Family Assignments

Domains Proteins SCOP Link Families
42 41 SCOP 52686 ABC transporter ATPase domain-like
13 13 SCOP 53851 Phosphate binding protein-like
10 10 SCOP 51751 Tyrosine-dependent oxidoreductases
10 7 SCOP 81268 Tandem AAA-ATPase domain
9 9 SCOP 52375 Class I aminoacyl-tRNA synthetases (RS), catalytic domain
9 7 SCOP 81269 Extended AAA-ATPase domain
8 8 SCOP 53721 ALDH-like
8 5 SCOP 53902 Thiolase-related
8 8 SCOP 55682 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
7 7 SCOP 52592 G proteins
7 4 SCOP 89572 Biotin dependent carboxylase carboxyltransferase domain
6 6 SCOP 52652 Nitrogenase iron protein-like
6 6 SCOP 53384 AAT-like
6 6 SCOP 53417 GABA-aminotransferase-like
6 6 SCOP 56802 Acetyl-CoA synthetase-like
5 5 SCOP 51396 FMN-linked oxidoreductases
5 5 SCOP 51883 Aminoacid dehydrogenase-like, C-terminal domain
5 5 SCOP 53272 Phosphoribosyltransferases (PRTases)
5 5 SCOP 53402 Cystathionine synthase-like
5 5 SCOP 161099 MetI-like
4 4 SCOP 51431 Aldo-keto reductases (NADP)
4 4 SCOP 51446 Amylase, catalytic domain
4 4 SCOP 52103 Crotonase-like
4 4 SCOP 52318 Class I glutamine amidotransferases (GAT)
4 4 SCOP 52541 Nucleotide and nucleoside kinases
4 4 SCOP 52670 RecA protein-like (ATPase-domain)
4 2 SCOP 53068 Actin/HSP70
4 3 SCOP 54815 Prokaryotic type KH domain (KH-domain type II)
4 4 SCOP 55921 Creatinase/aminopeptidase
4 3 SCOP 56067 BC ATP-binding domain-like
3 3 SCOP 47204 Medium chain acyl-CoA dehydrogenase-like, C-terminal domain
3 3 SCOP 48558 L-aspartase/fumarase
3 3 SCOP 50282 Cold shock DNA-binding domain-like
3 3 SCOP 50448 Elongation factors
3 3 SCOP 52211 Succinyl-CoA synthetase domains
3 3 SCOP 52403 N-type ATP pyrophosphatases
3 2 SCOP 52441 BC N-terminal domain-like
3 3 SCOP 52778 CAT-like
3 3 SCOP 53168 Purine and uridine phosphorylases
3 3 SCOP 53687 Tryptophan synthase beta subunit-like PLP-dependent enzymes
3 2 SCOP 54229 Ribonuclease PH domain 1-like
3 3 SCOP 55209 Enolpyruvate transferase, EPT
3 3 SCOP 55327 PurM N-terminal domain-like
3 3 SCOP 55348 GAPDH-like
3 1 SCOP 55974 S-adenosylmethionine synthetase
3 3 SCOP 56602 beta-Lactamase/D-ala carboxypeptidase
3 3 SCOP 56646 Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains
3 3 SCOP 75648 ABC transporter involved in vitamin B12 uptake, BtuC
3 3 SCOP 88854 Protein kinases, catalytic subunit
3 3 SCOP 142721 PyrH-like
2 2 SCOP 47253 Ribonucleotide reductase-like
2 2 SCOP 47918 C-terminal domain of alpha and beta subunits of F1 ATP synthase
2 2 SCOP 48265 Cytochrome P450
2 2 SCOP 48577 Isoprenyl diphosphate synthases
2 2 SCOP 48593 GroEL chaperone, ATPase domain
2 2 SCOP 50136 Alcohol dehydrogenase-like, N-terminal domain
2 2 SCOP 51284 dUTPase-like
2 2 SCOP 51367 Histidine biosynthesis enzymes
2 2 SCOP 51381 Tryptophan biosynthesis enzymes
2 2 SCOP 51413 Inosine monophosphate dehydrogenase (IMPDH)
2 2 SCOP 51570 Class I aldolase
2 2 SCOP 51691 NadC C-terminal domain-like
2 2 SCOP 51704 Methylmalonyl-CoA mutase, N-terminal (CoA-binding) domain
2 2 SCOP 51736 Alcohol dehydrogenase-like, C-terminal domain
2 2 SCOP 51800 Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
2 2 SCOP 51868 6-phosphogluconate dehydrogenase-like, N-terminal domain
2 2 SCOP 51943 FAD/NAD-linked reductases, N-terminal and central domains
2 2 SCOP 52030 GroEL-like chaperone, apical domain
2 2 SCOP 52097 Clp protease, ClpP subunit
2 2 SCOP 52173 CheY-related
2 2 SCOP 52397 Adenylyltransferase
2 2 SCOP 52419 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
2 2 SCOP 52744 Subtilases
2 1 SCOP 53080 Acetokinase-like
2 1 SCOP 53089 Glycerol kinase
2 2 SCOP 53099 Ribonuclease H
2 2 SCOP 53240 Malic enzyme N-domain
2 2 SCOP 53329 Formyltransferase
2 2 SCOP 53620 Thiamin biosynthesis kinases
2 2 SCOP 53624 MurCDEF
2 2 SCOP 53672 Aspartate/ornithine carbamoyltransferase
2 2 SCOP 53698 double-SIS domain
2 2 SCOP 53707 Formate dehydrogenase/DMSO reductase, domains 1-3
2 2 SCOP 53763 UDP-N-acetylglucosamine 2-epimerase
2 2 SCOP 53914 Chalcone synthase-like
2 2 SCOP 54212 Translational machinery components
2 1 SCOP 54981 EF-G/eEF-2 domains III and V
2 2 SCOP 55041 Molybdenum cofactor biosynthesis protein C, MoaC
2 2 SCOP 55368 Dihydrodipicolinate reductase-like
2 2 SCOP 55376 Glucose 6-phosphate dehydrogenase-like
2 2 SCOP 55425 FAD/NAD-linked reductases, dimerisation (C-terminal) domain
2 1 SCOP 55667 Ribonuclease PH domain 2-like
2 2 SCOP 55879 DNA gyrase/MutL, N-terminal domain
2 2 SCOP 55932 Glutamine synthetase catalytic domain
2 2 SCOP 56043 PurM C-terminal domain-like
2 2 SCOP 56236 Class II glutamine amidotransferases
2 2 SCOP 56350 Lambda integrase-like, catalytic core
2 2 SCOP 56530 FAH
2 2 SCOP 56635 Heme-dependent catalases
2 2 SCOP 56720 Type II DNA topoisomerase
2 2 SCOP 63984 Sir2 family of transcriptional regulators
2 2 SCOP 64006 Undecaprenyl diphosphate synthase
2 2 SCOP 74756 3-Methyladenine DNA glycosylase I (Tag)
2 2 SCOP 75218 SpoU-like RNA 2'-O ribose methyltransferase
2 2 SCOP 75621 Release factor
2 2 SCOP 88735 TK-like Pyr module
2 2 SCOP 88741 Branched-chain alpha-keto acid dehydrogenase Pyr module
2 2 SCOP 88760 TK-like PP module
2 2 SCOP 88766 Branched-chain alpha-keto acid dehydrogenase PP module
2 2 SCOP 88947 Sigma2 domain of RNA polymerase sigma factors
2 2 SCOP 100888 Lesion bypass DNA polymerase (Y-family), catalytic domain
2 2 SCOP 102589 LmbE-like
2 2 SCOP 102945 RelA/SpoT domain
2 2 SCOP 110388 MoCo biosynthesis proteins
2 1 SCOP 142678 Glycine dehydrogenase subunits (GDC-P)
2 2 SCOP 143082 BB1717-like
2 1 SCOP 143860 Polyphosphate kinase C-terminal domain
2 2 SCOP 159660 Cgl1923-like
1 1 SCOP 46463 Globins
1 1 SCOP 46947 Ribosomal protein S13
1 1 SCOP 47064 Ribosomal protein S15
1 1 SCOP 47324 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
1 1 SCOP 47447 Signal peptide-binding domain
1 1 SCOP 47974 Ribosomal protein S7
1 1 SCOP 47980 Iron-dependent repressor protein, dimerization domain
1 1 SCOP 48151 Endonuclease III
1 1 SCOP 48257 Citrate synthase
1 1 SCOP 48572 HAL/PAL-like
1 1 SCOP 50114 C-terminal domain of ribosomal protein L2
1 1 SCOP 50130 GroES
1 1 SCOP 50194 Ribosomal protein L14
1 1 SCOP 50263 Single strand DNA-binding domain, SSB
1 1 SCOP 50325 Inorganic pyrophosphatase
1 1 SCOP 50461 Ribosomal protein L3
1 1 SCOP 50466 EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
1 1 SCOP 50476 PNP-oxidase like
1 1 SCOP 50495 Prokaryotic proteases
1 1 SCOP 50678 ValRS/IleRS/LeuRS editing domain
1 1 SCOP 50892 Cyclophilin (peptidylprolyl isomerase)
1 1 SCOP 51171 GlmU C-terminal domain-like
1 1 SCOP 51231 Biotinyl/lipoyl-carrier proteins and domains
1 1 SCOP 51352 Triosephosphate isomerase (TIM)
1 1 SCOP 51372 D-ribulose-5-phosphate 3-epimerase
1 1 SCOP 51392 Thiamin phosphate synthase
1 1 SCOP 51420 Alanine racemase-like, N-terminal domain
1 1 SCOP 51591 Class II FBP aldolase
1 1 SCOP 51594 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase)
1 1 SCOP 51605 Enolase
1 1 SCOP 51622 Pyruvate kinase
1 1 SCOP 51629 Pyruvate phosphate dikinase, C-terminal domain
1 1 SCOP 51718 Dihydropteroate synthetase
1 1 SCOP 51727 Uroporphyrinogen decarboxylase, UROD
1 1 SCOP 51830 Formate/glycerate dehydrogenases, NAD-domain
1 1 SCOP 51848 LDH N-terminal domain-like
1 1 SCOP 51934 Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain
1 1 SCOP 52002 R1 subunit of ribonucleotide reductase, C-terminal domain
1 1 SCOP 52017 LeuD-like
1 1 SCOP 52022 Carbamoyl phosphate synthetase, small subunit N-terminal domain
1 1 SCOP 52081 Ribosomal proteins L15p and L18e
1 1 SCOP 52122 Lumazine synthase
1 1 SCOP 52142 Uracil-DNA glycosylase
1 1 SCOP 52152 FabD-like
1 1 SCOP 52162 Ribosomal protein L13
1 1 SCOP 52167 Ribosomal protein L4
1 1 SCOP 52235 Quinone reductase
1 1 SCOP 52243 Cobalamin (vitamin B12)-binding domain
1 1 SCOP 52256 N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
1 1 SCOP 52297 L-alanine dehydrogenase-like
1 1 SCOP 52314 Ribosomal protein S2
1 1 SCOP 52325 DJ-1/PfpI
1 1 SCOP 52410 PAPS reductase-like
1 1 SCOP 52432 ETFP subunits
1 1 SCOP 52471 C-terminal domain of the electron transfer flavoprotein alpha subunit
1 1 SCOP 52491 Tubulin, GTPase domain
1 1 SCOP 52584 Phosphoribulokinase/pantothenate kinase
1 1 SCOP 52769 Arginase-like amidino hydrolases
1 1 SCOP 52773 Histone deacetylase, HDAC
1 1 SCOP 52901 Glutathione peroxidase-like
1 1 SCOP 52923 Transketolase C-terminal domain-like
1 1 SCOP 52926 Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain
1 1 SCOP 52944 ATP synthase (F1-ATPase), gamma subunit
1 1 SCOP 52973 ITPase (Ham1)
1 1 SCOP 53045 5' to 3' exonuclease catalytic domain
1 1 SCOP 53118 DnaQ-like 3'-5' exonuclease
1 1 SCOP 53138 Ribosomal protein L18 and S11
1 1 SCOP 53179 Peptidyl-tRNA hydrolase-like
1 1 SCOP 53201 Leucine aminopeptidase, C-terminal domain
1 1 SCOP 53204 Bacterial dinuclear zinc exopeptidases
1 1 SCOP 53214 LigB-like
1 1 SCOP 53224 Aminoacid dehydrogenases
1 1 SCOP 53255 Cofactor-dependent phosphoglycerate mutase
1 1 SCOP 53296 Phosphoribosylpyrophosphate synthetase-like
1 1 SCOP 53461 UDP-glucose pyrophosphorylase
1 1 SCOP 53496 Prolyl oligopeptidase, C-terminal domain
1 1 SCOP 53509 Proline iminopeptidase-like
1 1 SCOP 53598 Dihydrofolate reductases
1 1 SCOP 53629 Folylpolyglutamate synthetase
1 1 SCOP 53733 Aconitase iron-sulfur domain
1 1 SCOP 53749 Phosphoglycerate kinase
1 1 SCOP 53760 Peptidoglycan biosynthesis glycosyltransferase MurG
1 1 SCOP 53785 Phosphofructokinase
1 1 SCOP 53791 Tetrapyrrole methylase
1 1 SCOP 53811 TroA-like
1 1 SCOP 54224 DNA gyrase/MutL, second domain
1 1 SCOP 54369 Glutamine synthetase, N-terminal domain
1 1 SCOP 54535 FKBP immunophilin/proline isomerase
1 1 SCOP 54571 Ribosomal protein S19
1 1 SCOP 54602 Extradiol dioxygenases
1 1 SCOP 54632 CBS-domain pair
1 1 SCOP 54714 Elongation factor Ts (EF-Ts), dimerisation domain
1 1 SCOP 54748 Ribosomal L11/L12e N-terminal domain
1 1 SCOP 54753 RecA protein, C-terminal domain
1 1 SCOP 54811 GMP synthetase C-terminal dimerisation domain
1 1 SCOP 54822 Ribosomal protein S3 C-terminal domain
1 1 SCOP 54827 Enolase N-terminal domain-like
1 1 SCOP 54844 Ribosomal protein L22
1 1 SCOP 54920 Nucleoside diphosphate kinase, NDK
1 1 SCOP 55000 Ribosomal protein S10
1 1 SCOP 55069 Peptide methionine sulfoxide reductase
1 1 SCOP 55121 Pseudouridine synthase I TruA
1 1 SCOP 55178 Ribosomal protein S4
1 1 SCOP 55187 Threonyl-tRNA synthetase (ThrRS), second 'additional' domain
1 1 SCOP 55195 Ribosome recycling factor, RRF
1 1 SCOP 55201 Translation initiation factor IF3, C-terminal domain
1 1 SCOP 55283 Ribosomal protein L5
1 1 SCOP 55308 Tubulin, C-terminal domain
1 1 SCOP 55502 Neutral endopeptidase (neprilysin)
1 1 SCOP 55621 GTP cyclohydrolase I
1 1 SCOP 55730 N-acetyl transferase, NAT
1 1 SCOP 55827 YbaK/ProRS associated domain
1 1 SCOP 55832 Thymidylate synthase/dCMP hydroxymethylase
1 1 SCOP 56038 B3/B4 domain of PheRS, PheT
1 1 SCOP 56048 Ribosomal protein S8
1 1 SCOP 56054 Ribosomal protein L6
1 1 SCOP 56060 ATP-binding domain of peptide synthetases
1 1 SCOP 56081 Succinyl-CoA synthetase, beta-chain, N-terminal domain
1 1 SCOP 56085 Pyruvate phosphate dikinase, N-terminal domain
1 1 SCOP 56096 Adenylation domain of NAD+-dependent DNA ligase
1 1 SCOP 56105 SAICAR synthase
1 1 SCOP 56220 DNase I-like
1 1 SCOP 56261 (Glycosyl)asparaginase
1 1 SCOP 56323 ADC synthase
1 1 SCOP 56328 Lactate & malate dehydrogenases, C-terminal domain
1 1 SCOP 56421 Peptide deformylase
1 1 SCOP 56554 Insert subdomain of RNA polymerase alpha subunit
1 1 SCOP 56656 Inositol monophosphatase/fructose-1,6-bisphosphatase-like
1 1 SCOP 56673 DNA polymerase I
1 1 SCOP 56713 Prokaryotic type I DNA topoisomerase
1 1 SCOP 56732 DNA primase DnaG catalytic core
1 1 SCOP 56753 D-aminoacid aminotransferase-like PLP-dependent enzymes
1 1 SCOP 56797 Dehydroquinate synthase, DHQS
1 1 SCOP 56809 Ribosomal protein L1
1 1 SCOP 56895 Aquaporin-like
1 1 SCOP 63588 Glycosyltransferase family 36 C-terminal domain
1 1 SCOP 63701 Prokaryotic PEBP-like proteins
1 1 SCOP 63883 MoeA N-terminal region -like
1 1 SCOP 63912 1,4-beta-N-acetylmuraminidase
1 1 SCOP 63971 Inosicase
1 1 SCOP 64117 tRNA(1-methyladenosine) methyltransferase-like
1 1 SCOP 64198 AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC
1 1 SCOP 64264 Prokaryotic ribosomal protein L17
1 1 SCOP 64369 IPP isomerase-like
1 1 SCOP 64372 3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB
1 1 SCOP 64485 RNA-polymerase beta
1 1 SCOP 64490 RNA-polymerase beta-prime
1 1 SCOP 69602 L-histidinol dehydrogenase HisD
1 1 SCOP 69746 Pseudouridine synthase II TruB
1 1 SCOP 69766 IpsF-like
1 1 SCOP 69865 Argininosuccinate synthetase, C-terminal domain
1 1 SCOP 74656 CoA transferase alpha subunit-like
1 1 SCOP 74657 CoA transferase beta subunit-like
1 1 SCOP 74732 Ribosomal protein L20
1 1 SCOP 74983 Small protein B (SmpB)
1 1 SCOP 75073 Hydantoinase (dihydropyrimidinase), catalytic domain
1 1 SCOP 75079 Renal dipeptidase
1 1 SCOP 75305 Amidase signature (AS) enzymes
1 1 SCOP 75459 Pseudouridine synthase RsuA/RluD
1 1 SCOP 75626 YebC-like
1 1 SCOP 81441 Cytochrome c oxidase subunit I-like
1 1 SCOP 81605 PP2C-like
1 1 SCOP 81642 Cytochrome b of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
1 1 SCOP 81656 Meta-cation ATPase, catalytic domain P
1 1 SCOP 81664 Calcium ATPase, transmembrane domain M
1 1 SCOP 81768 Pre-protein crosslinking domain of SecA
1 1 SCOP 81887 Helical scaffold and wing domains of SecA
1 1 SCOP 82052 Obg GTP-binding protein N-terminal domain
1 1 SCOP 82261 N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain
1 1 SCOP 82267 TatD Mg-dependent DNase-like
1 1 SCOP 82526 Monomeric isocitrate dehydrogenase
1 1 SCOP 82540 Trehalose-6-phosphate synthase, OtsA
1 1 SCOP 82583 G domain-linked domain
1 1 SCOP 82680 N-utilization substance G protein NusG, N-terminal domain
1 1 SCOP 82867 Multidrug efflux transporter AcrB transmembrane domain
1 1 SCOP 88682 Alanine racemase
1 1 SCOP 88683 Eukaryotic ODC-like
1 1 SCOP 89083 Antibiotic binding domain of TipA-like multidrug resistance regulators
1 1 SCOP 89096 GatB/YqeY domain
1 1 SCOP 89508 Glycerophosphoryl diester phosphodiesterase
1 1 SCOP 89624 Ribose/Galactose isomerase RpiB/AlsB
1 1 SCOP 89629 tRNA(m1G37)-methyltransferase TrmD
1 1 SCOP 89724 Macro domain
1 1 SCOP 89797 CoA-transferase family III (CaiB/BaiF)
1 1 SCOP 89800 Deoxycytidylate deaminase-like
1 1 SCOP 90084 Glutaminase
1 1 SCOP 90087 GlpX-like bacterial fructose-1,6-bisphosphatase
1 1 SCOP 90124 ABC transporter transmembrane region
1 1 SCOP 100921 Heat shock protein 70kD (HSP70), peptide-binding domain
1 1 SCOP 100948 Isochorismatase-like hydrolases
1 1 SCOP 101340 HD domain
1 1 SCOP 101354 Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
1 1 SCOP 101875 YceI-like
1 1 SCOP 101905 GyrA/ParC C-terminal domain-like
1 1 SCOP 101984 Pirin-like
1 1 SCOP 102115 Biotin synthase
1 1 SCOP 102317 NagD-like
1 1 SCOP 102406 MoCo carrier protein-like
1 1 SCOP 102646 CoaB-like
1 1 SCOP 102663 Phosphotransacetylase
1 1 SCOP 102706 NIF3 (NGG1p interacting factor 3)-like
1 1 SCOP 102772 YigZ N-terminal domain-like
1 1 SCOP 102928 NifU/IscU domain
1 1 SCOP 103026 Aminomethyltransferase folate-binding domain
1 1 SCOP 103232 Arginine deiminase
1 1 SCOP 103264 Chorismate synthase, AroC
1 1 SCOP 109756 PhoU-like
1 1 SCOP 109771 Nickel-containing superoxide dismutase, NiSOD
1 1 SCOP 110436 Ornithine cyclodeaminase-like
1 1 SCOP 110636 ROK
1 1 SCOP 110739 Glycerate kinase I
1 1 SCOP 111305 Recombination protein RecR
1 1 SCOP 111327 Urocanase
1 1 SCOP 111332 NAD kinase-like
1 1 SCOP 117449 LamB/YcsF-like
1 1 SCOP 117888 Ribosomal protein L16p
1 1 SCOP 118216 Proton glutamate symport protein
1 1 SCOP 140780 TyrA dimerization domain-like
1 1 SCOP 140960 Bacterial tryptophan 2,3-dioxygenase
1 1 SCOP 140991 FtsH protease domain-like
1 1 SCOP 141245 Ribosomal protein L19
1 1 SCOP 141755 PdxS-like
1 1 SCOP 141840 Class-II DAHP synthetase
1 1 SCOP 142177 Histidinol phosphatase-like
1 1 SCOP 142200 YkgG-like
1 1 SCOP 142339 CofD-like
1 1 SCOP 142696 RibA-like
1 1 SCOP 142755 NadA-like
1 1 SCOP 143012 YoeB/Txe-like
1 1 SCOP 143549 Serine dehydratase beta chain-like
1 1 SCOP 143642 LplA-like
1 1 SCOP 143711 LFTR-like
1 1 SCOP 143812 GatB/GatE catalytic domain-like
1 1 SCOP 158600 MgsA/YrvN C-terminal domain-like
1 1 SCOP 159249 PH0987 C-terminal domain-like
1 1 SCOP 159400 Imidazolonepropionase-like
1 1 SCOP 159720 mannose-1-phosphate guanylyl transferase
1 1 SCOP 159756 O-acetyltransferase
1 1 SCOP 159832 PBP transglycosylase domain-like
1 1 SCOP 160370 Ribosomal protein L10-like
1 1 SCOP 160391 MerB-like
1 1 SCOP 160921 PSTPO5379-like
1 1 SCOP 160992 CV3147-like
1 1 SCOP 161071 SNF-like

The following families have one or more weak hits: