SUPERFAMILY is a database of structural and functional annotation for all proteins and genomes.
The SUPERFAMILY annotation is based on a collection of hidden Markov models, which represent structural protein domains at the SCOP superfamily level. A superfamily groups together domains which have an evolutionary relationship. The annotation is produced by scanning protein sequences from over 3,200 completely sequenced genomes against the hidden Markov models.
Paste a protein sequence in FASTA format, or visit the full search page for more options
Browse the SCOP hierarchy
Browse a tree of all the SUPERFAMILY genomes
View a variety of statistics on the structural assignment of 3,200 genomes