Family Assignments

Domains Proteins SCOP Link Families
15 15 SCOP 52686 ABC transporter ATPase domain-like
12 10 SCOP 81269 Extended AAA-ATPase domain
11 11 SCOP 53417 GABA-aminotransferase-like
11 11 SCOP 55682 Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
11 7 SCOP 81268 Tandem AAA-ATPase domain
10 10 SCOP 52375 Class I aminoacyl-tRNA synthetases (RS), catalytic domain
9 9 SCOP 51751 Tyrosine-dependent oxidoreductases
9 9 SCOP 52592 G proteins
5 5 SCOP 52652 Nitrogenase iron protein-like
4 4 SCOP 51487 beta-glycanases
4 4 SCOP 51550 beta-N-acetylhexosaminidase catalytic domain
4 4 SCOP 52318 Class I glutamine amidotransferases (GAT)
4 3 SCOP 52441 BC N-terminal domain-like
4 4 SCOP 52670 RecA protein-like (ATPase-domain)
4 4 SCOP 53272 Phosphoribosyltransferases (PRTases)
4 4 SCOP 53402 Cystathionine synthase-like
4 4 SCOP 53687 Tryptophan synthase beta subunit-like PLP-dependent enzymes
4 2 SCOP 53902 Thiolase-related
4 3 SCOP 56067 BC ATP-binding domain-like
4 2 SCOP 82867 Multidrug efflux transporter AcrB transmembrane domain
4 3 SCOP 89572 Biotin dependent carboxylase carboxyltransferase domain
3 3 SCOP 48558 L-aspartase/fumarase
3 3 SCOP 49803 beta-Galactosidase/glucuronidase, N-terminal domain
3 3 SCOP 51396 FMN-linked oxidoreductases
3 3 SCOP 51446 Amylase, catalytic domain
3 3 SCOP 51553 NagZ-like
3 3 SCOP 51570 Class I aldolase
3 3 SCOP 51883 Aminoacid dehydrogenase-like, C-terminal domain
3 3 SCOP 51990 Glycosyl hydrolases family 6, cellulases
3 3 SCOP 52541 Nucleotide and nucleoside kinases
3 3 SCOP 52778 CAT-like
3 2 SCOP 53068 Actin/HSP70
3 3 SCOP 53384 AAT-like
3 3 SCOP 53653 Arylsulfatase
3 1 SCOP 55974 S-adenosylmethionine synthetase
3 3 SCOP 56802 Acetyl-CoA synthetase-like
3 3 SCOP 142721 PyrH-like
3 3 SCOP 159832 PBP transglycosylase domain-like
2 2 SCOP 47324 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
2 2 SCOP 47918 C-terminal domain of alpha and beta subunits of F1 ATP synthase
2 2 SCOP 48572 HAL/PAL-like
2 2 SCOP 50282 Cold shock DNA-binding domain-like
2 2 SCOP 50448 Elongation factors
2 2 SCOP 50678 ValRS/IleRS/LeuRS editing domain
2 2 SCOP 50892 Cyclophilin (peptidylprolyl isomerase)
2 2 SCOP 51599 Class I DAHP synthetase
2 2 SCOP 52211 Succinyl-CoA synthetase domains
2 2 SCOP 52397 Adenylyltransferase
2 2 SCOP 52901 Glutathione peroxidase-like
2 1 SCOP 53080 Acetokinase-like
2 2 SCOP 53099 Ribonuclease H
2 2 SCOP 53138 Ribosomal protein L18 and S11
2 2 SCOP 53168 Purine and uridine phosphorylases
2 2 SCOP 53329 Formyltransferase
2 2 SCOP 53496 Prolyl oligopeptidase, C-terminal domain
2 2 SCOP 53624 MurCDEF
2 2 SCOP 53721 ALDH-like
2 2 SCOP 53763 UDP-N-acetylglucosamine 2-epimerase
2 2 SCOP 53775 Glutaminase/Asparaginase
2 2 SCOP 53851 Phosphate binding protein-like
2 2 SCOP 53914 Chalcone synthase-like
2 2 SCOP 54212 Translational machinery components
2 1 SCOP 54229 Ribonuclease PH domain 1-like
2 2 SCOP 54632 CBS-domain pair
2 2 SCOP 54815 Prokaryotic type KH domain (KH-domain type II)
2 2 SCOP 55209 Enolpyruvate transferase, EPT
2 1 SCOP 55327 PurM N-terminal domain-like
2 2 SCOP 55348 GAPDH-like
2 2 SCOP 55425 FAD/NAD-linked reductases, dimerisation (C-terminal) domain
2 2 SCOP 55505 Neurolysin-like
2 2 SCOP 55879 DNA gyrase/MutL, N-terminal domain
2 2 SCOP 56350 Lambda integrase-like, catalytic core
2 2 SCOP 56720 Type II DNA topoisomerase
2 2 SCOP 63588 Glycosyltransferase family 36 C-terminal domain
2 2 SCOP 68901 Cytidylytransferase
2 2 SCOP 74911 Aldose 1-epimerase (mutarotase)
2 2 SCOP 75073 Hydantoinase (dihydropyrimidinase), catalytic domain
2 2 SCOP 75621 Release factor
2 2 SCOP 89800 Deoxycytidylate deaminase-like
2 2 SCOP 90124 ABC transporter transmembrane region
2 2 SCOP 101340 HD domain
2 2 SCOP 102118 Oxygen-independent coproporphyrinogen III oxidase HemN
2 2 SCOP 102663 Phosphotransacetylase
2 1 SCOP 110384 Cobalamin-independent methionine synthase
2 1 SCOP 143860 Polyphosphate kinase C-terminal domain
2 2 SCOP 158447 IVS-encoded protein-like
2 2 SCOP 158775 SusD-like
1 1 SCOP 46566 Chaperone J-domain
1 1 SCOP 46610 Fe,Mn superoxide dismutase (SOD), N-terminal domain
1 1 SCOP 46768 Methylated DNA-protein cysteine methyltransferase, C-terminal domain
1 1 SCOP 46947 Ribosomal protein S13
1 1 SCOP 47204 Medium chain acyl-CoA dehydrogenase-like, C-terminal domain
1 1 SCOP 47447 Signal peptide-binding domain
1 1 SCOP 47730 Prokaryotic DNA-bending protein
1 1 SCOP 47786 NAD+-dependent DNA ligase, domain 3
1 1 SCOP 47974 Ribosomal protein S7
1 1 SCOP 48109 Carbamoyl phosphate synthetase, large subunit connection domain
1 1 SCOP 48154 Mismatch glycosylase
1 1 SCOP 48222 N-acylglucosamine (NAG) epimerase
1 1 SCOP 48257 Citrate synthase
1 1 SCOP 48318 Type 2 phosphatidic acid phosphatase, PAP2
1 1 SCOP 48335 DNA repair protein MutS, domain III
1 1 SCOP 48577 Isoprenyl diphosphate synthases
1 1 SCOP 48593 GroEL chaperone, ATPase domain
1 1 SCOP 48711 Di-heme elbow motif
1 1 SCOP 49995 beta-Galactosidase, domain 5
1 1 SCOP 50114 C-terminal domain of ribosomal protein L2
1 1 SCOP 50194 Ribosomal protein L14
1 1 SCOP 50461 Ribosomal protein L3
1 1 SCOP 50466 EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
1 1 SCOP 50476 PNP-oxidase like
1 1 SCOP 50495 Prokaryotic proteases
1 1 SCOP 50693 Pyruvoyl dependent aspartate decarboxylase, ADC
1 1 SCOP 50719 Gln-tRNA synthetase (GlnRS), C-terminal (anticodon-binding) domain
1 1 SCOP 50940 Sialidases (neuraminidases)
1 1 SCOP 50994 Prolyl oligopeptidase, N-terminal domain
1 1 SCOP 51162 UDP N-acetylglucosamine acyltransferase
1 1 SCOP 51165 Tetrahydrodipicolinate-N-succinlytransferase, THDP-succinlytransferase, DapD
1 1 SCOP 51174 gamma-carbonic anhydrase-like
1 1 SCOP 51183 dTDP-sugar isomerase
1 1 SCOP 51191 Type I phosphomannose isomerase
1 1 SCOP 51231 Biotinyl/lipoyl-carrier proteins and domains
1 1 SCOP 51247 BC C-terminal domain-like
1 1 SCOP 51284 dUTPase-like
1 1 SCOP 51352 Triosephosphate isomerase (TIM)
1 1 SCOP 51372 D-ribulose-5-phosphate 3-epimerase
1 1 SCOP 51413 Inosine monophosphate dehydrogenase (IMPDH)
1 1 SCOP 51420 Alanine racemase-like, N-terminal domain
1 1 SCOP 51431 Aldo-keto reductases (NADP)
1 1 SCOP 51591 Class II FBP aldolase
1 1 SCOP 51594 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase)
1 1 SCOP 51605 Enolase
1 1 SCOP 51622 Pyruvate kinase
1 1 SCOP 51714 tRNA-guanine transglycosylase
1 1 SCOP 51718 Dihydropteroate synthetase
1 1 SCOP 51727 Uroporphyrinogen decarboxylase, UROD
1 1 SCOP 51731 Methylenetetrahydrofolate reductase
1 1 SCOP 51800 Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
1 1 SCOP 51848 LDH N-terminal domain-like
1 1 SCOP 51900 CoA-binding domain
1 1 SCOP 51943 FAD/NAD-linked reductases, N-terminal and central domains
1 1 SCOP 52002 R1 subunit of ribonucleotide reductase, C-terminal domain
1 1 SCOP 52017 LeuD-like
1 1 SCOP 52022 Carbamoyl phosphate synthetase, small subunit N-terminal domain
1 1 SCOP 52030 GroEL-like chaperone, apical domain
1 1 SCOP 52081 Ribosomal proteins L15p and L18e
1 1 SCOP 52097 Clp protease, ClpP subunit
1 1 SCOP 52100 Tail specific protease, catalytic domain
1 1 SCOP 52103 Crotonase-like
1 1 SCOP 52122 Lumazine synthase
1 1 SCOP 52142 Uracil-DNA glycosylase
1 1 SCOP 52152 FabD-like
1 1 SCOP 52162 Ribosomal protein L13
1 1 SCOP 52167 Ribosomal protein L4
1 1 SCOP 52256 N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
1 1 SCOP 52305 Type II 3-dehydroquinate dehydratase
1 1 SCOP 52314 Ribosomal protein S2
1 1 SCOP 52331 Aspartyl dipeptidase PepE
1 1 SCOP 52403 N-type ATP pyrophosphatases
1 1 SCOP 52410 PAPS reductase-like
1 1 SCOP 52471 C-terminal domain of the electron transfer flavoprotein alpha subunit
1 1 SCOP 52491 Tubulin, GTPase domain
1 1 SCOP 52513 NagB-like
1 1 SCOP 52584 Phosphoribulokinase/pantothenate kinase
1 1 SCOP 52744 Subtilases
1 1 SCOP 52769 Arginase-like amidino hydrolases
1 1 SCOP 52789 Low-molecular-weight phosphotyrosine protein phosphatases
1 1 SCOP 52926 Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain
1 1 SCOP 52944 ATP synthase (F1-ATPase), gamma subunit
1 1 SCOP 52973 ITPase (Ham1)
1 1 SCOP 52976 Maf-like
1 1 SCOP 53057 beta-carbonic anhydrase, cab
1 1 SCOP 53118 DnaQ-like 3'-5' exonuclease
1 1 SCOP 53179 Peptidyl-tRNA hydrolase-like
1 1 SCOP 53204 Bacterial dinuclear zinc exopeptidases
1 1 SCOP 53224 Aminoacid dehydrogenases
1 1 SCOP 53235 Tetrahydrofolate dehydrogenase/cyclohydrolase
1 1 SCOP 53240 Malic enzyme N-domain
1 1 SCOP 53255 Cofactor-dependent phosphoglycerate mutase
1 1 SCOP 53258 Histidine acid phosphatase
1 1 SCOP 53296 Phosphoribosylpyrophosphate synthetase-like
1 1 SCOP 53354 Protein-L-isoaspartyl O-methyltransferase
1 1 SCOP 53464 glucose-1-phosphate thymidylyltransferase
1 1 SCOP 53598 Dihydrofolate reductases
1 1 SCOP 53629 Folylpolyglutamate synthetase
1 1 SCOP 53650 Alkaline phosphatase
1 1 SCOP 53672 Aspartate/ornithine carbamoyltransferase
1 1 SCOP 53698 double-SIS domain
1 1 SCOP 53701 Phosphoglucose isomerase, PGI
1 1 SCOP 53733 Aconitase iron-sulfur domain
1 1 SCOP 53749 Phosphoglycerate kinase
1 1 SCOP 53760 Peptidoglycan biosynthesis glycosyltransferase MurG
1 1 SCOP 53785 Phosphofructokinase
1 1 SCOP 53791 Tetrapyrrole methylase
1 1 SCOP 53796 PEP carboxykinase C-terminal domain
1 1 SCOP 54224 DNA gyrase/MutL, second domain
1 1 SCOP 54232 GHMP Kinase, N-terminal domain
1 1 SCOP 54535 FKBP immunophilin/proline isomerase
1 1 SCOP 54571 Ribosomal protein S19
1 1 SCOP 54638 4HBT-like
1 1 SCOP 54720 Fe,Mn superoxide dismutase (SOD), C-terminal domain
1 1 SCOP 54737 Ribosomal protein L7/12, C-terminal domain
1 1 SCOP 54748 Ribosomal L11/L12e N-terminal domain
1 1 SCOP 54811 GMP synthetase C-terminal dimerisation domain
1 1 SCOP 54822 Ribosomal protein S3 C-terminal domain
1 1 SCOP 54827 Enolase N-terminal domain-like
1 1 SCOP 54981 EF-G/eEF-2 domains III and V
1 1 SCOP 55000 Ribosomal protein S10
1 1 SCOP 55069 Peptide methionine sulfoxide reductase
1 1 SCOP 55109 D-lactate dehydrogenase
1 1 SCOP 55121 Pseudouridine synthase I TruA
1 1 SCOP 55178 Ribosomal protein S4
1 1 SCOP 55187 Threonyl-tRNA synthetase (ThrRS), second 'additional' domain
1 1 SCOP 55195 Ribosome recycling factor, RRF
1 1 SCOP 55272 DNA repair protein MutS, domain I
1 1 SCOP 55283 Ribosomal protein L5
1 1 SCOP 55299 YjgF/L-PSP
1 1 SCOP 55363 Homoserine dehydrogenase-like
1 1 SCOP 55502 Neutral endopeptidase (neprilysin)
1 1 SCOP 55621 GTP cyclohydrolase I
1 1 SCOP 55730 N-acetyl transferase, NAT
1 1 SCOP 55822 YrdC-like
1 1 SCOP 55832 Thymidylate synthase/dCMP hydroxymethylase
1 1 SCOP 55875 Heat shock protein 90, HSP90, N-terminal domain
1 1 SCOP 55921 Creatinase/aminopeptidase
1 1 SCOP 56038 B3/B4 domain of PheRS, PheT
1 1 SCOP 56043 PurM C-terminal domain-like
1 1 SCOP 56048 Ribosomal protein S8
1 1 SCOP 56054 Ribosomal protein L6
1 1 SCOP 56081 Succinyl-CoA synthetase, beta-chain, N-terminal domain
1 1 SCOP 56096 Adenylation domain of NAD+-dependent DNA ligase
1 1 SCOP 56105 SAICAR synthase
1 1 SCOP 56177 FAD-linked oxidases, N-terminal domain
1 1 SCOP 56184 Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase (MurB), N-terminal domain
1 1 SCOP 56195 Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain
1 1 SCOP 56220 DNase I-like
1 1 SCOP 56236 Class II glutamine amidotransferases
1 1 SCOP 56307 5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain
1 1 SCOP 56328 Lactate & malate dehydrogenases, C-terminal domain
1 1 SCOP 56421 Peptide deformylase
1 1 SCOP 56530 FAH
1 1 SCOP 56543 Substrate-binding domain of HMG-CoA reductase
1 1 SCOP 56646 Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains
1 1 SCOP 56656 Inositol monophosphatase/fructose-1,6-bisphosphatase-like
1 1 SCOP 56673 DNA polymerase I
1 1 SCOP 56713 Prokaryotic type I DNA topoisomerase
1 1 SCOP 56732 DNA primase DnaG catalytic core
1 1 SCOP 56753 D-aminoacid aminotransferase-like PLP-dependent enzymes
1 1 SCOP 56797 Dehydroquinate synthase, DHQS
1 1 SCOP 56809 Ribosomal protein L1
1 1 SCOP 56932 Outer membrane phospholipase A (OMPLA)
1 1 SCOP 56955 Outer membrane efflux proteins (OEP)
1 1 SCOP 63733 Glycosyltransferase family 36 N-terminal domain
1 1 SCOP 63893 Pyridoxine 5'-phosphate synthase
1 1 SCOP 63971 Inosicase
1 1 SCOP 63976 Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC)
1 1 SCOP 63984 Sir2 family of transcriptional regulators
1 1 SCOP 64006 Undecaprenyl diphosphate synthase
1 1 SCOP 64089 BadF/BadG/BcrA/BcrD-like
1 1 SCOP 64168 SurE-like
1 1 SCOP 64198 AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC
1 1 SCOP 64264 Prokaryotic ribosomal protein L17
1 1 SCOP 64372 3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB
1 1 SCOP 64485 RNA-polymerase beta
1 1 SCOP 64490 RNA-polymerase beta-prime
1 1 SCOP 68924 PEP carboxykinase N-terminal domain
1 1 SCOP 69501 DTD-like
1 1 SCOP 69525 Restriction endonuclease HincII
1 1 SCOP 69746 Pseudouridine synthase II TruB
1 1 SCOP 69912 Clc chloride channel
1 1 SCOP 74732 Ribosomal protein L20
1 1 SCOP 74983 Small protein B (SmpB)
1 1 SCOP 75041 SelR domain
1 1 SCOP 75173 beta-Phosphoglucomutase-like
1 1 SCOP 75218 SpoU-like RNA 2'-O ribose methyltransferase
1 1 SCOP 75292 YjeF C-terminal domain-like
1 1 SCOP 75323 Exonuclease RecJ
1 1 SCOP 75459 Pseudouridine synthase RsuA/RluD
1 1 SCOP 75626 YebC-like
1 1 SCOP 81887 Helical scaffold and wing domains of SecA
1 1 SCOP 82052 Obg GTP-binding protein N-terminal domain
1 1 SCOP 82172 DPP6 N-terminal domain-like
1 1 SCOP 82267 TatD Mg-dependent DNase-like
1 1 SCOP 82359 PP-loop ATPase
1 1 SCOP 82371 YbeA-like
1 1 SCOP 82497 DPP6 catalytic domain-like
1 1 SCOP 82526 Monomeric isocitrate dehydrogenase
1 1 SCOP 82583 G domain-linked domain
1 1 SCOP 82661 Poly A polymerase head domain-like
1 1 SCOP 82785 Ohr/OsmC resistance proteins
1 1 SCOP 88683 Eukaryotic ODC-like
1 1 SCOP 88741 Branched-chain alpha-keto acid dehydrogenase Pyr module
1 1 SCOP 88760 TK-like PP module
1 1 SCOP 88766 Branched-chain alpha-keto acid dehydrogenase PP module
1 1 SCOP 88786 C5 cytosine-specific DNA methylase, DCM
1 1 SCOP 88788 N6 adenine-specific DNA methylase, DAM
1 1 SCOP 89503 Ketopantoate hydroxymethyltransferase PanB
1 1 SCOP 89559 NodB-like polysaccharide deacetylase
1 1 SCOP 89624 Ribose/Galactose isomerase RpiB/AlsB
1 1 SCOP 89629 tRNA(m1G37)-methyltransferase TrmD
1 1 SCOP 89724 Macro domain
1 1 SCOP 90084 Glutaminase
1 1 SCOP 100888 Lesion bypass DNA polymerase (Y-family), catalytic domain
1 1 SCOP 100921 Heat shock protein 70kD (HSP70), peptide-binding domain
1 1 SCOP 100948 Isochorismatase-like hydrolases
1 1 SCOP 101354 Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)
1 1 SCOP 101884 Glycosyl hydrolases family 32 N-terminal domain
1 1 SCOP 101905 GyrA/ParC C-terminal domain-like
1 1 SCOP 101961 Stabilizer of iron transporter SufD
1 1 SCOP 102115 Biotin synthase
1 1 SCOP 102406 MoCo carrier protein-like
1 1 SCOP 102575 NOL1/NOP2/sun
1 1 SCOP 102589 LmbE-like
1 1 SCOP 102646 CoaB-like
1 1 SCOP 102656 PdxA-like
1 1 SCOP 102706 NIF3 (NGG1p interacting factor 3)-like
1 1 SCOP 102755 Hsp90 middle domain
1 1 SCOP 102769 ATP-dependent protease Lon (La), catalytic domain
1 1 SCOP 102945 RelA/SpoT domain
1 1 SCOP 103011 Galactokinase
1 1 SCOP 103264 Chorismate synthase, AroC
1 1 SCOP 103482 Multidrug resistance efflux transporter EmrE
1 1 SCOP 103648 TSP type-3 repeat
1 1 SCOP 110284 TM1225-like predicted glycosylases
1 1 SCOP 110396 CutC-like
1 1 SCOP 110636 ROK
1 1 SCOP 110910 Monomeric nicotinate phosphoribosyltransferase C-terminal domain
1 1 SCOP 111305 Recombination protein RecR
1 1 SCOP 111332 NAD kinase-like
1 1 SCOP 111338 QueA-like
1 1 SCOP 117558 Type II thymidine kinase
1 1 SCOP 117888 Ribosomal protein L16p
1 1 SCOP 140479 LemA-like
1 1 SCOP 140932 Fic-like
1 1 SCOP 140991 FtsH protease domain-like
1 1 SCOP 142907 YjbR-like
1 1 SCOP 143265 Dyp-type peroxidase-like
1 1 SCOP 143549 Serine dehydratase beta chain-like
1 1 SCOP 143598 YojJ-like
1 1 SCOP 143642 LplA-like
1 1 SCOP 143711 LFTR-like
1 1 SCOP 143728 PPK middle domain-like
1 1 SCOP 143866 CorA soluble domain-like
1 1 SCOP 143916 RNase Z-like
1 1 SCOP 158588 Jann4075-like
1 1 SCOP 158600 MgsA/YrvN C-terminal domain-like
1 1 SCOP 158833 Tex N-terminal region-like
1 1 SCOP 159112 RNB domain-like
1 1 SCOP 159635 Tex RuvX-like domain-like
1 1 SCOP 159720 mannose-1-phosphate guanylyl transferase
1 1 SCOP 160575 BT0923-like
1 1 SCOP 161094 MgtE membrane domain-like

The following families have one or more weak hits: