 N6 adenine-specific DNA methylase, DAM
1 1 SCOP 89125 Nop domain
1 1 SCOP 89332 DNA replication initiator (cdc21/cdc54) N-terminal domain
1 1 SCOP 89409 TM1287-like
1 1 SCOP 89494 HMGL-like
1 1 SCOP 89590 NADPH-dependent FMN reductase
1 1 SCOP 89716 XPF/Rad1/Mus81 nuclease
1 1 SCOP 89800 Deoxycytidylate deaminase-like
1 1 SCOP 89863 PhzC/PhzF-like
1 1 SCOP 100888 Lesion bypass DNA polymerase (Y-family), catalytic domain
1 1 SCOP 100948 Isochorismatase-like hydrolases
1 1 SCOP 101899 NHL repeat
1 1 SCOP 101905 GyrA/ParC C-terminal domain-like
1 1 SCOP 101984 Pirin-like
1 1 SCOP 102199 Putative cyclase
1 1 SCOP 102325 F420-dependent methylenetetrahydromethanopterin dehydrogenase (MTD)
1 1 SCOP 102463 Peptidyl-tRNA hydrolase II
1 1 SCOP 102713 JAB1/MPN domain
1 1 SCOP 102928 NifU/IscU domain
1 1 SCOP 103264 Chorismate synthase, AroC
1 1 SCOP 103366 Hypothetical protein PH1602
1 1 SCOP 103492 Preprotein translocase SecY subunit
1 1 SCOP 109725 Conserved carboxylase domain
1 1 SCOP 109729 Hypothetical protein AF0491, middle domain
1 1 SCOP 109756 PhoU-like
1 1 SCOP 110309 Serine acetyltransferase
1 1 SCOP 110436 Ornithine cyclodeaminase-like
1 1 SCOP 110616 MTH1675-like
1 1 SCOP 111155 Porphyromonas-type peptidylarginine deiminase
1 1 SCOP 111219 ArgJ-like
1 1 SCOP 111250 Sulfolobus fructose-1,6-bisphosphatase-like
1 1 SCOP 111284 Putative modulator of DNA gyrase, PmbA/TldD
1 1 SCOP 111322 AF1104-like
1 1 SCOP 111332 NAD kinase-like
1 1 SCOP 111343 CbiD-like
1 1 SCOP 117458 FumA C-terminal domain-like
1 1 SCOP 117795 Formaldehyde-activating enzyme, FAE
1 1 SCOP 117857 Alpha-acetolactate decarboxylase-like
1 1 SCOP 141368 UbiD middle domain-like
1 1 SCOP 141735 HisI-like
1 1 SCOP 141755 PdxS-like
1 1 SCOP 141819 PP1699/LP2961-like
1 1 SCOP 141979 AF0055-like
1 1 SCOP 142040 AF1403 C-terminal domain-like
1 1 SCOP 142093 ThiI-like
1 1 SCOP 142339 CofD-like
1 1 SCOP 142536 AF0625-like
1 1 SCOP 142606 N-6 DNA Methylase-like
1 1 SCOP 142755 NadA-like
1 1 SCOP 143448 AMMECR1-like
1 1 SCOP 143916 RNase Z-like
1 1 SCOP 143927 beta-CASP RNA-metabolising hydrolases
1 1 SCOP 143976 lvD/EDD N-terminal domain-like
1 1 SCOP 144028 Nqo4-like
1 1 SCOP 158338 Rps19E-like
1 1 SCOP 158706 Achaeal helicase C-terminal domain
1 1 SCOP 159154 CTP-dependent riboflavin kinase-like
1 1 SCOP 159164 MTH863-like
1 1 SCOP 159464 AF0587 domain-like
1 1 SCOP 159518 AF1056-like
1 1 SCOP 159523 AF0751-like
1 1 SCOP 159697 TRM1-like
1 1 SCOP 159723 MM2497-like
1 1 SCOP 159756 O-acetyltransferase
1 1 SCOP 159821 FdhD/NarQ
1 1 SCOP 160883 CheD-like
1 1 SCOP 160976 AF1531-like
1 1 SCOP 161099 MetI-like

The following families have one or more weak hits: